Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Miki, Inoue"'
Autor:
Miki Inoue, Takashi Baba, Fumiya Takahashi, Miho Terao, Shogo Yanai, Yuichi Shima, Daisuke Saito, Kei Sugihara, Takashi Miura, Shuji Takada, Mikita Suyama, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Investigation of fetal Leydig progenitors shows that thymosin β10 (Tmsb10) suppresses the RAS/ERK pathway, inducing progenitor differentiation into fetal Leydig cells.
Externí odkaz:
https://doaj.org/article/3bdd9960171d464396c4238431385530
Autor:
Antonius Christianto, Takashi Baba, Fumiya Takahashi, Kai Inui, Miki Inoue, Mikita Suyama, Yusuke Ono, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Baba et al. analyzed the transcriptomes from quadriceps type IIB fibers of untreated, gonadectomized, and sex steroid-treated mice of both sexes and identified Pfkfb3 and Pdk4 as differentially regulated genes between males and diestrus females. The
Externí odkaz:
https://doaj.org/article/44988098e0d94e429ef8c3e6cc06eaf5
Autor:
Shogo Yanai, Takashi Baba, Kai Inui, Kanako Miyabayashi, Soyun Han, Miki Inoue, Fumiya Takahashi, Yoshiakira Kanai, Yasuyuki Ohkawa, Man Ho Choi, Ken-ichirou Morohashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The SRY gene induces testis development even in XX individuals. However, XX/Sry testes fail to produce mature sperm, due to the absence of Y chromosome carrying genes essential for spermatogenesis. XX/Sry Sertoli cells show abnormalities in
Externí odkaz:
https://doaj.org/article/b7fc0ba3de484d65be555e4d60d3bc8e
Publikováno v:
Endocrinology and Metabolism, Vol 35, Iss 4, Pp 756-764 (2020)
The agenesis of the gonads and adrenal gland in revealed by knockout mouse studies strongly suggested a crucial role for Nr5a1 (SF-1 or Ad4BP) in organ development. In relation to these striking phenotypes, NR5A1/Nr5a1 has the potential to reprogram
Externí odkaz:
https://doaj.org/article/f101b7d88f774c5abe6d050e64ffcd92
Autor:
Sachiko Omotani, Toshihiko Ishizaka, Miki Inoue, Koji Nishida, Yukako Yasui, Yasutoshi Hatsuda, Junji Mukai, Michiaki Myotoku
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 6, Iss 1, Pp 1-5 (2020)
Abstract Background Interferon and ribavirin have been used as therapeutic agents for chronic hepatitis C infection or C-compensated cirrhosis in the conventional treatment. Hepatitis C virus (HCV) -specific direct-acting antiviral agents that direct
Externí odkaz:
https://doaj.org/article/5901cd5c42054e38b6782f68989f63d4
Autor:
Miki Inoue, Takashi Baba, Fumiya Takahashi, Miho Terao, Shogo Yanai, Yuichi Shima, Daisuke Saito, Kei Sugihara, Takashi Miura, Shuji Takada, Mikita Suyama, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Leydig cells in fetal testes play crucial roles in masculinizing fetuses through androgen production. Gene knockout studies have revealed that growth factors are implicated in fetal Leydig cell (FLC) differentiation, but little is known about the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433a243653074bc2a23a8bf8451ee818
https://doi.org/10.21203/rs.3.rs-1357916/v1
https://doi.org/10.21203/rs.3.rs-1357916/v1
Publikováno v:
Plant molecular biology. 110(4-5)
Alterations in DNA methylation levels of ROS, GA and ABA related gene promoters cause transcriptional changes upon imbibition to induce seed germination in barley seeds exposed to heat stress during grain filling. Environmental changes, especially ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a411e76c4784fa41008249de7fd1a3ae
https://pubmed.ncbi.nlm.nih.gov/35581415
https://pubmed.ncbi.nlm.nih.gov/35581415
Autor:
Ken Ichirou Morohashi, Takashi Baba, Yusuke Ono, Kai Inui, Mikita Suyama, Fumiya Takahashi, Yasuyuki Ohkawa, Miki Inoue, Antonius Christianto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
Skeletal muscles display sexually dimorphic features. Biochemically, glycolysis and fatty acid β-oxidation occur preferentially in the muscles of males and females, respectively. However, the mechanisms of the selective utilization of these fuels re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006415c0888773ad357dbf81eef223a6
https://doi.org/10.1038/s42003-021-02790-y
https://doi.org/10.1038/s42003-021-02790-y
Autor:
Mika Ikegaya, Go Nagamatsu, Haruka Yabukami, Takashi Yoshino, Ken Ichirou Morohashi, Miki Inoue, Ryuichi Nishinakamura, Takuya Imamura, Kinichi Nakashima, Yuichi Shima, Haruka Kita, Katsuhiko Hayashi, Makoto Tachibana, Takahiro Suzuki, Mami Kishima
Publikováno v:
Science. 373
Reconstituting the ovarian follicle Recent advances have enabled the generation of oocytes from pluripotent stem cells in vitro. However, these cells require a somatic environment to develop fully as reproductive cells. Yoshino et al. applied what is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5038aafee42e2aa70096bb563406f31
https://doi.org/10.1126/science.abe0237
https://doi.org/10.1126/science.abe0237
Autor:
Soyun Han, Yasuyuki Ohkawa, Fumiya Takahashi, Miki Inoue, Ken Ichirou Morohashi, Man Ho Choi, Kanako Miyabayashi, Takashi Baba, Kai Inui, Shogo Yanai, Yoshiakira Kanai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
The SRY gene induces testis development even in XX individuals. However, XX/Sry testes fail to produce mature sperm, due to the absence of Y chromosome carrying genes essential for spermatogenesis. XX/Sry Sertoli cells show abnormalities in the produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd200f5f64b06fa2e305c55b78b6780
http://europepmc.org/articles/PMC7804417
http://europepmc.org/articles/PMC7804417