High-Pressure Monosulfide Solid Solution FexNi1−xS Phases: X-Ray Diffraction Analysis and Raman Spectroscopy

Autor: Anna V. Spivak, Ninel Yu. Sharapova, Tatiana V. Setkova, Andrey V. Bobrov, Vitaliy I. Korepanov, Anastasia V. Iskrina, Egor S. Zakharchenko, Mikhail V. Voronin, Natalia A. Drozhzhina

Publikováno v: Crystals, Vol 14, Iss 11, p 967 (2024)

High-pressure high-temperature (HPHT) crystalline monosulfide solid solution (Mss) phases (FexNi1−xS, x = 0.90, 0.75, 0.50, 0.25), troilite (FeS I), and α-NiS of the Fe-Ni-S system were synthesized at 7 GPa and 900–1550 °C. The structural param

Externí odkaz: https://doaj.org/article/2d20ef57a03f4e5db7f85fcff6e7fdc0

Pharmacological Analysis of GABAA Receptor and Sigma1R Chaperone Interaction: Research Report I―Investigation of the Anxiolytic, Anticonvulsant and Hypnotic Effects of Allosteric GABAA Receptors’ Ligands

Autor: Seredenin, Mikhail V. Voronin, Stanislav V. Shangin, Svetlana A. Litvinova, Elena V. Abramova, Rustam D. Kurbanov, Inna V. Rybina, Yulia V. Vakhitova, Sergei B.

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9580

Two groups of facts have been established in previous drug development studies of the non-benzodiazepine anxiolytic fabomotizole. First, fabomotizole prevents stress-induced decrease in binding ability of the GABAA receptor’s benzodiazepine site. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::4d034d245adf165ee5b0084064d2115f

Neuroprotective Properties of Quinone Reductase 2 Inhibitor M-11, a 2-Mercaptobenzimidazole Derivative

Autor: Mikhail V. Voronin, Ilya A. Kadnikov, Liana F. Zainullina, Ilya O. Logvinov, Ekaterina R. Verbovaya, Tatyana A. Antipova, Yulia V. Vakhitova, Sergei B. Seredenin

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13061, p 13061 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13061
International Journal of Molecular Sciences

The ability of NQO2 to increase the production of free radicals under enhanced generation of quinone derivatives of catecholamines is considered to be a component of neurodegenerative disease pathogenesis. The present study aimed to investigate the n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e78edbc8e73beccc109de7c97492e4
https://www.mdpi.com/1422-0067/22/23/13061

Multiple mechanisms underlying the cytoprotective effect of afobazole

Autor: Sergey B. Seredenin, Mikhail V. Voronin, Ilya A. Kadnikov

Publikováno v: Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO1-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c223c0ab73d6cd16565d14ebb2005d6d
https://doi.org/10.1254/jpssuppl.wcp2018.0_po1-6-6

Chaperone Sigma1R mediates the neuroprotective action of afobazole in the 6-OHDA model of Parkinson’s disease

Autor: Dmitry N. Voronkov, Ilya A. Kadnikov, Mikhail V. Voronin, Sergey B. Seredenin

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

Parkinson’s disease (PD) is a progressive neurodegenerative disease with limited treatment options. Therefore, the identification of therapeutic targets is urgently needed. Previous studies have shown that the ligand activation of the sigma-1 chape

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18facf8b5baf9d6f2884fc76c7706962
https://doi.org/10.1038/s41598-019-53413-w