Výsledky vyhledávání - "Mikhail V. Dorogov"

Phosphorescent Platinum(II) Complexes Featuring Chelated Acetoxime Pyrazoles: Synthetic, Structural, and Photophysical Study

Autor: Mikhail V. Dorogov, Alexander S. Novikov, Yuri Novozhilov, Oksana Ronzhina, Dmitrii S. Bolotin, Ilya E. Kolesnikov, Vitaliy V. Suslonov, Vadim Yu. Kukushkin, Mikhail Krasavin

Publikováno v: ChemistrySelect. 1:456-461

Treatment of cis-[PtCl2(Me2SO)2] with the pyrazole acetoximes p-RC6H4{CN(H)NCCH}CH2C(Me)=NOH (R=OMe, H, F, Cl, CN, NO2), prepared by a cascade reaction from the vinyl isoxazoles p-RC6H4C(H)=C(H){CONCC(NO2)}Me, leads to the complexes [PtCl2(Ar{CN(H)NC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c60d456d8ca79d78249a6d9e8002605
https://doi.org/10.1002/slct.201600130

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Atom-economical construction of tetracyclic [1,4]oxazepines involving intramolecular arylation of a 2-imidazoline moiety

Autor: Mikhail V. Dorogov, Kseniya Karamysheva, Mikhail Krasavin, Elena Reutskaya, Alexander Sapegin

Publikováno v: Tetrahedron Letters. 56:5632-5636

Novel [1,4]oxazepines containing a fused imidazoline moiety were synthesized from 2-hydroxyphenyl imidazolines and bis-electrophilic aromatic substrates in a reaction involving sequential nucleophilic aromatic substitution steps and a Smiles rearrang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b6ca5ee548c7c0f296a1442adf86282
https://doi.org/10.1016/j.tetlet.2015.08.062

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Facile Pd-catalyzed amination of imidazolin-1-yl chloroazines under microwave irradiation: toward a new kinase-inhibitory chemotype

Autor: Mikhail V. Dorogov, Anton Shetnev, Prashant Mujumdar, Pakornwit Sarnpitak, Mikhail Krasavin

Publikováno v: Tetrahedron Letters. 56:2827-2831

The imidazolin-1-yl azine moiety, constructed using a recently developed Buchwald–Hartwig-type arylation methodology, displays excellent chemical stability under subsequent microwave-assisted Pd-catalyzed amination with a range of N-nucleophiles. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41e33bc7dce42f93f954b54831af3369
https://doi.org/10.1016/j.tetlet.2015.04.059

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Efficient Use of 1,2-Dihaloazine Synthons in Transition-Metal-Free Preparation of Diverse Heterocycle-Fused 1,4-Oxazepines

Autor: Mikhail V. Dorogov, Alexey V. Smirnov, Mikhail Krasavin, Alexander Sapegin, Stanislav Kalinin

Publikováno v: European Journal of Organic Chemistry. 2015:1333-1340

A previously reported condensation reaction of ambiphilic 2-(1H-pyrazol-5-yl)phenols with various o-chloro-substituted nitroaromatic synthons to provide medicinally important tetracyclic pyrazolo[1,5-d][1,4]oxazepines was extended to more readily ava

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e48b5630a74a9b64b423d143c1bbedf8
https://doi.org/10.1002/ejoc.201403397

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A convenient preparation of diversely substituted fused 2-amino- and 2-alkylthionicotinonitriles under microwave irradiation

Autor: Mikhail Krasavin, Alexander Sapegin, Mikhail V. Dorogov

Publikováno v: Tetrahedron Letters. 56:56-60

We describe a convenient and operationally simple protocol to prepare nicotinonitriles fused to either a cycloalkane or a saturated heterocycle, containing diverse substituents at position 2 of the nicotinonitrile core, under microwave irradiation. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14731a825e86a3923f09fe63291b88ba
https://doi.org/10.1016/j.tetlet.2014.09.067

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An expeditious and atom-economic synthesis of lead-like, medicinally important 4,5-dihydropyrazolo[1,5-a]pyrazin-6-ones

Autor: Mikhail V. Dorogov, Prashant Mujumdar, Alexander Sapegin, Mikhail Krasavin

Publikováno v: Tetrahedron Letters. 55:5732-5735

We have developed an expeditious and atom-economic synthesis of lead-like, privileged 4,5-dihydropyrazolo[1,5-a]pyrazin-6-ones, which is based on Sonogashira coupling and a two-step condensation with hydrazine hydrate leading to two ring-forming even

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbad25d98d02173024b7f2a0a1aabb4f
https://doi.org/10.1016/j.tetlet.2014.06.104

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Atom-Economical Construction of a Rare 6,7-Dihydropyrido[3′,2′:4,5]imidazo[1,2-d][1,4]benzodiazepine Scaffold

Autor: Mikhail V. Dorogov, Prashant Mujumdar, Mikhail Krasavin, Mikhail Korsakov

Publikováno v: Synlett. 25:2323-2326

We have developed a route towards novel 6,7-dihydropyrido[3′,2′:4,5]imidazo[1,2-d][1,4]benzodiazepines, in five straightforward steps from commercially available 2-bromobenzaldehydes and 3-(2-aminoethyl)imidazo[4,5-b]pyridines we have described p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16ece652822c88f68ded567e3bdf6d58
https://doi.org/10.1055/s-0034-1378558

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New tetracyclic 1,4-oxazepines constructed via practically simple tandem condensation strategy from readily available synthons

Autor: Stanislav Kalinin, Alexey V. Smirnov, Mikhail V. Dorogov, Alexander Sapegin, Mikhail Krasavin

Publikováno v: Tetrahedron. 70:1077-1083

A streamlined synthetic methodology towards novel tetracyclic 1,4-oxazepines from readily available precursors is described. The compounds, designed as more soluble version of the earlier described, poorly soluble dibenzo[b,f][1,4]oxazepines, were ob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5c92446598b82d45ba7af75ce4d3ffb
https://doi.org/10.1016/j.tet.2013.12.026

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