Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Mikiko, Nakamura"'
Autor:
Shun-ichiro Komatsu, Yoko Kayukawa, Yoko Miyazaki, Akihisa Kaneko, Hisashi Ikegami, Takahiro Ishiguro, Mikiko Nakamura, Werner Frings, Natsuki Ono, Kiyoaki Sakata, Toshihiko Fujii, Shohei Kishishita, Takehisa Kitazawa, Mika Endo, Yuji Sano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody recognizing glypican-3 and CD3, is in phase I clinical trials. After a first-in-human clinical trial of an anti-CD28 agonist monoclonal antibody resulting in severe l
Externí odkaz:
https://doaj.org/article/d2beb88677cc4be395bfc5abeda0d963
Autor:
Rika Horii, Masao Honda, Takayoshi Shirasaki, Tetsuro Shimakami, Ryogo Shimizu, Souma Yamanaka, Kazuhisa Murai, Kazunori Kawaguchi, Kuniaki Arai, Tatsuya Yamashita, Yoshio Sakai, Taro Yamashita, Hikari Okada, Mikiko Nakamura, Eishiro Mizukoshi, Shuichi Kaneko
Publikováno v:
Hepatology Communications, Vol 3, Iss 12, Pp 1687-1703 (2019)
The circadian rhythm of the liver plays an important role in maintaining its metabolic homeostasis. We performed comprehensive expression analysis of microRNAs (miRNAs) using TaqMan polymerase chain reaction of liver biopsy tissues to identify the mi
Externí odkaz:
https://doaj.org/article/35a20ba19f9f4e62972cd47b53a3c5b1
Autor:
Shizuka Hozuki, Hideki Yoshioka, Satoshi Asano, Mikiko Nakamura, Saori Koh, Yukihiro Shibata, Yuta Tamemoto, Hiromi Sato, Akihiro Hisaka
Publikováno v:
Clinical Pharmacokinetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49aa04c62d8e649280253738b4c06e1e
https://doi.org/10.1007/s40262-023-01234-6
https://doi.org/10.1007/s40262-023-01234-6
Publikováno v:
Journal of Bioscience and Bioengineering. 133:587-595
Escherichia coli, Saccharomyces cerevisiae, and mammalian culture cells are standard host organisms for genetic engineering and research, thus various plasmid vectors have been developed. However, the vectors are designed only for a single host owing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754aaeb422914e51c9bfebd369a4ecbc
https://doi.org/10.1016/j.jbiosc.2022.03.002
https://doi.org/10.1016/j.jbiosc.2022.03.002
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 3.4MB, Histological assessment of hepatic adenoma, HCC and non-tumor regions of Pdgf-c Tg and WT mouse livers fed with different diets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44cc6fa4915f8627210ac929518061f5
https://doi.org/10.1158/0008-5472.22393725.v1
https://doi.org/10.1158/0008-5472.22393725.v1
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 507K, Heat map of serial gene expression profiling in liver of Pdgf-c Tg mice that developed hepatic fibrosis and tumors. Differentially expressed genes clustered in a one way hierarchical method among seven grouped samples: WT mice at 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c53cb90dc5e5a7484c640b300c3af8
https://doi.org/10.1158/0008-5472.22393722
https://doi.org/10.1158/0008-5472.22393722
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 348K, A: Immunohistochemica l staining of collagen 4, desmin, CD31 and Tie2 expression in Pdgf-c T9 or WT mouse livers fed with basal diet or 0.06% peretinoin. B: Densitometric analysis of CD31 - or CD34-positive areas in liver of Pdgf-c T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0339dd3a6c0be1a035ba8669a2f92e61
https://doi.org/10.1158/0008-5472.22393728.v1
https://doi.org/10.1158/0008-5472.22393728.v1
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 133K, (A) Western blotting of PDGFR-o, POGFR-p, VEGFR2, p-AKT, p-ERK112 and GAPDH expression in Huh-7, HepG2, NH3T3, HLE, HUVEC and Lx-2 cells treated with peretinoin. (B) RTD-peR evaluation of collagen 1a2 in Lx-2, HLE and HUh-7 cells wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59336288200b762342d1dce69a57f07d
https://doi.org/10.1158/0008-5472.22393713
https://doi.org/10.1158/0008-5472.22393713
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 1.5MB, Pathway analysis of differentially expressed genes using MetaCore (GeneGo). Functional ontology enrichment analysis was performed to find differentially expressed pathway using 538 differentially expressed genes in cluster A, B, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f812c71e77b2f72129b914a618c67f6
https://doi.org/10.1158/0008-5472.22393719
https://doi.org/10.1158/0008-5472.22393719
Autor:
Shuichi Kaneko, Nelson Fausto, Takuji Tanaka, Hajime Sunagozaka, Mikiko Nakamura, Riuta Takabatake, Takayoshi Shirasaki, Kazuhiro Hada, Yuuki Takebuchi, Taro Yamashita, Yoshio Sakai, Jean S. Campbell, Masao Honda, Hikari Okada
PDF file - 2MB, The core gene network consisting 41 representative growth factors, receptors (PDGFR and TGFI3R etc) and transcriptional factors. Sp1 and Ap1 could be the "hub", key regulators in the network.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485f52b9a4fae68b93d2d761cd0b4480
https://doi.org/10.1158/0008-5472.22393716.v1
https://doi.org/10.1158/0008-5472.22393716.v1