Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mikhail Yu, Vyssokikh"'
Autor:
Ekaterina A. Gorshkova, Ekaterina O. Gubernatorova, Ekaterina M. Dvorianinova, Taisiya R. Yurakova, Maria V. Marey, Olga A. Averina, Susanne Holtze, Thomas B. Hildebrandt, Alexey A. Dmitriev, Marina S. Drutskaya, Mikhail Yu. Vyssokikh, Sergei A. Nedospasov
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The naked mole-rat (NMR) is a unique long-lived rodent which is highly resistant to age-associated disorders and cancer. The immune system of NMR possesses a distinct cellular composition with the prevalence of myeloid cells. Thus, the detailed pheno
Externí odkaz:
https://doaj.org/article/da98d8b4584e46329cf20f783b52b147
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Boris V. Chernyak, Armen Y. Mulkidjanian, Maxim V. Skulachev, Gregory A. Shilovsky, Konstantin G. Lyamzaev, Vitaliy B. Borisov, Fedor F. Severin, Victor A. Sadovnichii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12540 (2023)
Cellular respiration is associated with at least six distinct but intertwined biological functions. (1) biosynthesis of ATP from ADP and inorganic phosphate, (2) consumption of respiratory substrates, (3) support of membrane transport, (4) conversion
Externí odkaz:
https://doaj.org/article/e0c1fa324f424ca8a9e70842da931f30
Autor:
Alisa A. Panteleeva, Thomas B. Hildebrandt, O. A. Averina, Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Roman A. Zinovkin, Nicolas Fasel, Fedor F. Severin, Konstantin G. Lyamzaev, M. V. Marey, Susanne Holtze, Maxim V. Skulachev
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117(12):6491-6501
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6491-6501
Proceedings of the National Academy of Sciences of the United States of America, 117(12):6491-6501
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6491-6501
Significance The mitochondria, organelles that produce the largest amounts of ATP and reactive oxygen species (mROS) in living cells, are equipped with a universal mechanism that can completely prevent mROS production. This mechanism consists of mild
Autor:
Hynek Burda, Delphine del Marmol, E. A. Gorshkova, Yoshiyuki Henning, Sabine Begall, Satomi Miwa, Thomas B. Hildebrandt, Andreas Hoeflich, Mikhail Yu. Vyssokikh, Thomas von Zglinicki, O. A. Averina, Yury Shebzukhov, Julia Brenmoehl, Tobias Jung, Susanne Holtze, Dania Hamo, Radim Šumbera, Philip Dammann, Annika Höhn, Stan Braude, Arne Sahm
Publikováno v:
Braude, S, Holtze, S, Begall, S, Brenmoehl, J, Burda, H, Dammann, P, del Marmol, D, Gorshkova, E, Henning, Y, Hoeflich, A, Höhn, A, Jung, T, Hamo, D, Sahm, A, Shebzukhov, Y, Šumbera, R, Miwa, S, Vyssokikh, M Y, von Zglinicki, T, Averina, O & Hildebrandt, T B 2021, ' Surprisingly long survival of premature conclusions about naked mole-rat biology ', Biological Reviews, vol. 96, no. 2, pp. 376-393 . https://doi.org/10.1111/brv.12660
Biological reviews, 96(2):376-393
Biological reviews, 96(2):376-393
Naked mole-rats express many unusual traits for such a small rodent. Their morphology, social behaviour, physiology, and ageing have been well studied over the past half-century. Many early findings and speculations about this subterranean species pe
Autor:
Perinatology, Roman A. Zinovkin, Alisa A. Panteleeva, Thomas B. Hildebrandt, Nicolas Fasel, O. A. Averina, Fedor F. Severin, Susanne Holtze, Maxim V. Skulachev, Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Konstantin G. Lyamzaev, M. V. Marey
Publikováno v:
Proceedings of the 3rd International Conference in celebration of the 85th birthday of professor V.P. Skulachev. Abstract Book.
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Stan Braude, Thomas B. Hildebrandt, Susanne Holtze
Publikováno v:
Proceedings of the 3rd International Conference in celebration of the 85th birthday of professor V.P. Skulachev. Abstract Book.
Autor:
V.V. Ashapkin, Alexander V. Markov, Olga Yamskova, E.V. Sorokina, S. I. Shram, T S Putyatina, Vassily A. Lyubetsky, Mikhail Yu. Vyssokikh, G. A. Shilovsky
Publikováno v:
Biochemistry. Biokhimiia. 84(12)
Age-related dysfunctions are accompanied by impairments in the mitochondrial morphology, activity of signaling pathway, and protein interactions. Cardiolipin is one of the most important phospholipids that maintains the curvature of the cristae and f
Autor:
Lora E. Bakeeva, Alexander V. Markov, Maxim V. Skulachev, Thomas B. Hildebrandt, Vladimir P. Skulachev, Viktor A. Sadovnichii, Susanne Holtze, Mikhail Yu. Vyssokikh
Publikováno v:
Physiological Reviews. 97:699-720
It has been suggested that highly social mammals, such as naked mole rats and humans, are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot operate as a mechanism facilitating natural selection because the pressure
Autor:
Vladimir V. Aleoshin, Yuri V. Panchin, Olga Zanegina, Maria S. Muntyan, Alexander Y Panchin, Dmitry A. Knorre, Maria D. Logacheva, Mikhail Yu. Vyssokikh, Sergei E. Spiridonov, Mikhail A. Nikitin, Boris D. Efeykin, Kirill V. Mikhailov, Olga V. Popova, Aleksey A. Penin
Publikováno v:
Nucleic Acids Research
Inverted repeats are common DNA elements, but they rarely overlap with protein-coding sequences due to the ensuing conflict with the structure and function of the encoded protein. We discovered numerous perfect inverted repeats of considerable length
Autor:
Irina G, Shabalina, Mikhail Yu, Vyssokikh, Natalia, Gibanova, Robert I, Csikasz, Daniel, Edgar, Anne, Hallden-Waldemarson, Zinaida, Rozhdestvenskaya, Lora E, Bakeeva, Valeria B, Vays, Antonina V, Pustovidko, Maxim V, Skulachev, Barbara, Cannon, Vladimir P, Skulachev, Jan, Nedergaard
Publikováno v:
Aging (Albany NY)
MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering