Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Miki Nakamura"'
Autor:
Ryoko Araki, Yuko Hoki, Tomo Suga, Chizuka Obara, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Satoshi Kamimura, Miki Nakamura, Sayaka Wakayama, Andras Nagy, Teruhiko Wakayama, Masumi Abe
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Point mutations have been found in induced pluripotent stem cells (iPSCs) but when they arise is unclear. Here, the authors show that a G1/S cell cycle checkpoint deficiency transiently occurs early in genome reprogramming, suggesting a common develo
Externí odkaz:
https://doaj.org/article/fead58306cee46a28867f75c35cbe41b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6847 (2022)
Stimulator of Interferon Genes (STING) is a type of endoplasmic reticulum (ER)-membrane receptor. STING is activated by a ligand binding, which leads to an enhancement of the immune-system response. Therefore, a STING ligand can be used to regulate t
Externí odkaz:
https://doaj.org/article/abba75019b0947798afa2063d7ce93a0
Autor:
Norihiko Sakai, Miki Nakamura, Kenneth E. Lipson, Taito Miyake, Yasutaka Kamikawa, Akihiro Sagara, Yasuyuki Shinozaki, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi, Shuichi Kaneko, Andrew M. Tager, Takashi Wada
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Peritoneal fibrosis (PF) is a serious complication in various clinical settings, but the mechanisms driving it remain to be fully determined. Connective tissue growth factor (CTGF) is known to regulate fibroblast activities. We therefore exa
Externí odkaz:
https://doaj.org/article/7050ef58788c4ff3a1746051cc45f7fa
Autor:
Masahiko Yamaguchi, Yoko Watanabe, Takuji Ohtani, Akiyoshi Uezumi, Norihisa Mikami, Miki Nakamura, Takahiko Sato, Masahito Ikawa, Mikio Hoshino, Kunihiro Tsuchida, Yuko Miyagoe-Suzuki, Kazutake Tsujikawa, Shin’ichi Takeda, Hiroshi Yamamoto, So-ichiro Fukada
Publikováno v:
Cell Reports, Vol 13, Iss 2, Pp 302-314 (2015)
Calcitonin receptor (Calcr) is expressed in adult muscle stem cells (muscle satellite cells [MuSCs]). To elucidate the role of Calcr, we conditionally depleted Calcr from adult MuSCs and found that impaired regeneration after muscle injury correlated
Externí odkaz:
https://doaj.org/article/5d5c7ed7ec964b9b967d8575b02f9c47
Autor:
Hiroshi Sakai, Sumiaki Fukuda, Miki Nakamura, Akiyoshi Uezumi, Yu-Taro Noguchi, Takahiko Sato, Mitsuhiro Morita, Harumoto Yamada, Kunihiro Tsuchida, Shahragim Tajbakhsh, So-Ichiro Fukada
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177516 (2017)
Myogenic stem cells are a promising avenue for the treatment of muscular disorders. Freshly isolated muscle stem cells have a remarkable engraftment ability in vivo, but their cell number is limited. Current conventional culture conditions do not all
Externí odkaz:
https://doaj.org/article/c233ac686f4343138a5066c3fc059742
Autor:
Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Masumi Abe
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 52-63 (2014)
A large number of point mutations have been identified in induced pluripotent stem cell (iPSC) genomes to date. Whether these mutations are associated with iPSC generation is an important and controversial issue. In this study, we approached this cri
Externí odkaz:
https://doaj.org/article/e670ba6b6ca64f8b8ff0b4cc80eecc63
Autor:
Masahiko Yamaguchi, Satoshi Murakami, Tomohiro Yoneda, Miki Nakamura, Lidan Zhang, Akiyoshi Uezumi, Sumiaki Fukuda, Hiroki Kokubo, Kazutake Tsujikawa, So-Ichiro Fukada
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138517 (2015)
Nrf2 is a master regulator of oxidative stresses through the induction of anti-oxidative genes. Nrf2 plays roles in maintaining murine hematopoietic stem cells and fly intestinal stem cells. The canonical Notch signaling pathway is also crucial for m
Externí odkaz:
https://doaj.org/article/c30164e8a6324939be8b5b931696bf84
Autor:
Miki Nakamura, Megumi Nishiyama
Publikováno v:
Journal of Human Environmental Studies. 20:37-42
Publikováno v:
Journal of Architecture and Planning (Transactions of AIJ). 86:2280-2291
Autor:
Kaori Imadome, Yuko Hoki, Satoshi Kamimura, Mayumi Fujita, Ryoko Araki, Misato Sunayama, Miki Nakamura, Masumi Abe, Tomo Suga
Publikováno v:
Stem Cell Reports
Summary We here demonstrate that microsatellite (MS) alterations are elevated in both mouse and human induced pluripotent stem cells (iPSCs), but importantly we have now identified a type of human iPSC in which these alterations are considerably redu