Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Mikko Ora"'
Autor:
Farid A. Siddiqui, Catharina Alam, Petja Rosenqvist, Mikko Ora, Ahmed Sabt, Ganesh babu Manoharan, Lakshman Bindu, Sunday Okutachi, Marie Catillon, Troy Taylor, Omaima M. Abdelhafez, Harri Lönnberg, Andrew G. Stephen, Anastassios C. Papageorgiou, Pasi Virta, Daniel Abankwa
Publikováno v:
ACS Omega, Vol 5, Iss 1, Pp 832-842 (2019)
Externí odkaz:
https://doaj.org/article/3c425549098741d9ab67574c49453cfb
Publikováno v:
Catalysts, Vol 10, Iss 2, p 219 (2020)
The potential of Hg(II), a metal ion so-far overlooked in the development of artificial nucleases, to cleave RNA and DNA has been assessed. Accordingly, Hg(II)-promoted cleavage and isomerization of the RNA model compound adenylyl-3′,5′-(2′,3
Externí odkaz:
https://doaj.org/article/4b7f6db832fa4a469488e3abc968d715
Publikováno v:
ARKIVOC, Vol 2012, Iss 5, Pp 226-243 (2012)
Externí odkaz:
https://doaj.org/article/7a1d5219fd84432e8d40353a2882d0e4
Publikováno v:
Molecules, Vol 16, Iss 1, Pp 552-566 (2011)
Thymidine 5´-bis[3-acetyloxy-2-cyano-2-(2-phenylethylcarbamoyl)propyl]phosphate (1) has been prepared and the removal of phosphate protecting groups by hog liver carboxyesterase (HLE) at pH 7.5 and 37 °C has been followed by HPLC. The first detecta
Externí odkaz:
https://doaj.org/article/c54ed4ffd91f43d4a49920828e35c74d
Autor:
Nayera W. Hassan, Ahmed Sabt, Maryam A.Z. El-Attar, Mikko Ora, Alaa El-Din A. Bekhit, Kikuko Amagase, Adnan A. Bekhit, Ahmed S.F. Belal, Perihan A. Elzahhar
Publikováno v:
European Journal of Medicinal Chemistry. 253:115333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc10050cfbf37a107124f07735e141b4
https://doi.org/10.1016/j.ejmech.2023.115333
https://doi.org/10.1016/j.ejmech.2023.115333
Publikováno v:
Chembiochem
A water‐soluble arylmercury complex has been synthesized, and its ability to catalyze the cleavage of the phosphodiester linkage of the RNA model compound adenylyl‐3′,5′‐(2′,3′‐O‐methyleneadenosine) has been assessed over a pH range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c6b36f635c51fdb7d6da4048819c11
https://doi.org/10.1002/cbic.202000799
https://doi.org/10.1002/cbic.202000799
Publikováno v:
ChemistrySelect. 6:488-493
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb36f6cfd5511e3f49105ec35c3d4809
https://doi.org/10.1002/slct.202004426
https://doi.org/10.1002/slct.202004426
Autor:
Andrew G. Stephen, Farid Ahmad Siddiqui, Lakshman Bindu, Pasi Virta, Ganesh babu Manoharan, Mikko Ora, Marie Catillon, Catharina Alam, Daniel Abankwa, Omaima M. Abdelhafez, Anastassios C. Papageorgiou, Sunday Ojochegbe Okutachi, Ahmed Sabt, Harri Lönnberg, Petja Rosenqvist, Troy Taylor
Publikováno v:
ACS Omega, Vol 5, Iss 1, Pp 832-842 (2019)
ACS Omega
ACS Omega
The trafficking chaperone PDE6D (also referred to as PDEδ) has been nominated as a surrogate target for K-Ras4B (hereafter K-Ras). Arl2-assisted unloading of K-Ras from PDE6D in the perinuclear area is significant for correct K-Ras localization and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b5957fbf81865a2193360846f5684d
https://doaj.org/article/3c425549098741d9ab67574c49453cfb
https://doaj.org/article/3c425549098741d9ab67574c49453cfb
Publikováno v:
European Journal of Organic Chemistry. 2015:5004-5012
Phosphoramidates 1 and 2 were synthesized by H-phosphonate methodology and subsequent oxidative amination with L-alanine methyl ester. The removal of the protecting groups at pH = 7.5 and 37 °C in the absence and presence of porcine liver esterase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::126b4789d3cfdb9b0aeb9208cc895e39
https://doi.org/10.1002/ejoc.201500531
https://doi.org/10.1002/ejoc.201500531
Publikováno v:
European Journal of Organic Chemistry. 2015:389-394
Appropriately protected structurally modified nucleoside 3′,5′-cyclic monophosphates are known to show antiviral activity. For this reason, a straightforward synthesis of nucleoside 3′,5′-cyclic phosphates protected with three different enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58dbd669737b6c1aec1623aa894c7a89
https://doi.org/10.1002/ejoc.201403227
https://doi.org/10.1002/ejoc.201403227