Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Mikhail V, Pletnikov"'
Autor:
Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange P. Brown, Mikhail V. Pletnikov, Atsushi Kamiya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 (Cnr1) is expressed not only in neurons and astrocytes, but also in microglia, which shape synaptic connections durin
Externí odkaz:
https://doaj.org/article/26cf4f08ed724225b7ffc7f3a89a4583
Autor:
Kateryna Murlanova, Yan Jouroukhin, Ksenia Novototskaya-Vlasova, Shovgi Huseynov, Olga Pletnikova, Michael J. Morales, Yun Guan, Atsushi Kamiya, Dwight E. Bergles, David M. Dietz, Mikhail V. Pletnikov
Publikováno v:
Cells, Vol 12, Iss 10, p 1412 (2023)
Astrocytes express mu/µ opioid receptors, but the function of these receptors remains poorly understood. We evaluated the effects of astrocyte-restricted knockout of µ opioid receptors on reward- and aversion-associated behaviors in mice chronicall
Externí odkaz:
https://doaj.org/article/26d7ea31e0aa4d55a6b9ddc5ba3e91bc
Autor:
Rebeca Mejias, Juan J. Rodriguez-Gotor, Minae Niwa, Irina N. Krasnova, Abby Adamczyk, Mei Han, Gareth M. Thomas, Zheng-Xiong Xi, Richard L. Huganir, Mikhail V. Pletnikov, Akira Sawa, Jean-Lud Cadet, Tao Wang
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Novelty-seeking behaviors and impulsivity are personality traits associated with several psychiatric illnesses including attention deficits hyperactivity disorders. The underlying neural mechanisms remain poorly understood. We produced and c
Externí odkaz:
https://doaj.org/article/dabac57c5e004138824d4951af477f0a
Autor:
Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108610- (2021)
Summary: Oligodendrocytes (OLs) are important for myelination and shuttling energy metabolites lactate and pyruvate toward axons through their expression of monocarboxylate transporter 1 (MCT1). Recent studies suggest that loss of OL MCT1 causes axon
Externí odkaz:
https://doaj.org/article/3365b3bdc34a429095f1971a8c5318cd
Autor:
Alexey V. Shevelkin, Chantelle E. Terrillion, Bagrat N. Abazyan, Tymoteusz J. Kajstura, Yan A. Jouroukhin, Gay L. Rudow, Juan C. Troncoso, David J. Linden, Mikhail V. Pletnikov
Publikováno v:
Neurobiology of Disease, Vol 103, Iss , Pp 144-153 (2017)
In addition to motor function, the cerebellum has been implicated in cognitive and social behaviors. Various structural and functional abnormalities of Purkinje cells (PCs) have been observed in schizophrenia and autism. As PCs express the gene Disru
Externí odkaz:
https://doaj.org/article/ca1f21a7b7144dda88c30d3c632f7a98
Autor:
Geetha Kannan, Joshua A. Crawford, ChunXia Yang, Kristin L. Gressitt, Chinezimuzo Ihenatu, Irina N. Krasnova, Jean Lud Cadet, Robert H. Yolken, Emily G. Severance, Mikhail V. Pletnikov
Publikováno v:
Neurobiology of Disease, Vol 91, Iss , Pp 307-314 (2016)
Background: Toxoplasma gondii is a pathogen implicated in psychiatric disorders. As elevated antibodies to T. gondii are also present in non-symptomatic individuals, we hypothesized that the age during first exposure to the pathogen may affect sympto
Externí odkaz:
https://doaj.org/article/e36d09c1dd724bf4830a5bd54136483a
Autor:
Meredith K. Loth, Judy Choi, Jennifer L. McGlothan, Mikhail V. Pletnikov, Martin G. Pomper, Tomás R. Guilarte
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 174-186 (2016)
Translocator protein (18 kDa), formerly known as the peripheral benzodiazepine receptor (PBR), has been extensively used as a biomarker of active brain disease and neuroinflammation. TSPO expression increases dramatically in glial cells, particularly
Externí odkaz:
https://doaj.org/article/05e678f30fbb460bb843d4d751a21128
Autor:
Mikhail V. Pletnikov, Dilorom Begmatova, Albert Pinhasov, Ulrike Weber-Stadlbauer, Kateryna Murlanova, Urs Meyer
Publikováno v:
Brain, Behavior, and Immunity. 99:3-8
Viral infections during pregnancy are associated with increased incidence of psychiatric disorders in offspring. The pathological outcomes of viral infection appear to be caused by the deleterious effects of innate immune response-associated factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fbd5de89daab4635a7d01e2ceabdd8
https://doi.org/10.1016/j.bbi.2021.09.004
https://doi.org/10.1016/j.bbi.2021.09.004
Autor:
Emese Prandovszky, Ye Li, Sarven Sabunciyan, Curtis B. Steinfeldt, Lauro Nathaniel Avalos, Kristin L. Gressitt, James R. White, Emily G. Severance, Mikhail V. Pletnikov, Jianchun Xiao, Robert H. Yolken
Publikováno v:
Scientifica, Vol 2018 (2018)
Toxoplasma gondii is an obligate intracellular parasite with worldwide distribution. Felines are the definitive hosts supporting the complete life cycle of T. gondii. However, other warm-blooded animals such as rodents and humans can also be infected
Externí odkaz:
https://doaj.org/article/1c53bf0a16b44fd8a344de2615618176
Publikováno v:
Scientifica, Vol 2018 (2018)
Infection with the protozoan parasite, Toxoplasma gondii (T. gondii), was linked to several psychiatric disorders. The exact mechanisms of a hypothesized contribution of T. gondii infection are poorly understood, and it appears that only a subset of
Externí odkaz:
https://doaj.org/article/acead8d955ba48c7aebabead5eaf4f49