Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mikkel B Schuster"'
Autor:
Marie S Hasemann, Felicia K B Lauridsen, Johannes Waage, Janus S Jakobsen, Anne-Katrine Frank, Mikkel B Schuster, Nicolas Rapin, Frederik O Bagger, Philipp S Hoppe, Timm Schroeder, Bo T Porse
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004079 (2014)
Transcription factors are key regulators of hematopoietic stem cells (HSCs) and act through their ability to bind DNA and impact on gene transcription. Their functions are interpreted in the complex landscape of chromatin, but current knowledge on ho
Externí odkaz:
https://doaj.org/article/cd6fa19cee4f46d1a7dc8f2a86cd50fa
Autor:
Marie S Hasemann, Mikkel B Schuster, Anne-Katrine Frank, Kim Theilgaard-Mönch, Thomas Å Pedersen, Claus Nerlov, Bo T Porse
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38841 (2012)
BackgroundTranscription factors play a key role in lineage commitment and differentiation of stem cells into distinct mature cells. In hematopoiesis, they regulate lineage-specific gene expression in a stage-specific manner through various physical a
Externí odkaz:
https://doaj.org/article/435adf3ec52b4d42a64f1396f579cd8c
Autor:
Elizabeth Heyes, Anna S. Wilhelmson, Anne Wenzel, Gabriele Manhart, Thomas Eder, Mikkel B. Schuster, Edwin Rzepa, Sachin Pundhir, Teresa D’Altri, Anne-Katrine Frank, Coline Gentil, Jakob Woessmann, Erwin M. Schoof, Manja Meggendorfer, Jürg Schwaller, Torsten Haferlach, Florian Grebien, Bo T. Porse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The myeloid transcription factor CEBPA is recurrently biallelically mutated (i.e., double mutated; CEBPA DM) in acute myeloid leukemia (AML) with a combination of hypermorphic N-terminal mutations (CEBPA NT), promoting expression of the leuk
Externí odkaz:
https://doaj.org/article/015f842398434c8ab9d3b64437bd9772
Autor:
Teresa D'Altri, Anna S. Wilhelmson, Mikkel B. Schuster, Anne Wenzel, Adrija Kalvisa, Sachin Pundhir, Anne Meldgaard Hansen, Bo T. Porse
Publikováno v:
Haematologica, Vol 106, Iss 4 (2020)
ASXL1 is one of the most commonly mutated genes in myeloid malignancies, including Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). In order to further our understanding of the role of ASXL1 lesions in malignant hematopoiesis, we gene
Externí odkaz:
https://doaj.org/article/c4c6b7af43844ae1b96e43eafb07c0cb
Autor:
Elizabeth Heyes, Anna S. Wilhelmson, Anne Wenzel, Gabriele Manhart, Thomas Eder, Mikkel B. Schuster, Edwin Rzepa, Sachin Pundhir, Teresa D’Altri, Coline Gentil, Manja Meggendorfer, Jürg Schwaller, Torsten Haferlach, Florian Grebien, Bo T. Porse
The myeloid transcription factor CEBPA is recurrently biallelically mutated (i.e., double mutated;CEBPADM) in acute myeloid leukemia (AML) with a combination of hypermorphic N-terminal mutations (CEBPANT), promoting expression of the leukemia-associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33ec7f896c881ee6889222b0683e4e87
https://doi.org/10.1101/2023.03.28.534511
https://doi.org/10.1101/2023.03.28.534511
