Výsledky vyhledávání - "Miklós Mándi"

The role of appendectomy and cholecystectomy in the pathogenesis of colorectal carcinomas

Autor: Miklós Mándi, György Keleti, Miklós Juhász

Publikováno v: Annals of Medicine and Surgery

Background Several alterations in the gastrointestinal tract which occur after appendectomy or cholecystectomy have been suggested to raise the risk of developing colorectal carcinoma. Given the frequency that these procedures are performed, we sough

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345ada5aa6e1981604611ef6cd2f080f
https://pubmed.ncbi.nlm.nih.gov/34820118

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Complex Contribution of Cyclophilin D to Ca2+-induced Permeability Transition in Brain Mitochondria, with Relation to the Bioenergetic State

Autor: Csaba Konrad, Judit Doczi, Christos Chinopoulos, Miklós Mándi, Gergely Kiss, Beáta Töröcsik, Szilvia Vajda, Lilla Turiák, Vera Adam-Vizi, Akos A. Gerencser

Publikováno v: Journal of Biological Chemistry. 286:6345-6353

Cyclophilin D (cypD)-deficient mice exhibit resistance to focal cerebral ischemia and to necrotic but not apoptotic stimuli. To address this disparity, we investigated isolated brain and in situ neuronal and astrocytic mitochondria from cypD-deficien

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https://doi.org/10.1074/jbc.m110.196600

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A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+release from mitochondria

Autor: Csaba Konrad, Christos Chinopoulos, Miklós Mándi, Attila Ambrus, Vera Adam-Vizi, Gergely Kiss, Szilvia Vajda

Publikováno v: FEBS Journal. 276:2713-2724

Massive amounts of Ca(2+) can accumulate in mitochondria, owing to its complexation with matrix phosphate. Under conditions in which the mitochondrial uniporter is the foremost pathway for Ca(2+) efflux, the release of sequestered Ca(2+) by protonoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d34c99c282138f7950ea7367c9c98a
https://doi.org/10.1111/j.1742-4658.2009.06995.x

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A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration

Autor: Gergely Kiss, János L. Lábár, Miklós Mándi, Csaba Konrad, Christos Chinopoulos, Beáta Töröcsik, Akos A. Gerencser, Vera Adam-Vizi

Publikováno v: The FEBS journal. 278(5)

Mitochondria isolated from embryos of the crustacean Artemia franciscana lack the Ca(2+)-induced permeability transition pore. Although the composition of the pore described in mammalian mitochondria is unknown, the impacts of several effectors of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2a12d67cfca2bd5f82ff2c54dfff6b
https://pubmed.ncbi.nlm.nih.gov/21205213

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Nicotinic acid adenine dinucleotide phosphate (NAADP) and Ca2+ mobilization

Autor: Judit Bak, Miklós Mándi

Publikováno v: Journal of receptor and signal transduction research. 28(3)

Many physiological processes are controlled by a great diversity of Ca2+ signals that depend on Ca2+ entry into the cell and/or Ca2+ release from internal Ca2+ stores. Ca2+ mobilization from intracellular stores is gated by a family of messengers inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d4d112a9af636e4b9136059c1effd0
https://pubmed.ncbi.nlm.nih.gov/18569524

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Mitochondria from Artemia franciscana embryos exhibit a truncated form of ant, associated with atypical effects of its ligands on Ca2+ uptake capacity and unique morphology of matrix Ca2+ precipitates

Autor: János L. Lábár, Vera Adam-Vizi, Akos A. Gerencser, Beáta Töröcsik, Csaba Konrad, Christos Chinopoulos, Miklós Mándi, Gergely Kiss

Publikováno v: Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797:142-143

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S1.21 Thermodynamic constraints in the reversal of adenine nucleotide translocase during the reversal of F0–F1 ATP synthase caused by respiratory chain inhibition: Critical role of substrate-level phosphorylation

Autor: Miklós Mándi, Katalin Takács, Christos Chinopoulos, Akos A. Gerencser, Lilla Turiák, László Csanády, Vera Adam-Vizi

Publikováno v: Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777:S14

F1ATPase were studied by FT-ESEEM spectroscopy, using Mn(II) as a paramagnetic probe, which replaces the naturally occurring Mg(II) and maintains the enzyme catalytic activity. Purified F1ATPase still containing three endogenous tightly bound nucleot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b2849fb94062c35f80ef1f839581f8
https://doi.org/10.1016/j.bbabio.2008.05.059

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A Novel Kinetic Assay of Mitochondrial ATP-ADP Exchange Rate Mediated by the ANT

Autor: Szilvia Vajda, Christos Chinopoulos, Vera Adam-Vizi, László Csanády, Miklós Mándi, Katalin Mathe

Publikováno v: Biophysical Journal. (6):2490-2504

A novel method exploiting the differential affinity of ADP and ATP to Mg(2+) was developed to measure mitochondrial ADP-ATP exchange rate. The rate of ATP appearing in the medium after addition of ADP to energized mitochondria, is calculated from the

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