Zobrazeno 1 - 10
of 356
pro vyhledávání: '"Mikihiko KOGO"'
Autor:
Sou Kawata, Soju Seki, Akira Nishiura, Yoshihiro Kitaoka, Kanako Iwamori, So-ichiro Fukada, Mikihiko Kogo, Susumu Tanaka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) progressively impairs motor neurons, leading to muscle weakness and loss of voluntary muscle control. This study compared the effects of SOD1 mutation on masticatory and limb muscles from disease onset to
Externí odkaz:
https://doaj.org/article/15bc8cc7b58c4a76989606822dc24e8a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The posterior lingual glands are classified as Weber and von Ebner glands. Glycans play an important role in salivary glands. Although the distribution of glycans can explain functional diversity and variation, there are many unknowns in the
Externí odkaz:
https://doaj.org/article/78145e7ac3184e52ac2d876b37197678
Autor:
Emi Fujibayashi, Satomi Mukai, Kosuke Torigata, Yumi Ando, Toshihiro Uchihashi, Masami Nozaki, Susumu Tanaka, Masato Okada, Mikihiko Kogo, Hiroshi Nojima, Norikazu Yabuta
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The epithelial-to-mesenchymal transition (EMT) is a critical process by which cancer cells acquire malignant features. However, the molecular mechanism and functional implications of EMT and the mesenchymal-to-epithelial transition (MET) in
Externí odkaz:
https://doaj.org/article/48e63075d1b2460fa119cc1239c057f1
Autor:
Soju Seki, Yoshihiro Kitaoka, Sou Kawata, Akira Nishiura, Toshihiro Uchihashi, Shin-ichiro Hiraoka, Yusuke Yokota, Emiko Tanaka Isomura, Mikihiko Kogo, Susumu Tanaka
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2967 (2023)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterised by the progressive degeneration of motor neurons, resulting in muscle weakness, paralysis, and, ultimately, death. Presently, no effective treatment for ALS
Externí odkaz:
https://doaj.org/article/28b431bcd21e4a49a347dba8a626ad86
Publikováno v:
Japanese Dental Science Review, Vol 57, Iss , Pp 174-181 (2021)
Wound healing in the oral and maxillofacial region is a complicated and interactive process. Severe mucosal or skeletal muscle injury by trauma or surgery induces worse healing conditions, including delayed wound closure and repair with excessive sca
Externí odkaz:
https://doaj.org/article/6701f485a2914dca8ae1eae083d8bae8
Autor:
Toshihiro Uchihashi, Hirokazu Nakahara, Hiroshi Fukuhara, Miwako Iwai, Hirotaka Ito, Akinari Sugauchi, Minoru Tanaka, Mikihiko Kogo, Tomoki Todo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 388-398 (2021)
The prognosis of oral squamous cell carcinoma (OSCC) largely depends on the control of lymph node metastases. We evaluate the therapeutic efficacy of G47Δ, a third-generation oncolytic herpes simplex virus type 1 (HSV-1), in mouse tongue cancer mode
Externí odkaz:
https://doaj.org/article/5067a5a625a94b2fb44a0680837a8d04
Autor:
Toshihiro Inubushi, Ayaka Fujiwara, Takumi Hirose, Gozo Aoyama, Toshihiro Uchihashi, Naoki Yoshida, Yuki Shiraishi, Yu Usami, Hiroshi Kurosaka, Satoru Toyosawa, Susumu Tanaka, Tetsuro Watabe, Mikihiko Kogo, Takashi Yamashiro
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Cleft palate is one of the major congenital craniofacial birth defects. The etiology underlying the pathogenesis of cleft palate has yet to be fully elucidated. Dissociation of the medial edge epithelium (MEE) at the contacting region of palatal shel
Externí odkaz:
https://doaj.org/article/805075ca0a4a4c0b9d653a0aa7fbbc3a
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0212323 (2021)
Rac proteins, members of the Rho family of small GTP-binding proteins, have been implicated in transducing a number of signals for various biological mechanisms, including cell cytoskeleton organization, transcription, proliferation, migration, and c
Externí odkaz:
https://doaj.org/article/1e1f6e958b1f42e380f0d4ff7f6bb1f3
Autor:
Emiko Tanaka Isomura, DDS, PhD, Kiyoko Nakagawa, DDS, PhD, Ryo Mitsui, DDS, Yosuke Shogen, DDS, PhD, Takeshi Fujita, DDS, PhD, Mikihiko Kogo, DDS, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4, p e2767 (2020)
Background:. When complete recovery of tongue function following tumor excision is desired, reestablishment of the complex movements of the tongue is necessary. However, currently available methods for recovery of tongue function, such as flap surger
Externí odkaz:
https://doaj.org/article/f4cfb7215690409183d60b4324a7b189
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238646 (2020)
BackgroundVelopharyngeal structure augmentation methods are used as alternatives to pharyngeal flap operations. Recently, we investigated the sites of velopharyngeal structure augmentation in dogs and reported that the most effective injection locati
Externí odkaz:
https://doaj.org/article/c2b3cefdea66410cb2ae208b2a22c96e