Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miko Schleinitz"'
Publikováno v:
Journal of Molecular Liquids. 283:575-583
Early- and late-stage formulation development for biopharmaceuticals (e.g. therapeutic proteins) remains a challenging task, especially when one has to select suitable excipients to solubilize and stabilize the protein in solution. State-of-the-art f
Publikováno v:
Crystal Growth & Design. 19:3253-3264
Co-crystallization is a promising strategy to enhance the water solubility and bioavailability of active pharmaceutical ingredients (APIs). Once possible coformers have been identified, suitable pr...
Publikováno v:
International journal of pharmaceutics. 569
With respect to all biopharmaceuticals marketed to date, monoclonal antibodies represent the largest fraction with more than 48% market share (2012). However, the development of biopharmaceutical formulations is a challenging task, and time-consuming
Publikováno v:
Crystal Growth & Design. 16:4136-4147
Cocrystal formation processes from aqueous solutions are often affected by pH-dependent dissociation, polymorphic transitions, and formation of hydrates and salts. To enhance the efficiency of those processes, the aqueous stability and solubility of
Publikováno v:
Journal of Molecular Liquids. 298:112011
Within the last decade, thermodynamic models have increasingly grown into the pharmaceutical industry, becoming an essential part in both, process development, as well as formulation development of small-molecule drugs. They are to an increasing degr
Autor:
Miko Schleinitz, Sultan Mohammad, Catarina M. S. S. Neves, Christoph Held, Mara G. Freire, João A. P. Coutinho
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Physical chemistry chemical physics : PCCP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Physical chemistry chemical physics : PCCP
Due to scarce available experimental data, as well as due to the absence of predictive models, the influence of salts on the solubility of ionic liquids (ILs) in water is still poorly understood. To this end, this work addresses the solubility of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0839103a5532f0f9ec09261ecacddc7
http://hdl.handle.net/10773/18149
http://hdl.handle.net/10773/18149