Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Miki, Furusho"'
Publikováno v:
Glia. 69:2429-2446
Multiple signals are involved in the regulation of developmental myelination by Schwann cells and in the maintenance of a normal myelin homeostasis throughout adult life, preserving the integrity of the axons in the PNS. Recent studies suggest that M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9cf9d64b5d849b74c3a899c252489d
https://doi.org/10.1002/glia.24049
https://doi.org/10.1002/glia.24049
Publikováno v:
Glia
FGF signaling is important for numerous cellular processes and produces diverse cellular responses. Our recent studies using mice conditionally lacking FGF-Receptor-1 (Fgfr1) or Fgfr2 during different stages of myelinogenesis revealed that Fgfr signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22af138a6089389249f10d5d667a1c0
https://pubmed.ncbi.nlm.nih.gov/31670856
https://pubmed.ncbi.nlm.nih.gov/31670856
Autor:
Miki Furusho, Joshay Ford, Jessica W. Tutolo, Kristine H. Le, Rashmi Bansal, Michael J. Maggipinto, Elisa Barbarese, John W Wizeman
Publikováno v:
Glia. 65:489-501
The tumor overexpressed gene (TOG) protein is present in RNA granules that transport myelin basic protein (MBP) mRNA in oligodendrocyte processes to the myelin compartment. Its role was investigated by conditionally knocking it out (KO) in myelinatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85493c7dcc24db7200a76a4cc65d5eec
https://doi.org/10.1002/glia.23106
https://doi.org/10.1002/glia.23106
Publikováno v:
Glia. 67(7)
Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27981570502bd9555fd6b0f1218ed6ef
https://pubmed.ncbi.nlm.nih.gov/30761608
https://pubmed.ncbi.nlm.nih.gov/30761608
Publikováno v:
Glia. 63:1714-1728
Remyelination is a potent regenerative process in demyelinating diseases, such as multiple sclerosis, the effective therapeutic promotion of which will fill an unmet clinical need. The development of proregenerative therapies requires the identificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa26372aed8b2a9e1f735f4ecd3302d1
https://doi.org/10.1002/glia.22838
https://doi.org/10.1002/glia.22838
FGF signaling has emerged as a significant “late-stage” regulator of myelin thickness in the CNS, independent of oligodendrocyte differentiation. Therefore, it is critically important to identify the specific FGF receptor type and its downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec22c145e50088b5f03946852aba3632
https://europepmc.org/articles/PMC5354334/
https://europepmc.org/articles/PMC5354334/
Autor:
Michael J, Maggipinto, Joshay, Ford, Kristine H, Le, Jessica W, Tutolo, Miki, Furusho, John W, Wizeman, Rashmi, Bansal, Elisa, Barbarese
Publikováno v:
Glia. 65(3)
The tumor overexpressed gene (TOG) protein is present in RNA granules that transport myelin basic protein (MBP) mRNA in oligodendrocyte processes to the myelin compartment. Its role was investigated by conditionally knocking it out (KO) in myelinatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d636a28adf6eb6c61f9b3e6d935a800
https://pubmed.ncbi.nlm.nih.gov/28063167
https://pubmed.ncbi.nlm.nih.gov/28063167
Publikováno v:
The Journal of Neuroscience. 31:5055-5066
Fibroblast growth factors (FGFs) comprise a family of developmental regulators implicated in a wide variety of neurological functions. FGF receptors 1, 2, and 3 (Fgfrs) are expressed in the embryonic forebrain, including regions overlapping with vent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989482dd3bd264e9ba1e4ad352d122d2
https://doi.org/10.1523/jneurosci.4800-10.2011
https://doi.org/10.1523/jneurosci.4800-10.2011
Publikováno v:
The Journal of Neuroscience. 29:1608-1614
Axon–glial interactions are critical for normal functioning of peripheral nerves, and their disruption leads to peripheral neuropathies. Fibroblast growth factors (FGFs) are key players in peripheral nerve regeneration after injury. We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d7f157e7540af5d6a6154ef325a8f9
https://doi.org/10.1523/jneurosci.5615-08.2009
https://doi.org/10.1523/jneurosci.5615-08.2009
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(24)
Myelin growth is a tightly regulated process driven by multiple signals. ERK1/2-MAPK signaling is an important regulator of myelin thickness. Because, in demyelinating diseases, the myelin formed during remyelination fails to achieve normal thickness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170d503ce498b0cd647dd37b1182fd5b
https://pubmed.ncbi.nlm.nih.gov/27307235
https://pubmed.ncbi.nlm.nih.gov/27307235