Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mikito Kikumori"'
Effects of rearing conditions on aging characteristics and pathobiological phenotypes in SAMP10 mice
Autor:
Mikito Kikumori, Tsukao Nishimori, Takayoshi Nishimura, Toshio Takeda, Shigenori Furukawa, Shiori Araki, Atsuyoshi Shimada
Publikováno v:
International Congress Series. 1260:315-319
The purpose of this study was to obtain background data regarding aging characteristics and pathobiological phenotypes in SAMP10/Ta (P10) and SAMR1TA (R1) mice reared under specific pathogen-free (SPF) conditions and compare the data with those of P1
Autor:
Jiro Fujimoto, Ryuichi Morishita, N Tsuboniwa, Akihiko Okuyama, Tadamichi Hirano, Yasufumi Kaneda, Shigenori Furukawa, Mikito Kikumori
Publikováno v:
Human Gene Therapy. 12:469-487
We tested, in cynomolgus monkeys, the safety and effectiveness of a hybrid liposome vector, hemagglutinating virus of Japan (HVJ)--artificial viral envelope (AVE) liposomes, for human therapeutic gene transfer in a series of experiments. In a repetit
Autor:
Tsukao Nishimori, Nobuyoshi Sumi, Shigenori Furukawa, Seitaro Ishibashi, Yuzou Taniguchi, Hachiro Kouyama, Keiko Wakura, Mikito Kikumori
Publikováno v:
The Journal of Toxicological Sciences. 22:93-124
Oral single-dose and 13-week repeat-dose toxicity studies of (+/-)-4-ethylamino-1, 1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride (RCC-36), an active metabolite of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyc
Autor:
Tagahiko Morinaga, Kimio Yasuhira, Masataka Watanabe, Yasuhiro Shindo, Nobuyoshi Sumi, Shigenori Furukawa, Shigenobu Fujii, Mikito Kikumori
Publikováno v:
The Journal of Toxicological Sciences. 21:187-206
A study of the effect of prulifloxacin, a new antibacterial agent, during the period of organogenesis was conducted in Sprague-Dawley rats. Female rats were given prulifloxacin orally at dose levels of 0 (control), 30, 300, and 3000 mg/kg from day 7
Autor:
Tagahiko Morinaga, Shigenobu Fujii, Kimio Yasuhira, Mikito Kikumori, Yasuhiro Shindo, Masataka Watanabe, Shigenori Furukawa, Nobuyoshi Sumi
Publikováno v:
The Journal of Toxicological Sciences. 21:207-217
A study of the effect of prulifloxacin, a new antibacterial agent, during the period of organogenesis was conducted in New Zealand White rabbits. Female rabbits were given prulifloxacin orally at dose levels of 0 (control), 10, 30 and 100 mg/kg from
Autor:
Mikito Kikumori, Tsukao Nishimori, Ikuo Nishida, Seitaro Ishibashi, Shigenori Furukawa, Yuzou Taniguchi, Nobuyoshi Sumi, Keiko Iwakura
Publikováno v:
The Journal of Toxicological Sciences. 20:237-257
A repeated dose toxicity study of montirelin hydrate (NS-3), a new drug for the treatment of disturbance of consciousness, was conducted in beagle dogs. Male and female dogs were given the drug intravenously for 26 weeks at doses of 0 (control), 0.02
Autor:
Shigenori Furukawa, Tagahiko Morinaga, Kimio Yasuhira, Shigenobu Fujii, Masataka Watanabe, Nobuyoshi Sumi, Mikito Kikumori
Publikováno v:
The Journal of Toxicological Sciences. 20:259-275
A study of fertility and early embryonic development to implantation of montirelin hydrate (NS-3), a new drug for the treatment of disturbance of consciousness, was conducted in Sprague-Dawley rats. Male rats were given the drug intravenously from 63
Autor:
Kimio Yasuhira, Mikito Kikumori, Toshiaki Aoyama, Motoyoshi Kojima, Yukio Hashimoto, Ryousuke Kiwata, Ikuo Nishida, Tadahisa Shimoda, Takashi Yamamoto
Publikováno v:
International Journal of Toxicology. 13:19-37
Autor:
Mikito Kikumori, Takashi Yamamoto, Yukio Hashimoto, Masanori Takeuchi, Ryousuke Kiwata, Kimio Yasuhira, Ikuo Nishida, Tadahisa Shimoda
Publikováno v:
International Journal of Toxicology. 13:10-18
Autor:
Masataka Watanabe, Nobuyoshi Sumi, Yasuhiro Shindo, Shigenobu Fujii, Kimio Yasuhira, Tagahiko Morinaga, Mikito Kikumori, Shigenori Furukawa
Publikováno v:
The Journal of toxicological sciences. 21
A peri- and postnatal study of prulifloxacin, a new antibacterial agent, was conducted in Sprague-Dawley rats. Female rats were given prulifloxacin orally at dose levels of 0 (control), 30, 100 and 300 mg/kg from day 17 of pregnancy to day 21 after d