Výsledky vyhledávání - "Mikio Terabayashi"

[Reproductive and developmental toxicity study of 6-amidino-2-naphthyl 4(-)[(4,5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187). (II)--Oral administration to rats during the period of fetal organogenesis (prenatal examination)

Autor: Yasuki Yokomoto, Kazuyoshi Watanabe, Keitaro Terazawa, Akira Maruden, Norio Hasegawa, Mikio Terabayashi, Shigeru Kuramoto, Kazunori Shimamura, Kyoko Otani

Publikováno v: The Journal of toxicological sciences. 17

6-Amidino-2-naphthyl 4(-)[(4,5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187) was given orally to pregnant Crj : CD (Sprague-Dawley) rats from days 7 through 17 of gestation at dose levels of 50, 200 and 800 mg/kg/day. In the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970816d1f17087a501b20c31d94c1387
https://pubmed.ncbi.nlm.nih.gov/1369754

Zobrazit plný text záznamu

[Antigenicity study of 6-amidino-2-naphthyl 4(-)[(4,5-dihydro-1H-imidazol-2-yl)amino] benzoate dimethanesulfonate (FUT-187) in guinea pigs and mice

Autor: Akinobu Ouchida, Mikio Terabayashi, Kazunori Shimamura, Shigeru Kuramoto, Kyoko Otani, Keitaro Terazawa, Minoru Oda

Publikováno v: The Journal of toxicological sciences. 17

Antigenicity study of 6-amidino-2-naphthyl 4-[(4, 5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187), a new protease inhibitor, was investigated in guinea pigs and mice and the following results were obtained. 1. In guinea pigs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212784628fcce84b54350daf580b4066
https://pubmed.ncbi.nlm.nih.gov/1296027

Zobrazit plný text záznamu

[Reproductive and developmental toxicity studies of 6-amidino-2-naphthyl 4(-)[(4,5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187). (IV)--Oral administration to New Zealand white rabbits during the period of fetal organogenesis

Autor: Keitaro Terazawa, Kazunori Shimamura, Mikio Terabayashi, Shigeru Kuramoto, Akira Maruden, Norio Hasegawa

Publikováno v: The Journal of toxicological sciences. 17

Oral administration of 6-amidino-2-naphthyl 4(-)[(4,5-dihydro-1H-imidazol-2-yl)amino] benzoate dimethanesulfonate (FUT-187) at doses of 10, 30 and 100 mg/kg was given to New Zealand White rabbits on days 6 to 18 of gestation. The following results we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f65eceb3f94c139a690b3e234f3144
https://pubmed.ncbi.nlm.nih.gov/1369755

Zobrazit plný text záznamu

[Acute toxicity study of 6-amidino-2-naphthyl 4-[(4,5-dihydro-1H-imidazol-2-yl) amino] benzoate dimethanesulfonate (FUT-187) in mice, rats and dogs

Autor: Keitaro Terazawa, Kyoko Otani, Shigeru Kuramoto, Mikio Terabayashi, Yasuki Yokomoto, Kazuyoshi Watanabe, Kazunori Shimamura, Kazumasa Yamashita

Publikováno v: The Journal of toxicological sciences. 17

Single oral, subcutaneous or intravenous administration to mice and rats and oral administration to dogs were performed to investigate the acute toxicity of FUT-187. 1) LD50 values in mice were 4, 395 mg/kg for males and 3, 626 mg/kg for females oral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76d5f3365b0ebc2fcd9f5ab4eeca0dd
https://pubmed.ncbi.nlm.nih.gov/1296019

Zobrazit plný text záznamu

Induction of hydrocephalus and alterations in motor functional development by maternal ethylenethiourea exposure in rat offsprings

Autor: Norio Hasegawa, Takuo Aoyama, Mitsunobu Fujita, Mikio Terabayashi, Masahiro Iwaki

Publikováno v: Japanese Journal of Pharmacology. 32:287

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::434735c920f6c05158ad0c4721819a97
https://doi.org/10.1016/s0021-5198(19)54271-8

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání