Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Miki, Senda"'
Autor:
Kamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, Christian M. Orr, Merlyn Latimer-Smith, Graeme Winter, Vinay Grama, Feng Qu, Kiran Bountra, Hok Sau Kwong, Maria Romano, Rosana I. Reis, Lutz Vogeley, Luca Vecchia, C. David Owen, Sina Wittmann, Max Renner, Miki Senda, Naohiro Matsugaki, Yoshiaki Kawano, Thomas A. Bowden, Isabel Moraes, Jonathan M. Grimes, Erika J. Mancini, Martin A. Walsh, Cristiane R. Guzzo, Raymond J. Owens, E. Yvonne Jones, David G. Brown, Dave I. Stuart, Konstantinos Beis, Armin Wagner
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Despite recent advances in cryo-electron microscopy and artificial intelligence-based model predictions, a significant fraction of structure determinations by macromolecular crystallography still requires experimental phasing, usually by mea
Externí odkaz:
https://doaj.org/article/8684a241320c432f8b25757e0cf6d695
Autor:
Miho Watanabe-Takahashi, Miki Senda, Ryunosuke Yoshino, Masahiro Hibino, Shinichiro Hama, Tohru Terada, Kentaro Shimizu, Toshiya Senda, Kiyotaka Nishikawa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Shiga toxin (Stx), a major virulence factor of enterohemorrhagic Escherichia coli (EHEC), can cause fatal systemic complications. Recently, we identified a potent inhibitory peptide that binds to the catalytic A-subunit of Stx. Here, using b
Externí odkaz:
https://doaj.org/article/c2782278432e409e8b97ae9a82df8762
Autor:
Kazue Inaba, Kana Ebihara, Miki Senda, Ryunosuke Yoshino, Chisako Sakuma, Kotaro Koiwai, Daisuke Takaya, Chiduru Watanabe, Akira Watanabe, Yusuke Kawashima, Kaori Fukuzawa, Riyo Imamura, Hirotatsu Kojima, Takayoshi Okabe, Nozomi Uemura, Shinji Kasai, Hirotaka Kanuka, Takashi Nishimura, Kodai Watanabe, Hideshi Inoue, Yuuta Fujikawa, Teruki Honma, Takatsugu Hirokawa, Toshiya Senda, Ryusuke Niwa
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Mosquito control is a crucial global issue for protecting the human community from mosquito-borne diseases. There is an urgent need for the development of selective and safe reagents for mosquito control. Flavonoids, a group of ch
Externí odkaz:
https://doaj.org/article/b49433e4465946a08dd1ecf88c040e05
Autor:
Takahiro Mori, Takuto Kumano, Haibing He, Satomi Watanabe, Miki Senda, Toshio Moriya, Naruhiko Adachi, Sanae Hori, Yuzu Terashita, Masato Kawasaki, Yoshiteru Hashimoto, Takayoshi Awakawa, Toshiya Senda, Ikuro Abe, Michihiko Kobayashi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In C-glycosides the sugar moiety is linked through a carbon-carbon bond to the non-sugar moiety, which can be cleaved by intestinal microbes. Here, the authors use bioinformatics analysis to identify C-glycoside deglycosidase enzymes in intestinal an
Externí odkaz:
https://doaj.org/article/be2834e7f7604e8f81be75ba24bda5b8
Autor:
Yoshihisa Hirakawa, Miki Senda, Kodai Fukuda, Hong Yang Yu, Masaki Ishida, Masafumi Taira, Kazushi Kinbara, Toshiya Senda
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Carbonic anhydrases (CAs) are universal metalloenzymes that catalyze the reversible conversion of carbon dioxide (CO2) and bicarbonate (HCO3 -). They are involved in various biological processes, including pH control, respiration,
Externí odkaz:
https://doaj.org/article/660df3040c91440e873066b9fdf49a18
Autor:
Miho Watanabe-Takahashi, Masakazu Tamada, Miki Senda, Masahiro Hibino, Eiko Shimizu, Akiko Okuta, Atsuo Miyazawa, Toshiya Senda, Kiyotaka Nishikawa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Watanabe-Takahashi, Tamada, Senda et al. identify a tetravalent peptide that inhibits Shiga toxin (Stx), a major virulence factor of enterohemorrhagic Escherichia coli, by targeting its receptor-binding. On the other hand, a monomeric peptide contain
Externí odkaz:
https://doaj.org/article/bbdaed596a724d62b77588f4c9ef5bc4
Autor:
Yu Nakashima, Takahiro Mori, Hitomi Nakamura, Takayoshi Awakawa, Shotaro Hoshino, Miki Senda, Toshiya Senda, Ikuro Abe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Non-heme iron and α-ketoglutarate (αKG) oxygenases play a major role in fungal meroterpenoid biosynthesis, but their mechanism remains elusive. Here the authors present crystal structures of two oxygenases, AusE and PrhA, which provide insights int
Externí odkaz:
https://doaj.org/article/a9d82d60fc91499ea620314cccccd36f
Autor:
Takeru Hayashi, Miki Senda, Nobuhiro Suzuki, Hiroko Nishikawa, Chi Ben, Chao Tang, Lisa Nagase, Kaori Inoue, Toshiya Senda, Masanori Hatakeyama
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2876-2890 (2017)
Helicobacter pylori East Asian CagA is more closely associated with gastric cancer than Western CagA. Here we show that, upon tyrosine phosphorylation, the East Asian CagA-specific EPIYA-D segment binds to the N-SH2 domain of pro-oncogenic SHP2 phosp
Externí odkaz:
https://doaj.org/article/0c000b922a6440fd860b571bbe0db464
Autor:
Koh Takeuchi, Miki Senda, Yoshiki Ikeda, Koji Okuwaki, Kaori Fukuzawa, So Nakagawa, Mika Sasaki, Atsuo T. Sasaki, Toshiya Senda
Publikováno v:
The FEBS Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2fd86c53309c0b7a73ec42f1b4240a
https://doi.org/10.1111/febs.16763
https://doi.org/10.1111/febs.16763
Autor:
Jun Kobayashi, Minetaro Arita, Shota Sakai, Hirotatsu Kojima, Miki Senda, Toshiya Senda, Kentaro Hanada, Ryuichi Kato
Publikováno v:
ACS Infectious Diseases. 8:1161-1170
Oxysterol-binding protein (OSBP), which transports cholesterol and phosphatidylinositol 4-monophosphate (PtdIns[4]P) between different organelles, serves as a conserved host factor for the replication of various viruses, and OSBP inhibitors exhibit a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b57358b944e88088c55ba7e05b6ad41
https://doi.org/10.1021/acsinfecdis.2c00108
https://doi.org/10.1021/acsinfecdis.2c00108