Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Miklos Vegh"'
Autor:
Istvan Gacsalyi, Entire Hegedüs, Miklos Vegh, György Lévay, József Barkóczy, Kompagne Hajnalka, Gábor Kapus, Andras Bilkei-Gorzo, Laszlo G. Harsing, Csilla Leveleki
Publikováno v:
Psychopharmacology. 198:231-241
Although emerging number of data supports the role of glutamate receptors and the potential of their antagonists in anxiety disorders, the involvement of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate receptors in anxiety is
Autor:
Gabor Gigler, Miklos Vegh, Szabolcs Kertesz, József Barkóczy, Annamária Simó, Angéla Benedek, Márta Ágoston, Geza Szabo, Marko Bernadett Martonne, Gábor Szénási, Istvan Gacsalyi, Gábor Kapus, Éva Matucz, Laszlo G. Harsing, György Lévay, Krisztina Moricz, Mihály Albert
Publikováno v:
British Journal of Pharmacology. 152:151-160
Background and purpose: Blockade of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors is a good treatment option for a variety of central nervous system disorders. The present study evaluated the neuroprotective and anticonvulsan
Autor:
Geza Szabo, Miklos Vegh, Gabor Kovacs, Kovacs Attila, Laszlo G. Harsing, Károly Tihanyi, György Lévay
Publikováno v:
Neurochemistry International. 50:555-563
We observed in vitro neuroprotective and AMPA/kainate receptor antagonist effects of the new 2,3-benzodiazepine derivative EGIS-8332 (R,S-1-(4-aminophenyl)-7,8-methylenedioxy-4-cyano-4-methyl-3-N-acetyl-5H-3,4-dihydro-2,3-benzodiazepine) using the la
Autor:
József Barkóczy, Michael Spedding, Mihály Albert, Gyula Simig, Szabolcs Kertesz, Gábor Kapus, Zoltan Greff, Geza Szabo, Laszlo G. Harsing, Gábor Szénási, Miklos Vegh, István Ling
Publikováno v:
Neurochemistry international. 52(1-2)
AMPA receptors are fast ligand-gated members of glutamate receptors in neuronal and many types of non-neuronal cells. The heterotetramer complexes are assembled from four subunits (GluR1-4) in region-, development- and function-selective patterns. Ea
Autor:
József Barkóczy, Szabolcs Kertesz, Annamária Simó, György Lévay, Gábor Kapus, Laszlo G. Harsing, Miklos Vegh, Gabor Gigler, Geza Szabo
Publikováno v:
Pharmaceutical research. 21(2)
AMPA receptor-mediated excitotoxicity is thought to be a critical process in diseases accompanied by neuronal cell loss following a hypoxic/anoxic state of the central nervous system. It has been suggested that blockade of AMPA receptors might result
Publikováno v:
European Neuropsychopharmacology. 18:S346-S347
Autor:
Szabolcs Kertesz, L.G. Harsing, Gabor Gigler, Gábor Kapus, György Lévay, Miklos Vegh, G. Simig, Gábor Szénási, J. Wellmann, József Barkóczy
Publikováno v:
European Neuropsychopharmacology. 17:S267-S268
Publikováno v:
Biochimica et biophysica acta. 1023(2)
Vanadate-sensitized photocleavage of the Ca2(+)-ATPase of rabbit sarcoplasmic reticulum was observed upon illumination of sarcoplasmic reticulum vesicles or the purified Ca2(+)-ATPase by ultraviolet light in the presence of 1 mM monovanadate or decav
P.3.021 Selective AMPA receptor antagonist GYKI 52466 is effective in three animal models of anxiety
Publikováno v:
European Neuropsychopharmacology. 13:S362
Publikováno v:
Journal of Biological Chemistry. 264:17816-17823
The mycotoxin, cyclopiazonic acid (CPA), inhibits the Ca2+-stimulated ATPase (EC 3.6.1.38) and Ca2+ transport activity of sarcoplasmic reticulum (Goeger, D. E., Riley, R. T., Dorner, J. W., and Cole, R. J. (1988) Biochem. Pharmacol. 37, 978-981). We