Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mikyoung Chang"'
Autor:
Jiayi Yu, Robyn Starr, Hongbo Hu, Shao Cong Sun, George C. Brittain, Xuhong Cheng, Yichuan Xiao, Jin Jin, Mikyoung Chang, Jae Hoon Chang
Publikováno v:
Nature Immunology. 21:1134-1134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3216cbe32df803079d38a2f72c1eb63
https://doi.org/10.1038/s41590-020-0748-8
https://doi.org/10.1038/s41590-020-0748-8
Autor:
Yichuan Xiao, Xuhong Cheng, Jin Jin, Mako Nakaya, Qiang Zou, Shao Cong Sun, Hongbo Hu, Xiaofei Zhou, George C. Brittain, Mikyoung Chang
Publikováno v:
The Journal of Experimental Medicine
TPL2 is required for Th17-mediated neuroinflammation during EAE by regulating the TAK1 signaling axis downstream of the IL-17R in astrocytes.
Development of autoimmune diseases, such as multiple sclerosis and experimental autoimmune encephalomye
Development of autoimmune diseases, such as multiple sclerosis and experimental autoimmune encephalomye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb84cda676abb3c500b010fc9351eb2d
https://doi.org/10.1084/jem.20132640
https://doi.org/10.1084/jem.20132640
Autor:
Xuhong Cheng, Xin Lin, Marzenna Blonska, Xiaofei Zhou, Shao Cong Sun, Mikyoung Chang, Jae Hoon Chang, Mako Nakaya, Yichuan Xiao
Publikováno v:
Immunity. 40:692-705
SummaryGlutamine has been implicated as an immunomodulatory nutrient, but how glutamine uptake is mediated during T cell activation is poorly understood. We have shown that naive T cell activation is coupled with rapid glutamine uptake, which depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40da71a1e84a969ec27bbe1ef567601
https://doi.org/10.1016/j.immuni.2014.04.007
https://doi.org/10.1016/j.immuni.2014.04.007
Autor:
Yong-Hee Lee, Ali Imran, Gwanghee Lee, YounSook Lee, Sang U K Kang, Seok-Hee Park, Mikyoung Chang, Jeong-Hyun Ryou, Jong-Jin Lim, Lee Kwangho
Publikováno v:
Gastroenterology. 156:S82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bc3a40af2cac8255d8bba7079b2388
https://doi.org/10.1053/j.gastro.2019.01.190
https://doi.org/10.1053/j.gastro.2019.01.190
Publikováno v:
Nature Immunology. Oct2009, Vol. 10 Issue 10, p1089-1095. 7p. 1 Black and White Photograph, 1 Diagram, 4 Graphs.
Autor:
Xiaodong Wang, Robert Brink, Christine Stansberg, Xiaofei Zhou, Shao Cong Sun, Jin Jin, Hongbo Hu, Jae Hoon Chang, Øivind Torkildsen, Xuhong Cheng, Yichuan Xiao, George C. Brittain, Mikyoung Chang
Publikováno v:
Nature medicine
Microglia are crucial for the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Here we show that the E3 ubiquitin ligase Peli1 is abundantly expressed in microglia and promotes microglial activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f882a694d27f6d2a60b70486a95bf93d
https://doi.org/10.1038/nm.3111
https://doi.org/10.1038/nm.3111
Autor:
Yichuan Xiao, Anna Zal, Xuhong Cheng, Jae Hoon Chang, Hongbo Hu, Tomasz Zal, Chengming Zhu, Nahum Puebla-Osorio, Shao Cong Sun, Jin Jin, George C. Brittain, Yang Xin Fu, Mikyoung Chang
Publikováno v:
Nature
The non-canonical NF-κB pathway forms a major arm of NF-κB signalling that mediates important biological functions, including lymphoid organogenesis, B-lymphocyte function, and cell growth and survival. Activation of the non-canonical NF-κB pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cd50f3a6af8e7281a20eb8161c7536
https://doi.org/10.1038/nature11831
https://doi.org/10.1038/nature11831
Autor:
Dapeng Zhou, Jiayi Yu, Florence Cammas, Xiaofei Zhou, Shao Cong Sun, Mikyoung Chang, Minying Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 109:20083-20088
T-cell receptor–α (TCRα) rearrangement in CD4 + CD8 + double-positive immature thymocytes is a prerequisite for production of αβ T cells and invariant natural killer T cells. This developmental event is regulated by the TCRα enhancer (Eα), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c749f143bfdba6438893770b71aa0e48
https://doi.org/10.1073/pnas.1214704109
https://doi.org/10.1073/pnas.1214704109
Autor:
Yichuan Xiao, Pingwei Li, Patrick Hwu, Xuhong Cheng, Shao Cong Sun, Wei Jin, Jae Hoon Chang, Jiayi Yu, Brian Rabinovich, Mikyoung Chang, Yi Hong Wang, George C. Brittain, Xiaofei Zhou
Publikováno v:
Nature immunology
T cell activation is subject to tight regulation to avoid inappropriate responses to self antigens. Here we show that genetic deficiency in the ubiquitin ligase Peli1 caused hyperactivation of T cells and rendered T cells refractory to suppression by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b474e9c9ba5b4035dbb63800cd264b7
http://europepmc.org/articles/PMC3178748
http://europepmc.org/articles/PMC3178748
Autor:
Robert H. Bonneau, Xiaofei Zhou, John Hunzeker, Shao Cong Sun, Andrew J. Lee, Mikyoung Chang, Dapeng Zhou
Publikováno v:
The EMBO Journal. 29:1600-1612
Natural killer T (NKT) cells modulate immune responses against pathogens and tumours, as well as immunological tolerance. We show here that CYLD, a tumour suppressor with deubiquitinase function, has a pivotal and cell-intrinsic function in NKT cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae79c7812b24beffc6cf7e4b67486793
https://doi.org/10.1038/emboj.2010.31
https://doi.org/10.1038/emboj.2010.31