Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Miki Katuwal"'
Autor:
Karl J. Heilman, Michael S. Harper, Yaqiong Wang, Miki Katuwal, Kimberly Schmitt, Kejun Guo, Mario L. Santiago, Edward B. Stephens, Takeo Kuwata, Kalani Halemano
Publikováno v:
Immunogenetics. 67:355-370
B cell functional defects are associated with delayed neutralizing antibody development in pathogenic lentivirus infections. However, the timeframe for alterations in the antibody repertoire and somatic hypermutation (SHM) remains unclear. Here, we u
Autor:
Kejun Guo, Mario L. Santiago, Kalani Halemano, Edward B. Stephens, Miki Katuwal, Kimberly Schmitt, Yaqiong Wang
Publikováno v:
Virology. :532-544
The APOBEC3 (A3) deaminases are retrovirus restriction factors that were proposed as inhibitory components of HIV-1 gene therapy vectors. However, A3 mutational activity may induce undesired genomic damage and enable HIV-1 to evade drugs and immune r
Publikováno v:
Virology. :140-149
Previous studies have shown that apolipoprotein B mRNA editing, enzyme catalytic, polypeptide G (APOBEC3G; hA3G) and F (APOBEC3F; hA3F) proteins interact with a nonlinear binding site located at the N-terminal region of the HIV-1 Vif protein. We have