Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Mikko P. S. Ares"'
1
Very low density lipoprotein potentiates tumor necrosis factor-α expression in macrophages
Autor: Maria M. Stollenwerk, Gunilla Nordin Fredrikson, Alexandru Schiopu, Mikko P. S. Ares, Wolfgang Dichtl, Jan Nilsson
Publikováno v: Atherosclerosis. 179:247-254
High levels of the triacylglycerol-rich lipoproteins, very low density lipoprotein (VLDL) and intermediate density lipoprotein (IDL) have been identified as independent risk factors for coronary heart disease, and inflammation is thought to contribut
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62de2137bcec5b21b60f65f426687f07
https://doi.org/10.1016/j.atherosclerosis.2004.12.002
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2
Accumulation of LDL in Rat Arteries Is Associated With Activation of Tumor Necrosis Factor-α Expression
Autor: Gunilla Nordin Fredrikson, Jan Nilsson, Audrey Niemann-Jönsson, Stefan Jovinge, Paul Dimayuga, Federico Calara, Mikko P. S. Ares
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 20:2205-2211
Abstract —Activation of vascular inflammation in response to hyperlipidemia is believed to play an important role during the early stages of atherogenesis. We demonstrate here that exposure of cultured, rat aortic smooth muscle cells to low density
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6630a8cb2107ffbe790d3414279667
https://doi.org/10.1161/01.atv.20.10.2205
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3
Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells
Autor: Ingemar Björkhem, L. Juntti-Berggren, Mikko P. S. Ares, Johan Thyberg, M. I. Porn-Ares, P.-O. Berggren, Sten Orrenius, Jan Nilsson, Bengt Kallin, Ulf Diczfalusy
Publikováno v: Journal of Lipid Research, Vol 38, Iss 10, Pp 2049-2061 (1997)
Karolinska Institutet
Europe PubMed Central
Scopus-Elsevier
We have characterized the death of human aortic smooth muscle cells induced by 25-hydroxycholesterol, an oxidation product of cholesterol. Chromatin condensation characteristic of apoptosis was observed by enzymatic (TUNEL) staining of chromatin, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3283e78fcd0a5bd10903fda63809b39
http://www.sciencedirect.com/science/article/pii/S0022227520371352
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4
Retinoic acid inhibits nitric oxide synthase-2 expression through the retinoic acid receptor-alpha
Autor: Mikko P. S. Ares, Ulrich Förstermann, Göran K. Hansson, Allan Sirsjö, Hans Törmä, Anneli Olsson, Andreas C. Gidlöf, Hartmut Kleinert
Publikováno v: Biochemical and biophysical research communications. 270(3)
Retinoids are multipotent modulators of cellular functions and suppress cytokine-induced production of nitric oxide (NO) in several cell types. We have explored the mechanisms by which retinoic acid (RA) regulates NO production in rat aortic smooth m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8d5a5ac97d6cf33760753ec6b8323f
https://pubmed.ncbi.nlm.nih.gov/10772914
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5
Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-kappa B in human vascular smooth muscle cells
Autor: Jan Nilsson, Mikko P. S. Ares, Bengt Kallin, Per Eriksson
Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 15(10)
Abstract Oxidized LDL (Ox-LDL) has been implicated in the development of atherosclerotic lesions, mainly due to its enhanced uptake by macrophages and its ability to alter gene expression in arterial cells. In the present study we demonstrated that O
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63020f1d4f23f68816edee857a00e23c
https://pubmed.ncbi.nlm.nih.gov/7583531
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8
In vivo stimulation of vascular plasminogen activator inhibitor-1 production by very low-density lipoprotein involves transcription factor binding to a VLDL-responsive element
Autor: Wolfgang Dichtl, Mikko P. S. Ares, Per Eriksson, Cecilia M. Giachelli, Marta Scatena, Jan Nilsson, Anders Hamsten, Maria M Stollenwerk
Publikováno v: Europe PubMed Central
Karolinska Institutet
SummaryHigh plasma levels of plasminogen activator inhibitor-1 (PAI-1) are associated with an increased risk of cardiovascular disease. There is also a close relation between high plasma levels of PAI-1 and hypertriglyceridemia. Cell culture studies
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b377c332c63f3245674c373e1aa6c296
http://europepmc.org/abstract/med/11057874
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