Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mikimasa Tanada"'
Autor:
Kenichi Nomura, Satoshi Hashimoto, Ryuuichi Takeyama, Minoru Tamiya, Tatsuya Kato, Terushige Muraoka, Mirai Kage, Keiji Nii, Kenichiro Kotake, Satomi Iida, Takashi Emura, Mikimasa Tanada, Hitoshi Iikura
Publikováno v:
Journal of Medicinal Chemistry. 65:13401-13412
Autor:
Kenichi, Nomura, Satoshi, Hashimoto, Ryuuichi, Takeyama, Minoru, Tamiya, Tatsuya, Kato, Terushige, Muraoka, Mirai, Kage, Keiji, Nii, Kenichiro, Kotake, Satomi, Iida, Takashi, Emura, Mikimasa, Tanada, Hitoshi, Iikura
Publikováno v:
Journal of medicinal chemistry. 65(19)
We report a versatile and durable method for synthesizing highly
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:68-72
An equilibrium containing the thiol derivative of Hoechst33258 (Ht-SH), glutathione (G-SH), and the corresponding homo and hetero disulfides was shifted by the addition of the duplex DNA. It was shown from the analysis of the components that the hete
Publikováno v:
The Journal of Organic Chemistry. 71:125-134
[structure: see text] The aim of this study is to develop bidentate minor-groove binders that bind the double binding motifs cooperatively. The new bidentate ligands (1) have been designed by connecting two Hoechst 33258 units with a polyether linker
Autor:
Shigeki Sasaki, Mikimasa Tanada
Publikováno v:
Nucleic acids symposium series (2004). (49)
The aim of this study is to develop new recognition molecules for the DNA higher-ordered structure on the basis of new concept of DNA recognition mode. In order to bind two remote binding sites of DNA at the same time, we designed the new bidentate l
Publikováno v:
Nucleic Acids Symposium Series. 50:161-162
Genome-targeting molecules would have broad application as probes in genomic study. We recently developed the ligands (Bpy-H) connecting the Hoechst33258 skeleton for DNA binding and 2,2'-bipyridine for Cu(2+) complexation. It was shown that L-Bpy-H
Publikováno v:
HETEROCYCLES. 63:29
Small molecules with capability of binding with DNA or RNA would have broad application as probes in genomic studies, and also as potential candidates for new therapeutic agents. In this study, we synthesized dithioamido-bipyrrole derivatives as new