Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Miklos Gellai"'
Autor:
Ming-Yu Lo, Jeffrey M. Voigt, Lisa C. Contino, M. J. Morcillo, Jorge Manzanares, Shih Ann Chen, Mitsuo Kosaka, Penelope A. Longhurst, Chuen-Wang Chiou, David P. Brooks, Chia-Cheng Yu, Takahiko Aoki, Belinda Benhamu, Hiroshi Sobajima, Kuniharu Mizuno, Miklos Gellai, Anne G. Caicoya, Mercedes Delgado, Francisco J. Rubia, Miguel A. Pozo, Jong-Khing Huang, Akihiro Taimura, Jill R. Hayes, Howard D. Colby, Takaaki Matsumoto, María L. López-Rodríguez, Timothy Othman, Deanne M. Nowak, Paul K.S. Chan, Kyung Hwan Kim, Jung-Yaw Lin, Richard M. Edwards, María E. Beneytez, Mitsuhiro Makino, Jeong-Beom Lee, Shinji Goto, Tsunemasa Suzuki, José A. Fuentes, Takeshi Suzuki, Hye-Young Kim, Yi-Jen Chen, Tso-Hsiao Chen, Kaori Taniko, Feng-Lin Hsu, Chung-Ren Jan, Hiromi Sassa, Jun-Jen Chang, Chin-Feng Tsai, Xiaoshi Zhang
Publikováno v:
Pharmacology. 62:249-252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093221ac494534ddb4dac032211f8414
https://doi.org/10.1159/000056104
https://doi.org/10.1159/000056104
Autor:
David P. Brooks, Ponnal Nambi, Chandrika Kumar, Mark Pullen, Jamie Kincaid, Nambi Aiyar, Miklos Gellai, Parvathi Nuthulaganti
Publikováno v:
Molecular Pharmacology. 52:582-589
This study demonstrates the presence of a novel endothelin (ET) receptor subtype that displays high affinity for both ETA- and ETB-selective ligands. This subtype has been identified in canine spleen membranes using ETB-selective agonists ET-3, IRL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c7cb34c4548528d4c0ef713d1350d4
https://doi.org/10.1124/mol.52.4.582
https://doi.org/10.1124/mol.52.4.582
Autor:
TianM Chen, Robert M. Levin, David Russel, Harry J. Wilbur, Robin De Wolf, Tracey Fletcher, Paul Calabresi, Ming Y.W. Chu, Shailendra Kumar, Miklos Gellai, John Zalcberg, Laura J. Mogavero, Mel H. Epstein, Milton H. Lipsky, Hemendra N. Bhargava, Gail G. Snitkoff, Wei-zheng. Zhang, Paul W. Finch, Walter Cosolo, Tamar J. Nicholas, Lorrin K Yee, Thomas Maciag, Ponnal Nambi, Stanley Friedman, Hyung-Min Kim, James Mandell
Publikováno v:
Pharmacology. 55:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44824031cc67255cd699ad716522c6b
https://doi.org/10.1159/000139537
https://doi.org/10.1159/000139537
Autor:
Miklos Gellai
Publikováno v:
Current Opinion in Nephrology and Hypertension. 6:64-68
Even though the pharmacology of the endothelin receptor subtypes ETB and ETB is well characterized, their physiological role in the control of basal vascular tone is poorly understood. It has been proposed that a tonic vasoconstriction mediated by en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b59239cbf900794f58289a8f26883a0
https://doi.org/10.1097/00041552-199701000-00012
https://doi.org/10.1097/00041552-199701000-00012
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R254-R261
The physiological roles of endothelin-B (ETB) receptor subtypes in systemic and renal hemodynamics were assessed in conscious Sprague-Dawley rats. Mean arterial pressure, hindlimb flow, and renal blood flow were measured via an implanted catheter and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d02212a1a4cb4a03a71a48d84cbbf4
https://doi.org/10.1152/ajpregu.1996.271.1.r254
https://doi.org/10.1152/ajpregu.1996.271.1.r254
Autor:
Mildred Ezekiel, John D. Elliott, Stephen A. Douglas, Eliot H. Ohlstein, Miklos Gellai, Giora Z. Feuerstein
Publikováno v:
Hypertension. 25:818-822
Abstract Indirect evidence has implicated endothelin-1 in the pathogenesis of hypertension. In the present study we examined such a role directly with SB 209670, a novel nonpeptide endothelin receptor antagonist. The antihypertensive and hemodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccd2dc8bf5f98302f0eb1210c3f1510
https://doi.org/10.1161/01.hyp.25.4.818
https://doi.org/10.1161/01.hyp.25.4.818
Publikováno v:
Journal of Clinical Investigation. 93:900-906
Studies were designed to examine the effect of a selective endothelinA (ETA) receptor antagonist, BQ123, on severe postischemic acute renal failure (ARF) in Sprague-Dawley rats. Severe ARF was induced in uninephectomized, chronically instrumented rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfe9962da742116a72fc9124fb68e4b
https://doi.org/10.1172/jci117046
https://doi.org/10.1172/jci117046
Autor:
Robert G. Franz, Dimitri Gaitanopoulos, Eliot H. Ohlstein, Richard M. Edwards, Miklos Gellai, David T. Hill, David P. Brooks, Todd A. Frederickson, Nambi Aiyar, Drake S. Eggleston, Joseph Weinstock, Edwin F. Weidley, Richard M. Keenan, Gerald R. Girard, Elayne Griffin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:23-28
SB 203220 (9), the naphthyl analog of SK&F 108566(1), is a potent long-acting AT-1 antagonist. In comparison to 1, which is a competitive antagonist, 9 is a partially unsurmountable antagonist with a slower receptor off-rate, a greater resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61668b23b7eb3f8fd8bf4470e1ca21b8
https://doi.org/10.1016/s0960-894x(01)81116-1
https://doi.org/10.1016/s0960-894x(01)81116-1
Autor:
T. A. Frederickson, Dimitri Gaitanopoulos, David T. Hill, Nambi Aiyar, E. Griffin, R. G. Franz, E. H. Ohlstein, Miklos Gellai, G. R. Girard, D. S. Eggleston, E. F. Weidley, Joseph Weinstock, David P. Brooks, R. M. Edwards, Richard M. Keenan
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::343c488ca380b4e0c20b6a9aada7a2c5
https://doi.org/10.1002/chin.199426146
https://doi.org/10.1002/chin.199426146