Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mikkel Skjoldan Svenningsen"'
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033072 (2024)
Bacterial persistence is a phenomenon where a subpopulation of cells can survive antibiotic treatment, and it is often linked to extremely slow growth or a dormant state. However, the mechanisms and factors that govern dormancy are not well understoo
Externí odkaz:
https://doaj.org/article/78bd49ae757740e0bbbdc54e8454aec3
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
ABSTRACT The cell-to-cell heterogeneity in a bacterial population provides a rich response to environmental changes and robust survival of an isogenic population. Especially, the rare, extreme phenotypes can be important for survival under transient
Externí odkaz:
https://doaj.org/article/b4cfb303a7374519ae11fcf279ef268d
Publikováno v:
Svenningsen, M S, Svenningsen, S L, Sørensen, M A & Mitarai, N 2022, ' Existence of log-phase Escherichia coli persisters and lasting memory of a starvation pulse ', Life Science Alliance, vol. 5, no. 2, e202101076 . https://doi.org/10.26508/lsa.202101076
The vast majority of a bacterial population is killed when treated with a lethal concentration of antibiotics. The time scale of this killing is often comparable with the bacterial generation time before the addition of antibiotics. Yet, a small subp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40dcd51dbcabcb960008850df6d2e34
https://curis.ku.dk/ws/files/286842935/Existence_of_log_phase_Escherichia_coli_persisters_and_lasting_memory_of_a_starvation_pulse.pdf
https://curis.ku.dk/ws/files/286842935/Existence_of_log_phase_Escherichia_coli_persisters_and_lasting_memory_of_a_starvation_pulse.pdf
Autor:
Mikkel Skjoldan, Svenningsen, Sine Lo, Svenningsen, Michael Askvad, Sørensen, Namiko, Mitarai
Publikováno v:
Life Science Alliance
The authors characterize the growth condition dependence of survival of bacteria exposed to lethal antibiotics for a week. 1-h starvation pulse is shown to cause an increase in survival for days.
The vast majority of a bacterial population is ki
The vast majority of a bacterial population is ki
The vast majority of a bacterial population is quickly killed when treated with a lethal concentration of antibiotics. The time scale of this killing is often comparable with the bacterial generation time before addition of antibiotics. Yet, a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e5bfc7e48ef0bee86790dbb3b03cf86
https://doi.org/10.1101/2020.09.17.301598
https://doi.org/10.1101/2020.09.17.301598
Autor:
Szabolcs Semsey, Namiko Mitarai, Alexandra Veress, Mikkel Skjoldan Svenningsen, Alexander Harms
Publikováno v:
Scientific Reports
Scientific Reports, 9 (1)
Svenningsen, M S, Veress, A, Harms, A, Mitarai, N & Semsey, S 2019, ' Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells ', Scientific Reports, vol. 9, 6056 . https://doi.org/10.1038/s41598-019-42403-7
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, 9 (1)
Svenningsen, M S, Veress, A, Harms, A, Mitarai, N & Semsey, S 2019, ' Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells ', Scientific Reports, vol. 9, 6056 . https://doi.org/10.1038/s41598-019-42403-7
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Transient antibiotic treatment typically eradicates most sensitive bacteria except a few survivors called persisters. The second messenger (p)ppGpp plays a key role in persister formation in Escherichia coli populations but the underlying mechanisms