Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Miklos Gaszner"'
Autor:
Jacqueline Dickson, Humaira Gowher, Ruslan Strogantsev, Miklos Gaszner, Alan Hair, Gary Felsenfeld, Adam G West
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000804 (2010)
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states. Chromatin insulator or barrier elements are key components of these processes
Externí odkaz:
https://doaj.org/article/39dbccdbc4e343b4923ed8cdbf91d599
Autor:
Peter Jackman, Miklos Gaszner
Publikováno v:
Industrial Biotechnology. 14:123-125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d7c365eccce2a8b162a086640640325
https://doi.org/10.1089/ind.2018.29130.pja
https://doi.org/10.1089/ind.2018.29130.pja
Publikováno v:
Molecular Cell. 16(3):453-463
The chicken beta-globin 5'HS4 insulator element acts as a barrier to the encroachment of chromosomal silencing. Endogenous 5'HS4 sequences are highly enriched with histone acetylation and H3K4 methylation regardless of neighboring gene expression. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f0555a7e4d026e17f5e6774d94a515
Publikováno v:
Genes & Development. 17:664-675
Although it is now well-established that boundary elements/insulators function to subdivide eukaryotic chromosomes into autonomous regulatory domains, the underlying mechanisms remain elusive. One idea is that boundaries act as barriers, preventing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3f4135156e6ce8dbcc66c359aaf586
https://doi.org/10.1101/gad.1052003
https://doi.org/10.1101/gad.1052003
Autor:
Adam C. Bell, Félix Recillas-Targa, Bonnie Burgess-Beusse, Michael D. Litt, Adam G. West, Michael J. Pikaart, Gary Felsenfeld, Miklos Gaszner
Publikováno v:
Proceedings of the National Academy of Sciences. 99:6883-6888
The 1.2-kb DNA sequence element (5′HS4) at the 5′ end of the chicken β-globin locus has the two defining properties of an insulator: it prevents an “external” enhancer from acting on a promoter when placed between them (“enhancer blocking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491f52f6c45c60f2c3322b3dc8d2fa3a
https://doi.org/10.1073/pnas.102179399
https://doi.org/10.1073/pnas.102179399
Publikováno v:
Genes & Development. 16:271-288
Eukaryotic genomes are organized into domains containing individual genes and gene clusters that have distinct patterns of expression both during development and in differentiated cells. These genomes contain regulatory elements such as enhancers tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029b9503a36b99144a64410ec767f09e
https://doi.org/10.1101/gad.954702
https://doi.org/10.1101/gad.954702
Autor:
I. Hogga, Miklos Gaszner, M. Galloni, J. Gausz, Andor Udvardy, Henrik Gyurkovics, Martin Muller, Julio Vazquez, Kirsten Hagstrom, László Sipos, F. Karch, G. Farkas, Paul Schedl
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 58:45-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67776f6240f26c37201af447009c6bb0
https://doi.org/10.1101/sqb.1993.058.01.008
https://doi.org/10.1101/sqb.1993.058.01.008
Autor:
Miklos Gaszner, Ruslan Strogantsev, Humaira Gowher, Gary Felsenfeld, Alan Hair, Adam G. West, Jacqueline Dickson
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000804 (2010)
Dickson, J, Gowher, H, Strogantsev, R, Gaszner, M, Hair, A, Felsenfeld, G & West, A G 2010, ' VEZF1 elements mediate protection from DNA methylation ', PLoS Genetics, vol. 6, no. 1, pp. e1000804 . https://doi.org/10.1371/journal.pgen.1000804
PLoS Genetics
Dickson, J, Gowher, H, Strogantsev, R, Gaszner, M, Hair, A, Felsenfeld, G & West, A G 2010, ' VEZF1 elements mediate protection from DNA methylation ', PLoS Genetics, vol. 6, no. 1, pp. e1000804 . https://doi.org/10.1371/journal.pgen.1000804
PLoS Genetics
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states. Chromatin insulator or barrier elements are key components of these processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5fcf5f131ba616ccd3fb66ecc30381
https://eprints.gla.ac.uk/36517/1/36517.pdf
https://eprints.gla.ac.uk/36517/1/36517.pdf
Autor:
Gary Felsenfeld, Miklos Gaszner
Publikováno v:
Nature reviews. Genetics. 7(9)
Insulators are DNA sequence elements that prevent inappropriate interactions between adjacent chromatin domains. One type of insulator establishes domains that separate enhancers and promoters to block their interaction, whereas a second type creates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af834d573d4a07848190a7630b1d9cc
https://pubmed.ncbi.nlm.nih.gov/16909129
https://pubmed.ncbi.nlm.nih.gov/16909129
Autor:
Timur M. Yusufzai, R. Ghirlando, Frédérique Magdinier, Miklos Gaszner, Vesco Mutskov, Hideaki Tagami, Michael D. Litt, Catherine M. Farrell, Bonnie Burgess-Beusse, C. Jin, Gary Felsenfeld, Adam G. West, Yoshihiro Nakatani, S. Huang
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology
Cold Spring Harbor Symposia on Quantitative Biology, Cold Spring Harbor Laboratory; 1999, 2004, 69, pp.245-250. ⟨10.1101/sqb.2004.69.245⟩
Cold Spring Harbor Symposia on Quantitative Biology, Cold Spring Harbor Laboratory; 1999, 2004, 69, pp.245-250. ⟨10.1101/sqb.2004.69.245⟩
International audience; Insulator elements were first described in Drosophila, but subsequent studies have shown that they are present in vertebrates as well (for review, see West et al. 2002). Over the past several years we have focused our attentio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee10a97e20fafa849fe871ce3322ba8
https://pubmed.ncbi.nlm.nih.gov/16117655
https://pubmed.ncbi.nlm.nih.gov/16117655