Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Miklos Salgo"'
Autor:
Miguel Górgolas, Schlomo Staszewski, Lucy Rowell, Piotr Pulik, Joaquin Portilla, Adrian Streinu-Cercel, Wulf Böcher, Sorin Rugină, Matthias Stoll, Miklos Salgo, Markus Müller
Publikováno v:
HIV Clinical Trials. 9:375-386
Treatment-related toxicities frequently limit antiretroviral therapy for patients with HIV-1 infection. This study evaluated the changes in treatment-limiting toxicities when the primary toxicity-causing agent was replaced with enfuvirtide.Adult pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab24cf38840ce86cbcbf514448fb2e7
https://doi.org/10.1310/hct0906-375
https://doi.org/10.1310/hct0906-375
Autor:
David Wright, Ralph DeMasi, Anna Shikhman, Jain Chung, Neil M.H. Graham, Emily Labriola-Tompkins, Yu Yuan Chiu, Allen E. Rodriguez, Ernestine Tucker, Sharon Walmsley, Lucille Donatacci, Lucy Rowell, Miklos Salgo, Eliot Godofsky
Publikováno v:
HIV Clinical Trials. 9:73-82
To evaluate the safety and antiviral activity of once-daily (qd) enfuvirtide (ENF) compared with twice daily (bid) ENF.T20-401 was a phase 2, open-label, randomized, 48-week pilot study comparing ENF 180 mg qd versus ENF 90 mg bid, added to an optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4e8b8adf25dafbab88af32ebb20e45
https://doi.org/10.1310/hct0902-73
https://doi.org/10.1310/hct0902-73
Autor:
Ralph DeMasi, Emily Labriola-Tompkins, Anna Shikhman, Lucy Rowell, James Thommes, Miklos Salgo, Denise Guimaraes, Edwin DeJesus, Cynthia Wat, Jürgen K. Rockstroh, Lucille Donatacci, Anne Bertasso, Belinda Atkins, Martin Wilkinson
Publikováno v:
AIDS Research and Human Retroviruses. 24:141-148
High adherence rates to antiretroviral (ARV) therapy are associated with increased durability of viral suppression and decreased rates of drug resistance. The requirement of twice-daily subcutaneous self-administration of enfuvirtide (ENF) has raised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047d127669862b412df64524adbb1927
https://doi.org/10.1089/aid.2006.0231
https://doi.org/10.1089/aid.2006.0231
Autor:
Tom Melby, Prakash R. Sista, N. Roberts, Gabrielle Heilek-Snyder, T J Matthews, T. Kirkland, Michael L. Greenberg, Ralph DeMasi, Miklos Salgo, Nick Cammack
Publikováno v:
AIDS Research and Human Retroviruses. 22:375-385
Enfuvirtide (T-20) is the first entry inhibitor approved for treatment of HIV infection and acts by inhibiting conformational changes in the viral envelope protein gp41 that are necessary for fusion of the virus and host cell membranes. Here we prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d8b8cd716ccf5629c14fa3104db5cd
https://doi.org/10.1089/aid.2006.22.375
https://doi.org/10.1089/aid.2006.22.375
Autor:
Christine Katlama, Jain Chung, François Raffi, Miklos Salgo, Lynn M. Smiley, Martin Wilkinson, Michael S. Saag
Publikováno v:
Clinical Infectious Diseases. 42:870-877
Background. Early virological response to antiretroviral therapy is predictive of long-term treatment outcome in therapy-naive patients. In treatment-experienced patients, such correlations are less well defined, because initial responses may be less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b01cce6b7f8f2805679259ee2f5f38c
https://doi.org/10.1086/500206
https://doi.org/10.1086/500206
Autor:
Zarina Gafoor, Jain Chung, Denise Guimaraes, Julio S. G. Montaner, Miklos Salgo, Ralph DeMasi
Publikováno v:
HIV Clinical Trials. 6:281-290
Determinants of therapeutic success are poorly characterized in patients with extensive HAART experience. Positive prognostic factors (PPFs) in the TORO trials could serve as the basis for a prognostically meaningful staging of treatment-experienced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c2d53764761d836380f479cbfa6524
https://doi.org/10.1310/0xh7-f2v2-1k0r-nu2w
https://doi.org/10.1310/0xh7-f2v2-1k0r-nu2w
Autor:
S. Janumpalli, T J Matthews, Tom Melby, S. M. Mosier, J. Erickson, D. Lambert, D. Davison, Miklos Salgo, S. A. Stanfield-Oakley, Nick Cammack, M. Mink, Prakash Sista, Lei Jin, Michael L. Greenberg
Publikováno v:
Journal of Virology. 79:12447-12454
Enfuvirtide (ENF), a novel human immunodeficiency virus type 1 (HIV-1) fusion inhibitor, has potent antiviral activity against HIV-1 both in vitro and in vivo. Resistance to ENF observed after in vitro passaging was associated with changes in a three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0db43009c0068ae530ceb44a5c726d9
https://doi.org/10.1128/jvi.79.19.12447-12454.2005
https://doi.org/10.1128/jvi.79.19.12447-12454.2005
Autor:
Mike Mink, Thomas J. Matthews, Donna K. Davison, Sarah M. Mosier, Ralph DeMasi, Lei Jin, Prakash Sista, Emily L. Nelson, Nick Cammack, Miklos Salgo, Michael L. Greenberg, Tom Melby
Publikováno v:
AIDS. 18:1787-1794
Enfuvirtide (ENF) is the first of a novel class of drugs that block HIV gp41-mediated viral fusion to host cells. Viruses with mutations at positions 36-38 in HIV-1 gp41 and/or reduced susceptibility to ENF have been selected both in vitro and in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69aef78817afc9a2aa21433d34fa6b2
https://doi.org/10.1097/00002030-200409030-00007
https://doi.org/10.1097/00002030-200409030-00007
Publikováno v:
Reviews in Medical Virology. 14:321-337
The end of the twentieth century saw dramatic improvements in the prognosis of HIV infection brought about by the introduction of new agents (the protease inhibitors and the non-nucleoside reverse transcriptase inhibitors) and their use in highly act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b46afe37fb42184f155b6bd28d3a86
https://doi.org/10.1002/rmv.440
https://doi.org/10.1002/rmv.440
Autor:
Donna Cunningham, Jiang Qian, Douglas G. Fish, Miklos Salgo, Peter J. Piliero, George L. Drusano, Tosca Kinchelow, Sandra L. Preston
Publikováno v:
Clinical Infectious Diseases. 36:e111-e114
We report a case of acute Guillain-Barré syndrome (GBS) associated with a prompt and vigorous immune reconstitution and decrease in the virus load noted during treatment with a potent regimen of highly active antiretroviral therapy. We hypothesize t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fed4513b9ce4b45a832a48723d68b4
https://doi.org/10.1086/368311
https://doi.org/10.1086/368311