Výsledky vyhledávání - "Mikhail Y. Vysokikh"

Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae

Autor: Gemma C. Atkinson, Aksel Soosaar, Tanel Tenson, Stoyan Tankov, Mikhail Y. Vysokikh, Valentina Lakunina, Ekaterina A. Smirnova, Anton Kuzmenko, Vasili Hauryliuk, Piotr Kamenski

Publikováno v: Nucleic Acids Research

Mitochondrial translation is essentially bacteria-like, reflecting the bacterial endosymbiotic ancestry of the eukaryotic organelle. However, unlike the translation system of its bacterial ancestors, mitochondrial translation is limited to just a few

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444aad23d7943b0b3543c4038b3933d1
https://doi.org/10.1093/nar/gks272

Zobrazit plný text záznamu

Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria

Autor: Abdeldjalil Boucheham, Anne-Marie Mager-Heckel, Tom Schirtz, Olga Karicheva, Robert P. Martin, Nina Entelis, Olga Kolesnikova, Mikhail Y. Vysokikh, Igor A. Krasheninnikov, Anne Lombès, Ivan Tarassov

Publikováno v: Nucleic Acids Research

Mutations in human mitochondrial DNA are often associated with incurable human neuromuscular diseases. Among these mutations, an important number have been identified in tRNA genes, including 29 in the gene MT-TL1 coding for the tRNA(Leu(UUR)). The m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6f8eab79c213f15268dc8dc8c2fb5e
http://europepmc.org/articles/PMC3185436

Zobrazit plný text záznamu

Modeling of Antigenomic Therapy of Mitochondrial Diseases by Mitochondrially Addressed RNA Targeting a Pathogenic Point Mutation in Mitochondrial DNA*

Autor: Anne-Marie Heckel, Ilya S. Dovydenko, Agnès Rötig, Yann Tonin, Ivan Tarassov, Mikhail Y. Vysokikh, Arnold Munnich, Alya G. Venyaminova, Mariya I. Meschaninova, Nina Entelis

Defects in mitochondrial genome can cause a wide range of clinical disorders, mainly neuromuscular diseases. Presently, no efficient therapeutic treatment has been developed against this class of pathologies. Because most of deleterious mitochondrial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063235b5b4b745299c5d5f08f64be635
https://europepmc.org/articles/PMC4036341/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání