Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mikio Doy"'
Autor:
Akira Honda, Kouwa Yamashita, Mitsuteru Numazawa, Tadashi Ikegami, Mikio Doy, Yasushi Matsuzaki, Hiroshi Miyazaki
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 458-464 (2007)
We describe a highly sensitive and specific method for the quantification of serum 7α-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis. This method is based upon a stable isotope dilution technique by liq
Externí odkaz:
https://doaj.org/article/81ea88173055440883cd2edc253c91ce
Autor:
Akira Honda, Gerald Salen, Yasushi Matsuzaki, Ashok K. Batta, Guorong Xu, Takeshi Hirayama, G. Stephen Tint, Mikio Doy, Sarah Shefer
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 2, Pp 287-296 (2005)
Cerebrotendinous xanthomatosis (CTX), sterol 27-hydroxylase (CYP27A1) deficiency, is associated with markedly reduced chenodeoxycholic acid (CDCA), the most powerful activating ligand for farnesoid X receptor (FXR). We investigated the effects of red
Externí odkaz:
https://doaj.org/article/93d1bd6384294b5fade933663ec32d13
Autor:
Tadashi Ikegami, Toshiya Chiba, Yasushi Matsuzaki, Mikio Doy, Akira Honda, Yoshifumi Saito, Shinji Sugahara, Koichi Tokuuye, Toshiyuki Okumura, Junichi Iwamoto, Hirohiko Tsujii
Publikováno v:
Hepatology Research. 44:403-409
AIM Proton beam therapy is safe and more effective than conventional radiation therapy for the local control of nodular hepatocellular carcinoma (HCC). However, evaluating therapeutic response by imaging is not accurate during the early post-irradiat
Autor:
Tadashi Ikegami, Yasushi Matsuzaki, Takeshi Hirayama, Teruo Miyazaki, Mikio Doy, Yoshifumi Saitoh, Akira Honda, Takashi Hara
Publikováno v:
Hepatology Research. 41:530-541
AIM Infection with hepatitis C virus (HCV) is the leading cause of liver cirrhosis that develops into hepatocellular carcinoma. Previous studies have shown in vitro that lipids within hepatocytes are crucially important for a series of HCV infection-
Autor:
Takeshi Hirayama, Tadashi Ikegami, Takashi Hara, Teruo Miyazaki, Mikio Doy, Akira Honda, Yasushi Matsuzaki, Yoshifumi Saitoh
Publikováno v:
Hepatology Research. 39:664-674
Aim: Although the anti-hepatitis C virus (HCV) antibody test has been recommended to the whole Japanese population, most countries have not implemented it. The present study aims to re-evaluate the usefulness of markers examined in the general health
Autor:
J. Kobayashi, Nobuo Mori, Keiko Tanaka-Taya, Kiyosu Taniguchi, Nobuhiko Okabe, Yasushi Ohkusa, Takaaki Ohyama, Mikio Doy
Publikováno v:
Pediatrics International. 50:464-468
Background The aim of the present study was to produce the first estimation in Japan of the basic reproduction number (R(0)) and the minimum level of vaccine coverage needed to prevent measles outbreaks (P(c)). Methods A questionnaire survey was cond
Publikováno v:
Archives of Virology. 153:945-949
To determine the influence of oseltamivir phosphate (Tamiflu®) on the results of microneutralization and hemagglutinin-inhibition (HI) tests in human sera with H5N2 influenza virus, ten volunteers were administered Tamiflu® and blood samples were c
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 5, Pp 1212-1220 (2007)
We have developed a new sensitive and specific nonradioisotope assay method to measure the activity of HMG-CoA reductase, the rate-controlling enzyme in the cholesterol biosynthetic pathway. This method was based upon a stable isotope dilution techni
Autor:
Mikio Doy, Tadashi Ikegami, Akira Honda, Yasushi Matsuzaki, Kouwa Yamashita, Mitsuteru Numazawa, Hiroshi Miyazaki
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 458-464 (2007)
We describe a highly sensitive and specific method for the quantification of serum 7alpha-hydroxy-4-cholesten-3-one (C4), which has been used as a biomarker for bile acid biosynthesis. This method is based upon a stable isotope dilution technique by
Autor:
Gerald Salen, Teruo Miyazaki, Guorong Xu, Mikio Doy, Michael A. Lea, Takeshi Hirayama, Tadashi Ikegami, Akira Honda, Yasushi Matsuzaki
Publikováno v:
Hepatology. 44:602-611
Hypercholesterolemia is an important paraneoplastic syndrome in patients with hepatoma, but the nature of this defect has not yet been identified. We investigated the molecular mechanisms of hypercholesterolemia in a hepatoma-bearing rat model. Buffa