Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mikio Morishima"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 301-307 (2008)
Block of cardiac hERG K+ channels by the antihistamine terfenadine and the prokinetic agent cisapride is associated with prolonged ventricular repolarization and an increased risk of ventricular arrhythmia. Here, we used a site-directed mutagenesis a
Externí odkaz:
https://doaj.org/article/aa6361ba0fbe4b19a889f266cab50d81
Publikováno v:
Cardiovascular Research. 98:136-144
Aims Na+ channel blockers are often used to treat atrial fibrillation (AF), but may sometimes cause ventricular contractile dysfunction. However, amiodarone, a multi-channel blocker with Na+ channel block, causes less contractile dysfunction. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::640e44cd82745ae80c2ec38c85bcdafc
https://doi.org/10.1093/cvr/cvt007
https://doi.org/10.1093/cvr/cvt007
Publikováno v:
Macromolecules. 31:7764-7769
This paper presents a new class of nonlinear optical (NLO) polyimide for second harmonic generation (SHG). This new class of NLO polyimide consists of 2,4-diamino-4‘-nitroazobenzene (2R-DIAMINE) wi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eeb56d7c0085ac6e50c0b9c8fe12d58
https://doi.org/10.1021/ma9803436
https://doi.org/10.1021/ma9803436
Autor:
Hiroki Takanari, Tomoyuki Suzuki, Masahide Harada, Haruo Honjo, Masatoshi Yamazaki, Ichiro Sakuma, Yuko S. Ishiguro, Tobias Opthof, Kaichiro Kamiya, Harumichi Nakagawa, Itsuo Kodama, Mikio Morishima, Yusuke Okuno
Publikováno v:
Heart rhythm, 6(5), 684-692. Elsevier
Background Modification of spiral wave (SW) reentry by antiarrhythmic drugs is a central issue to be challenged for better understanding of their benefits and risks. Objective We investigated the effects of pilsicainide and/or verapamil, which block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf2c66b7b077b300c9b7111c445ee6e
https://pure.amc.nl/en/publications/early-termination-of-spiral-wave-reentry-by-combined-blockade-of-na-and-ltype-ca2-currents-in-a-perfused-twodimensional-epicardial-layer-of-rabbit-ventricular-myocardium(aa97a8e9-050b-4d1e-807b-ca380fba3901).html
https://pure.amc.nl/en/publications/early-termination-of-spiral-wave-reentry-by-combined-blockade-of-na-and-ltype-ca2-currents-in-a-perfused-twodimensional-epicardial-layer-of-rabbit-ventricular-myocardium(aa97a8e9-050b-4d1e-807b-ca380fba3901).html
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 301-307 (2008)
Block of cardiac hERG K+ channels by the antihistamine terfenadine and the prokinetic agent cisapride is associated with prolonged ventricular repolarization and an increased risk of ventricular arrhythmia. Here, we used a site-directed mutagenesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fecb1a8d47a436dcd4c8a388c496d6a
https://pubmed.ncbi.nlm.nih.gov/18987434
https://pubmed.ncbi.nlm.nih.gov/18987434
Autor:
Mikio Morishima, Ryoko Niwa, Takahiro Yamaguchi, Sara Kato, Yukiomi Tsuji, Haruo Honjo, Ichiro Sakuma, Kaichiro Kamiya
Publikováno v:
Circulation. 118
Purpose: Nifekalant, a potent and common antiarrhythmic drug, has been regarded to treat reentry arrhythmias through I Kr block (antagonist action). But, recently nifekalant was reported to increase I Kr at slight depolarizing level (agonist action)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e1a47b7e305a4823886f5815955e45
https://doi.org/10.1161/circ.118.suppl_18.s_533-a
https://doi.org/10.1161/circ.118.suppl_18.s_533-a
Autor:
Norihiro Ueda, Tomoyuki Suzuki, Sara Kato, Yoshio Takemoto, Mikio Morishima, Hiroki Takanari, Yukiomi Tsuji, Haruo Honjo, Kaichiro Kamiya
Publikováno v:
Biophysical Journal. (2):133a
Introduction: Na+ channel blockers are usually applied to atrial fibrillation (AF), but may sometimes cause cardiac contractile dysfunction. However, amiodarone, a multi-channel blocker with Na+ channel block, does not induce cardiac dysfunction. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3ea8b7b01489816b1f1c3ba1116743
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