Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Miki, Nakajima"'
Autor:
Madhu Biyani, Kirti Sharma, Maeda Shoei, Hinako Akashi, Masataka Nakano, Miki Nakajima, Manish Biyani
Publikováno v:
Biosensors and Bioelectronics: X, Vol 19, Iss , Pp 100491- (2024)
Human adenosine deaminase acting on RNA1 (ADAR1) is an adenosine-to-inosine (A-to-I) RNA-editing enzyme involved in various types of cancer progression. ADAR1 has emerged as a novel prognostic biomarker for cancer. This study describes the applicatio
Externí odkaz:
https://doaj.org/article/f24056a24f634aec87ec752245b259ae
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 6, p 145 (2024)
It is generally accepted that the Moon accreted from the disk formed by an impact between the proto-Earth and impactor, but its details are highly debated. Some models suggest that a Mars-sized impactor formed a silicate melt-rich (vapor-poor) disk a
Externí odkaz:
https://doaj.org/article/475f4e692b794336a03bedad47fa542c
Publikováno v:
The Planetary Science Journal, Vol 5, Iss 1, p 9 (2024)
The amount of vapor in the impact-generated protolunar disk carries implications for the dynamics, devolatilization, and moderately volatile element isotope fractionation during lunar formation. The equation of state (EoS) used in simulations of the
Externí odkaz:
https://doaj.org/article/70988f8a08aa4ce2a5c431e0ee5d4260
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
This study finds that the Moon accreted from an initially liquid-rich silicate disk and that rocky and icy exoplanets whose radii are smaller than 1.6 Earth radii are ideal candidates for hosting large exomoons.
Externí odkaz:
https://doaj.org/article/a6920d2cc13143c2a83f5bb99368c7af
Autor:
Koki Katayama, Shimon Nakashima, Hiroo Ishida, Yutaro Kubota, Masataka Nakano, Tatsuki Fukami, Yasutsuna Sasaki, Ken-ichi Fujita, Miki Nakajima
Publikováno v:
Non-coding RNA Research, Vol 6, Iss 3, Pp 123-129 (2021)
Single nucleotide polymorphisms in genes encoding microRNAs (miRNA-SNPs) may affect the maturation steps of miRNAs or target mRNA recognition, leading to changes in the expression of target mRNAs to cause gain- or loss-of-function changes. Several mi
Externí odkaz:
https://doaj.org/article/19faf567fce240339e0b270504a3c810
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1671-1680
Autor:
Francesca Cirillo, Rosamaria Lappano, Leonardo Bruno, Bruno Rizzuti, Fedora Grande, Rita Guzzi, Sara Briguori, Anna Maria Miglietta, Miki Nakajima, Maria Teresa Di Martino, Marcello Maggiolini
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Abstract Background The chemical carcinogen 3-methylcholanthrene (3MC) binds to the aryl hydrocarbon receptor (AHR) that regulates the expression of cytochrome P450 (CYP) enzymes as CYP1B1, which is involved in the oncogenic activation of environment
Externí odkaz:
https://doaj.org/article/104fa2be1b3d48febf1f6a8240c87056
Autor:
Shimon Nakashima, Rei Sato, Tatsuki Fukami, Takashi Kudo, Shiori Hashiba, Gaku Morinaga, Masataka Nakano, Eva Ludwig-Schwellinger, Akiko Matsui, Naoki Ishiguro, Thomas Ebner, Miki Nakajima
Publikováno v:
Drug Metabolism and Disposition. 51:733-742
Autor:
Masaki Ri, Shimon Nakashima, Miki Nakajima, Shinsuke Iida, Dai Maruyama, Satoshi Osaga, Kensei Tobinai, Noriko Fukuhara, Kana Miyazaki, Norifumi Tsukamoto, Hideki Tsujimura, Makoto Yoshimitsu, Kenichi Miyamoto, Kunihiro Tsukasaki, Hirokazu Nagai
Publikováno v:
Blood. 140:12647-12649
Publikováno v:
Drug Metabolism and Disposition. 50:725-733
Sulindac is a nonsteroidal anti-inflammatory prodrug that is converted to its pharmacologically active metabolite, sulindac sulfide, via a reduction reaction. It is widely accepted that the gut microbiota is responsible for sulindac activation; howev