Výsledky vyhledávání - "Miklos D Kertai"

Akademický článek

Limited clinical utility for GWAS or polygenic risk score for postoperative acute kidney injury in non-cardiac surgery in European-ancestry patients

Autor: Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Anik Sinha, Nicholas J. Douville, Michael Heung, Michael R. Mathis, Jonathan D. Mosley, Jonathan P. Wanderer, Sachin Kheterpal, Matthew Zawistowski, Chad M. Brummett, Edward D. Siew, Cassianne Robinson-Cohen, Miklos D. Kertai

Publikováno v: BMC Nephrology, Vol 23, Iss 1, Pp 1-11 (2022)

Abstract Background Prior studies support a genetic basis for postoperative acute kidney injury (AKI). We conducted a genome-wide association study (GWAS), assessed the clinical utility of a polygenic risk score (PRS), and estimated the heritable com

Externí odkaz: https://doaj.org/article/813edc1012fa4c88a501d1fbf8d0c6be

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Akademický článek

PeRiOperative Glucose PRAgMatic (PROGRAM) trial protocol and statistical analysis plan for comparing automated intraoperative reminders to standardise insulin administration in surgical patients at high risk of hyperglycaemia

Autor: Karen McCarthy, Robert E Freundlich, Matthew D McEvoy, Matthew S Shotwell, Svetlana Eden, Miklos D Kertai, Jonathan P Wanderer, Matthew Zapf, Dev Patel, Patrick Henson, Eunice Huang, Leslie Fowler

Publikováno v: BMJ Open, Vol 13, Iss 8 (2023)

Introduction Studies finding perioperative hyperglycaemia is associated with adverse patient outcomes in surgical procedures spurred the development of blood glucose guidelines at many institutions. In this trial, we will assess the implementation of

Externí odkaz: https://doaj.org/article/dd57f3a0d6e244fabb1f8e2d75195de9

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Akademický článek

Genetic predisposition may not improve prediction of cardiac surgery-associated acute kidney injury

Autor: Nicholas J. Douville, Daniel B. Larach, Adam Lewis, Lisa Bastarache, Anita Pandit, Jing He, Michael Heung, Michael Mathis, Jonathan P. Wanderer, Sachin Kheterpal, Ida Surakka, Miklos D. Kertai

Publikováno v: Frontiers in Genetics, Vol 14 (2023)

Background: The recent integration of genomic data with electronic health records has enabled large scale genomic studies on a variety of perioperative complications, yet genome-wide association studies on acute kidney injury have been limited in siz

Externí odkaz: https://doaj.org/article/6e9fe0d4416b4fc6be7ccf6f263fab07

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Akademický článek

Developing a risk stratification tool for predicting opioid-related respiratory depression after non-cardiac surgery: a retrospective study

Autor: Matthew S Shotwell, Miklos D Kertai, Stephen Bruehl, Thomas van de Ven, Sounak Roy, Xiaoke Feng, Andrew D Shaw

Publikováno v: BMJ Open, Vol 12, Iss 9 (2022)

Objectives Accurately assessing the probability of significant respiratory depression following opioid administration can potentially enhance perioperative risk assessment and pain management. We developed and validated a risk prediction tool to esti

Externí odkaz: https://doaj.org/article/51a854cf6cf049c5ae2aa7ac4536a58c

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Processed Electroencephalographic Use During Anesthesia and Outcomes: Analysis of The Society of Thoracic Surgeons Adult Cardiac Surgery Database

Autor: Ashish S. Shah, Sounak Roy, Xiaoke Feng, Matthew S. Shotwell, Miklos D. Kertai, Frederick W. Lombard

Publikováno v: The Annals of Thoracic Surgery. 114:1688-1694

Background This study assessed associations between processed electroencephalographic (pEEG) use during anesthesia, surgery- and anesthesia-related risk factors, and neurologic outcomes and mortality after cardiac surgery. Methods Drawing from the So

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc881f8c027addaf95fc355523ec4a0
https://doi.org/10.1016/j.athoracsur.2021.09.049

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