Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mikko Haanpää"'
Autor:
Feng Wang, Eline Eikeland, Randi J. Reidunsdatter, Lars Hagen, Monica J. Engstrøm, Jürgen Geisler, Mikko Haanpää, Esa Hämäläinen, Guro F. Giskeødegård, Tone F. Bathen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionSystemic and local steroid hormone levels may function as novel prognostic and predictive biomarkers in breast cancer patients. We aimed at developing a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simult
Externí odkaz:
https://doaj.org/article/305a8c0db112429886fe7c585347b0bb
Autor:
Alexandra Robciuc, Hanna Savolainen-Peltonen, Mikko Haanpää, Jukka A. O. Moilanen, Tomi S. Mikkola
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14864 (2022)
The marked sexual dimorphism prevalent in inflammatory/autoimmune diseases is mostly due to sex hormone actions. One common eye disease that disproportionately affects women is dry eye. Thus, our aim was to optimise our highly sensitive liquid chroma
Externí odkaz:
https://doaj.org/article/311d5174d26e4bb4984449ffad0b290d
Autor:
Maria Faltinova, Leena Vehmanen, Heli Lyytinen, Mikko Haanpää, Esa Hämäläinen, Aila Tiitinen, Carl Blomqvist, Johanna Mattson
Purpose To analyze serum estradiol (E2) and estrone (E1) during letrozole treatment and their association to Quality of life (QoL) and side-effects. Methods Postmenopausal breast cancer patients starting adjuvant letrozole were eligible. Serum sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ac3d056b8391ed5cb2253006850a9ae
https://doi.org/10.21203/rs.3.rs-2743799/v1
https://doi.org/10.21203/rs.3.rs-2743799/v1
Autor:
Heli Lyytinen, Johanna Mattson, Leena Vehmanen, Aila Tiitinen, Carl Blomqvist, Maria Faltinova, Mikko Haanpää, Esa Hämäläinen
Publikováno v:
Breast Cancer Research and Treatment. 187:769-775
To analyze whether monitoring serum estradiol (E2) levels using a highly sensitive and specific liquid chromatography tandem mass spectrometry (LC–MS/MS) method may identify patients with AI failure with E2 levels below the lower limit of quantific
Autor:
Hanna Savolainen-Peltonen, Ursula Turpeinen, Esa Hämäläinen, Tomi S. Mikkola, Matti J. Tikkanen, Natalia Hetemäki, Veera Vihma, Feng Wang, Mikko Haanpää
Objective: Although the ovaries produce the majority of estrogens in women before menopause, estrogen is also synthesized in peripheral tissues such as adipose tissue (AT). The typical female AT distribution, concentrated in subcutaneous and femoro-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6288cbee6d2cc64cf7415372239648d3
http://hdl.handle.net/10138/330826
http://hdl.handle.net/10138/330826
Autor:
Mária, Faltinová, Leena, Vehmanen, Heli, Lyytinen, Mikko, Haanpää, Esa, Hämäläinen, Aila, Tiitinen, Carl, Blomqvist, Johanna, Mattson
Publikováno v:
Breast cancer research and treatment. 187(3)
To analyze whether monitoring serum estradiol (E2) levels using a highly sensitive and specific liquid chromatography tandem mass spectrometry (LC-MS/MS) method may identify patients with AI failure with E2 levels below the lower limit of quantificat
Autor:
Tomi S. Mikkola, Matti J. Tikkanen, Hanna Savolainen-Peltonen, Mikko Haanpää, Esa Hämäläinen, Marjut Leidenius, Feng Wang, Veera Vihma, Ursula Turpeinen
Circulating estrogens fluctuate during the menstrual cycle but it is not known whether this fluctuation is related to local hormone levels in adipose tissue. We analyzed estrogen concentrations and gene expression of estrogen-regulating enzymes in br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06ceb594a7af87dafbcd08f86b99df6
http://hdl.handle.net/10138/309238
http://hdl.handle.net/10138/309238
Autor:
Hanna Paatela, Feng Wang, Esa Hämäläinen, Hanna Savolainen-Peltonen, Mikko Haanpää, Tomi S. Mikkola, Matti J. Tikkanen, Natalia Hetemäki, Ursula Turpeinen, Veera Vihma
Publikováno v:
The Journal of clinical endocrinology and metabolism. 102(12)
ContextIn postmenopausal women, adipose tissue (AT) levels of estrogens exceed circulating concentrations. Although increased visceral AT after menopause is related to metabolic diseases, little is known about differences in estrogen metabolism betwe
Publikováno v:
Clinica Chimica Acta. 413:594-599
Background Salivary steroid measurements have the potential to provide a non-invasive assessment of serum free steroid concentrations. Salivary testing has been proposed as a possible substitute for serum testing partly because of easy sample collect