Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Miklós S Z, Kellermayer"'
Autor:
Cristina M. Șulea, Zsolt Mártonfalvi, Csilla Csányi, Dóra Haluszka, Miklós Pólos, Bence Ágg, Roland Stengl, Kálmán Benke, Zoltán Szabolcs, Miklós S. Z. Kellermayer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7561 (2023)
Fibrillin-1 microfibrils are essential elements of the extracellular matrix serving as a scaffold for the deposition of elastin and endowing connective tissues with tensile strength and elasticity. Mutations in the fibrillin-1 gene (FBN1) are linked
Externí odkaz:
https://doaj.org/article/364134d147114547a5b1ed97abdffb79
Autor:
Dominik Sziklai, Judit Sallai, Zsombor Papp, Dalma Kellermayer, Zsolt Mártonfalvi, Ricardo H. Pires, Miklós S. Z. Kellermayer
Publikováno v:
Nanomaterials, Vol 12, Iss 2, p 178 (2022)
Titin is a multifunctional filamentous protein anchored in the M-band, a hexagonally organized supramolecular lattice in the middle of the muscle sarcomere. Functionally, the M-band is a framework that cross-links myosin thick filaments, organizes as
Externí odkaz:
https://doaj.org/article/72e54c4d75634babb920d5298385c583
Autor:
Irene Pertici, Lorenzo Bongini, Luca Melli, Giulio Bianchi, Luca Salvi, Giulia Falorsi, Caterina Squarci, Tamás Bozó, Dan Cojoc, Miklós S. Z. Kellermayer, Vincenzo Lombardi, Pasquale Bianco
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
There is interest in mimicking striated muscle for a range of applications including nanomachines. Here, the authors report on synthetic 1D nanomachines which are used to study an ensemble of myosin motors interacting with an actin filament with pote
Externí odkaz:
https://doaj.org/article/16fbfc6e8fe5445194ce1e7708187851
Autor:
Mária Csilla Csányi, Pál Salamon, Tímea Feller, Tamás Bozó, Jolán Hársfalvi, Miklós S. Z. Kellermayer
Publikováno v:
Protein Science. 32
The von Willebrand factor (VWF) is a multimeric glycoprotein composed of 80- to 120-nm-long protomeric units and plays a fundamental role in mediating platelet function at high shear. The exact nature of the shear-induced structural transitions have
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44992 (2012)
BACKGROUND: Defects in protein folding may lead to severe degenerative diseases characterized by the appearance of amyloid fibril deposits. Cytotoxicity in amyloidoses has been linked to poration of the cell membrane that may involve interactions wit
Externí odkaz:
https://doaj.org/article/cb48f66acfdd4148aba8ba37f096c1b7
Publikováno v:
Journal of molecular recognition : JMR. 30(3)
Toxicity in amyloidogenic protein misfolding disorders is thought to involve intermediate states of aggregation associated with the formation of amyloid fibrils. Despite their relevance, the heterogeneity and transience of these oligomers have placed
Publikováno v:
Journal of molecular recognition : JMR. 24(6)
Desmin filaments form the intermediate filament system of muscle cells where they play important role in maintaining mechanical integrity and elasticity. Although the importance of desmin elasticity and assembly-disassembly dynamics in cellular mecha
Autor:
Miklós S Z, Kellermayer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 736
The atomic force microscope (AFM) is a high-resolution scanning-probe instrument which has become an important tool for cellular and molecular biophysics in recent years, but lacks the time resolution and functional specificities offered by fluoresce
Publikováno v:
Croatica Chemica Acta
Volume 78
Issue 3
Volume 78
Issue 3
The functionally elastic, I-band part of the myofibrillar protein titin (connectin) contains differentially expressed arrays of serially linked immunoglobulin (Ig)-like domains, the length and composition of which vary among the titin isoforms. The b
Autor:
Miklós S Z, Kellermayer, László, Grama
Publikováno v:
Journal of muscle research and cell motility. 23(5-6)
The details of the global and local structure and function of titin, a giant filamentous intrasarcomeric protein are largely undiscovered. Here we discuss a combination of bulk-solution and novel single-molecule techniques that may lend unique insigh