Human CYP2D6 varies across the estrous cycle in brains of transgenic mice altering drug response.

Autor: Miksys S; Department of Pharmacology & Toxicology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. Electronic address: s.miksys@utoronto.ca., McDonald C; Department of Pharmacology & Toxicology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada. Electronic address: claire.mcdonald@mail.utoronto.ca., Baghai Wadji F; Department of Pharmacology & Toxicology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada. Electronic address: f.baghaiwadji@utoronto.ca., Gonzalez FJ; Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: gonzalef@mail.nih.gov., Tyndale RF; Department of Pharmacology & Toxicology, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address: r.tyndale@utoronto.ca.

Publikováno v: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2024 Dec 20; Vol. 135, pp. 111108. Date of Electronic Publication: 2024 Jul 26.

Ethanol self‐administration and nicotine treatment increase brain levels of CYP2D in African green monkeys.

Autor: Miller, R. T.¹, Miksys, S.¹, Hoffmann, E.¹, Tyndale, R. F.¹

Publikováno v: British Journal of Pharmacology. Jun2014, Vol. 171 Issue 12, p3077-3088. 12p. 1 Black and White Photograph, 1 Chart, 3 Graphs.

Transgenic mouse, carrier of human CYP2C19 gene, as an animal model for hyperdopaminergism-induced hyperkinesia

Autor: Milosavljević, Filip, Vučić, M., Manojlović, Marina, Ašujić, N., Batinić, Bojan, Novalen, M., Miksys, S., Tyndale, R.F., Ingelman-Sundberg, Magnus, Pešić, Vesna, Jukić, Marin

Publikováno v: European Neuropsychopharmacology

ECNP Workshop for Early Career Scientists in Europe, 7 - 10 March 2019, Nice, France

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4877::c8cefc58ac124fa0eae5063663b4cd07
https://farfar.pharmacy.bg.ac.rs/handle/123456789/3297

Sex, estrous cycle, and hormone regulation of CYP2D in the brain alters oxycodone metabolism and analgesia.

Autor: Arguelles N; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Richards J; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., El-Sherbeni AA; Department of Clinical Pharmacy, Faculty of Pharmacy, Tanta University, Tanta, Egypt., Miksys S; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Canada., Tyndale RF; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address: r.tyndale@utoronto.ca.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2022 Apr; Vol. 198, pp. 114949. Date of Electronic Publication: 2022 Feb 07.

P.358 Reduced cerebellum volume and ataxia-like motoric phenotype in transgenic mouse, carrier of human CYP2C19 gene

Autor: Milosavljević, F., Vučić, M., Manojlović, M., Miloševski, T., Batinić, B., Novalen, M., Miksys, S., Tyndale F, R., Ingelman-Sundberg, M., Pešić, V., Jukić M, M.

Publikováno v: In European Neuropsychopharmacology November 2020 40 Supplement 1:S207-S208