Výsledky vyhledávání - "Mikko Juhani Rönty"

Comparison of Targeted Next-Generation Sequencing (NGS) and Real-Time PCR in the Detection ofEGFR,KRAS,andBRAFMutations on Formalin-Fixed, Paraffin-Embedded Tumor Material of Non-Small Cell Lung Carcinoma-Superiority of NGS

Autor: Katja Tuononen, Satu Mäki-Nevala, Aino I. Telaranta-Keerie, Sari Hannula, Virinder Kaur Sarhadi, Mikko Juhani Rönty, Kaisa Salmenkivi, Aija Knuuttila, Sonja Lagström, Pekka Ellonen, Aino Wirtanen, Jenny M. Andrews, Sakari Knuutila

Publikováno v: Genes, Chromosomes and Cancer. 52:503-511

The development of tyrosine kinase inhibitor treatments has made it important to test cancer patients for clinically significant gene mutations that influence the benefit of treatment. Targeted next-generation sequencing (NGS) provides a promising me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a918cf93f24c032bed3624d213483f39
https://doi.org/10.1002/gcc.22047

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The histopathology of idiopathic pulmonary fibrosis in West Highland white terriers shares features of both non-specific interstitial pneumonia and usual interstitial pneumonia in man

Autor: Cécile Clercx, Liisa Lilja-Maula, H.P. Heikkilä, Pernilla Syrjä, Minna M. Rajamäki, Michael J. Day, Mikko Juhani Rönty, Emilie Krafft, Marjukka Myllärniemi

Publikováno v: Journal of comparative pathology. 149(2-3)

Idiopathic pulmonary fibrosis (IPF) in West Highland white terriers (WHWTs) is a breed-related, spontaneously arising disease that is a potential animal model for IPF in man. Histopathological similarity between IPF in WHWTs and usual interstitial pn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b094baecfca2ab8b6f22d0e77224f69c
https://pubmed.ncbi.nlm.nih.gov/23664319

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Cell culture model predicts human disease: Altered expression of junction proteins and matrix metalloproteinases in cervical dysplasia

Autor: Eeva Auvinen, Jussi Tarkkanen, Mikko Juhani Rönty, Niina Kivi, Petri Auvinen

Publikováno v: BMC Clinical Pathology, Vol 12, Iss 1, p 9 (2012)
BMC Clinical Pathology

Background Cervical cancer is necessarily caused by human papillomaviruses, which encode three oncogenes manifesting their functions by interfering with a number of cellular proteins and pathways: the E5, E6, and E7 proteins. We have earlier found in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a6a256e72181cb54e642bf2ae4cc8c
http://www.biomedcentral.com/1472-6890/12/9

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Distribution and levels of alpha-1-antitrypsin in the lung and plasma in smokers and chronic obstructive pulmonary disease

Autor: Anna Linja-aho, Steffen Ohlmeier, Mikko Juhani Rönty, Vuokko L. Kinnula, Tuula Toljamo, Witold Mazur, Pentti Nieminen

Publikováno v: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 121(1)

Our recent non-biased proteomic screening study revealed elevated SerpinA1 i.e. alpha-1-antitrypsin (AAT) levels in induced sputum of smokers with Chronic obstructive pulmonary disease (COPD). This study was designed to further investigate the role o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26498f1e12080c6ad1b28b99a4f4483f
https://pubmed.ncbi.nlm.nih.gov/23030783

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Gremlin-1 associates with fibrillin microfibrils in vivo and regulates mesothelioma cell survival through transcription factor slug

Autor: L. Murray, Olli Ritvos, Outi Leppäranta, Risto Renkonen, Alexander P. Wohl, Katri Koli, Jenni A. Tamminen, Mikko Juhani Rönty, Sakari Joenväärä, Markku Varjosalo, Marjukka Myllärniemi, Gerhard Sengle, Ville Parviainen

Publikováno v: Oncogenesis

Malignant mesothelioma is a form of cancer that is highly resistant to conventional cancer therapy for which no major therapeutic advances have been introduced. Here, we identify gremlin-1, a known bone morphogenetic protein inhibitor crucial for emb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd8674d947f455cfcbed5403fdfcd87
https://doi.org/10.1038/oncsis.2013.29

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Identification and Validation of Human Papillomavirus Encoded microRNAs

Autor: Lars Paulin, Eeva Auvinen, Jussi Tarkkanen, Jarmo Ritari, Kui Qian, Mikko Juhani Rönty, Mikko J. Frilander, Frederic Michon, Petri Auvinen, Tuuli Pietilä

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e70202 (2013)
PLoS ONE

We report here identification and validation of the first papillomavirus encoded microRNAs expressed in human cervical lesions and cell lines. We established small RNA libraries from ten human papillomavirus associated cervical lesions including canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a883a2727a6a61f8b3e302b75f7650
https://doi.org/10.1371/journal.pone.0070202

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The histopathology of idiopathic pulmonary fibrosis in West Highland white terriers – a comparison to usual interstitial pneumonia and nonspecific interstitial pneumonia in man

Autor: Heikkilä, Henna P., Pernilla Elisabet Sofia Syrjä, Mikko Juhani Rönty, Liisa Iiris Onerva Lilja-Maula, Emilie Krafft, Cecile Clercx, Marjukka Myllã¤rniemi, L., Minna Marjaana Rajamäki

Publikováno v: University of Helsinki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6da6c80f54739a7f256d6ad4eee7c87e
https://researchportal.helsinki.fi/en/publications/871c6759-5aae-4473-8571-773edfb530c8

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The histopathology of idiopathic pulmonary fibrosis in West Highland white terriers shares features of both human usual interstitial pneumonia and human nonspecific interstitial pneumonia

Autor: Heikkilä, Henna P., Pernilla Elisabet Sofia Syrjä, Mikko Juhani Rönty, Liisa Iiris Onerva Lilja-Maula, Marjukka Myllã¤rniemi, L., Minna Marjaana Rajamäki

Publikováno v: University of Helsinki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::230dd1996d9d5c1aea3023b39f95e50f
https://researchportal.helsinki.fi/en/publications/dbbcb276-7612-4df0-bedf-3b5e9d47f5f5

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