Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Miklós Simonyi"'
Autor:
Krisztina Németh, Réka Mizsei, Laszlo Jicsinszky, Júlia Visy, Miklós Simonyi, Gábor Tárkányi, Julianna Szemán, Lajos Szente, Orsolya Tőke
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 72:292-298
Inclusion complexes of warfarin enantiomers with permethylated monoamino-β-cyclodextrin (PMMABCD) were characterized using CE and (1)H NMR spectroscopy in aqueous solution. These techniques gave complementary information on the stability and the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a55b5ff04ddcdae2df2b1f4be858bf9
https://doi.org/10.1016/j.jpba.2012.09.003
https://doi.org/10.1016/j.jpba.2012.09.003
Autor:
Miklós Simonyi, Róbert Iványi, Laszlo Jicsinszky, Júlia Visy, Krisztina Németh, Antal Péter, Enikő Forró, Lajos Szente, Erzsébet Varga, Ferenc Fülöp, Julianna Szemán
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 53:382-388
Chiral separation of 19 pairs of cis-beta-lactam (BL) stereoisomers of pharmacological importance was examined by capillary electrophoresis using cyclodextrin (CD) derivatives. In order to select the most effective conditions separating the highest n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a196cad436a2dd140eed1ec3ccb3d8d8
https://doi.org/10.1016/j.jpba.2010.04.026
https://doi.org/10.1016/j.jpba.2010.04.026
Selective binding interactions of deramciclane to the genetic variants of human α1-acid glycoprotein
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1800:367-372
Background α1-Acid glycoprotein (AGP) plays a decisive role in the serum protein binding of several drugs.Genetic variants of AGP have different ligand binding properties. The binding of deramciclane (DER), a chiral anxiolytic agent, has been studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6334576064dc620e6ebb550d76e77dab
https://doi.org/10.1016/j.bbagen.2009.08.006
https://doi.org/10.1016/j.bbagen.2009.08.006
Autor:
Júlia Visy, Krisztina Németh, Gábor Tárkányi, Miklós Simonyi, Laszlo Jicsinszky, Orsolya Toke, Róbert Iványi, Julianna Szemán, Gábor Varga, Lajos Szente
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 51:84-89
Preparation of (6-monoureido-6-monodeoxy) permethylated beta-cyclodextrin bonded chiral stationary phase from permethylated 6-monoamino-6-monodeoxy-beta-cyclodextrin is described. The optimized chiral stationary phase was evaluated by using HPLC sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f5d3028ef1cebd93021edcd7395198
https://doi.org/10.1016/j.jpba.2009.08.009
https://doi.org/10.1016/j.jpba.2009.08.009
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:4857-4862
Diazepam, a 1,4-benzodiazepine lacking chiral centre, exists in an equimolar mixture of two chiral conformers. Induced circular dichroism spectra for the binding of diazepam and its 3,3-dimethyl substituted analogues to alpha1-acid glycoprotein (AGP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23db7f073b647c2f769475c07d6718ec
https://doi.org/10.1016/j.bmc.2007.04.060
https://doi.org/10.1016/j.bmc.2007.04.060
Publikováno v:
Journal of Polymer Science: Polymer Symposia. 40:163-167
4,4′-isopropylidene-bisphenol and some of its methyl and tert-butyl derivatives were studied by inhibiting the radical polymerization of vinyl acetate. Alkyl groups in the bisphenol increase the radical reactivity. The substituent effect is signifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70b0f7bb9d9535d44d566eff7725408
https://doi.org/10.1002/polc.5070400120
https://doi.org/10.1002/polc.5070400120
Autor:
Hans Dieter Martin, Miklós Simonyi, Bente Jeanette Foss, Zsolt Bikádi, Ferenc Zsila, Vassilia Partali, Bernhard Mayer, Hans-Richard Sliwka, Christian Köpsel
Publikováno v:
Chemistry - A European Journal. 11:4103-4108
Enantiomers of glycerophospholipids show low or no optical activity. Accordingly, optical activity was not observed with the R enantiomer of a highly unsaturated carotenoyl lysophospholipid in solution. In spite of this, strong Cotton effects are det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44168d070c139097604017592c4dd097
https://doi.org/10.1002/chem.200401191
https://doi.org/10.1002/chem.200401191
Publikováno v:
Journal of Computer-Aided Molecular Design. 19:271-285
Previously, our laboratory demonstrated that one cytochrome P450 isoenzyme can influence the catalytic properties of another P450 isoenzyme when combined in a reconstituted system. Moreover, our data and that of other investigators indicate that P450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ab06f394db66971aef9f0f06a727ce
https://doi.org/10.1007/s10822-005-4995-4
https://doi.org/10.1007/s10822-005-4995-4
Publikováno v:
Helvetica Chimica Acta. 87:2159-2168
Circular dichroism (CD) spectroscopy was used to distinguish between the isomeric (all-E)-configured 3′-epilutein (2) and 6′-epilutein (8) to establish the absolute configuration of epilutein samples of different (natural and semisynthetic) origi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02b0ecca18974b75fd02763cac992699
https://doi.org/10.1002/hlca.200490195
https://doi.org/10.1002/hlca.200490195
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:3239-3245
This paper reports the first experimental evidence on binding of the plant derived curcumin molecule to human alpha1-acid glycoprotein (AGP), an acute phase protein in blood. Oppositely signed induced circular dichroism (CD) bands measured in the vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03707dea66a86bc83dfaf68f3d4af1ca
https://doi.org/10.1016/j.bmc.2004.03.074
https://doi.org/10.1016/j.bmc.2004.03.074