Data from Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome–Positive C3 Cancers in Mice

Autor: Peter Johannes Holst, Ralf Wagner, Benedikt Asbach, Christian Thirion, Cordula Pertl, Silke Schrödel, Mikkel Dons Müller, Torsten Willert, Patrick Neckermann, Ditte Rahbæk Boilesen

Human papillomavirus (HPV) infections are the main cause of cervical and oropharyngeal cancers. As prophylactic vaccines have no curative effect, an efficient therapy would be highly desired. Most therapeutic vaccine candidates target only a small su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e3af5e14b661d64ac5a9e542fe4157
https://doi.org/10.1158/2326-6066.c.6551147.v1

A Systematic Review of Expression and Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches

Autor: Karen Nørgaard Nielsen, Mikkel Dons Müller, Peter Johannes Holst

Publikováno v: Müller, M D, Holst, P J & Nielsen, K N 2022, ' A systematic review of expression and immunogenicity of human endogenous retroviral proteins in cancer and discussion of therapeutic approaches ', International Journal of Molecular Sciences, vol. 23, no. 3, pp. 1330 . https://doi.org/10.3390/ijms23031330
International Journal of Molecular Sciences, Vol 23, Iss 1330, p 1330 (2022)

Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that have become fixed in the human genome. While HERV genes are typically silenced in healthy somatic cells, there are numerous reports of HERV transcription and tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f3f362eb0c1de359c48f00f5eda9a4
https://pubmed.ncbi.nlm.nih.gov/35163254