Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Mikhail V, Gorshkov"'
Autor:
Anna A. Lobas, Elizaveta M. Solovyeva, Lev I. Levitsky, Anton O. Goncharov, Elena Y. Lyssuk, Sergey S. Larin, Sergei A. Moshkovskii, Mikhail V. Gorshkov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2466 (2023)
Alternative splicing is one of the main regulation pathways in living cells beyond simple changes in the level of protein expression. Most of the approaches proposed in proteomics for the identification of specific splicing isoforms require a prelimi
Externí odkaz:
https://doaj.org/article/948b5ea23e5b4e28914971ed7b3e2b1d
Autor:
Anastasia S. Nikitina, Anastasia V. Lipatova, Anton O. Goncharov, Anna A. Kliuchnikova, Mikhail A. Pyatnitskiy, Ksenia G. Kuznetsova, Azzam Hamad, Pavel O. Vorobyev, Olga N. Alekseeva, Marah Mahmoud, Yasmin Shakiba, Ksenia S. Anufrieva, Georgy P. Arapidi, Mark V. Ivanov, Irina A. Tarasova, Mikhail V. Gorshkov, Peter M. Chumakov, Sergei A. Moshkovskii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5244 (2022)
Cancer cell lines responded differentially to type I interferon treatment in models of oncolytic therapy using vesicular stomatitis virus (VSV). Two opposite cases were considered in this study, glioblastoma DBTRG-05MG and osteosarcoma HOS cell lines
Externí odkaz:
https://doaj.org/article/c684fc2217df4b81b868e2f7b8b6f803
Publikováno v:
Biochemistry (Moscow). 87:983-994
Chemical proteomics, emerging rapidly in recent years, has become a main approach to identifying interactions between the small molecules and proteins in the cells on a proteome scale and mapping the signaling and/or metabolic pathways activated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31810aacec124604b0c09e5a1d8350b2
https://doi.org/10.1134/s0006297922090103
https://doi.org/10.1134/s0006297922090103
Autor:
Lev I. Levitsky, Mark V. Ivanov, Anton O. Goncharov, Anna A. Kliuchnikova, Julia A. Bubis, Anna A. Lobas, Elizaveta M. Solovyeva, Mikhail A. Pyatnitskiy, Ruslan K. Ovchinnikov, Mikhail S. Kukharsky, Tatiana E. Farafonova, Svetlana E. Novikova, Victor G. Zgoda, Irina A. Tarasova, Mikhail V. Gorshkov, Sergei A. Moshkovskii
Publikováno v:
Journal of Proteome Research.
The proteogenomic search pipeline developed in this work has been applied for re-analysis of 40 publicly available shotgun proteomic datasets from various human tissues comprising more than 8,000 individual LC-MS/MS runs, of which 5442 .raw data file
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f00f3ab9bb6fce93dd4667c450a425
https://doi.org/10.1021/acs.jproteome.2c00740
https://doi.org/10.1021/acs.jproteome.2c00740
Current proteomics approaches rely almost exclusively on using positive ionization mode, which results in inefficient ionization of many acidic peptides. With an equal quantity of acidic and basic proteins and, correspondingly, the similar number for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49959338a5c948d78a0c676965c73fd1
https://doi.org/10.1101/2023.03.06.530802
https://doi.org/10.1101/2023.03.06.530802
Autor:
Elizaveta M. Solovyeva, Julia A. Bubis, Irina A. Tarasova, Anna A. Lobas, Mark V. Ivanov, Alexey A. Nazarov, Ilya A. Shutkov, Mikhail V. Gorshkov
Publikováno v:
Biochemistry. Biokhimiia. 87(11)
Abstract Protein quantitation in tissue cells or physiological fluids based on liquid chromatography/mass spectrometry is one of the key sources of information on the mechanisms of cell functioning during chemotherapeutic treatment. Information on si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274937fdaf5b3b639703b03f8c0bf0f2
https://pubmed.ncbi.nlm.nih.gov/36509723
https://pubmed.ncbi.nlm.nih.gov/36509723
Autor:
Mark V. Ivanov, Julia A. Bubis, Vladimir Gorshkov, Irina A. Tarasova, Lev I. Levitsky, Elizaveta M. Solovyeva, Anastasiya V. Lipatova, Frank Kjeldsen, Mikhail V. Gorshkov
Publikováno v:
Analytical chemistry. 94(38)
Recently, we presented the DirectMS1 method of ultrafast proteome-wide analysis based on minute-long LC gradients and MS1-only mass spectra acquisition. Currently, the method provides the depth of human cell proteome coverage of 2500 proteins at 1% f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cfdd32f5c4eccd97527fd8d6a01e93
https://pubmed.ncbi.nlm.nih.gov/36094425
https://pubmed.ncbi.nlm.nih.gov/36094425
Autor:
Yulia N. Nosova, Ilia V. Zenin, Varvara P. Maximova, Ekaterina M. Zhidkova, Kirill I. Kirsanov, Ekaterina A. Lesovaya, Anna A. Lobas, Mikhail V. Gorshkov, Olga N. Kovaleva, Elena R. Milaeva, Markus Galanski, Bernhard K. Keppler, Alexey A. Nazarov
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2017 (2017)
We present the synthesis and cytotoxic potencies of new Pt(IV) complexes with bexarotene, an anticancer drug that induces cell differentiation and apoptosis via selective activation of retinoid X receptors. In these complexes bexarotene is positioned
Externí odkaz:
https://doaj.org/article/fac7554cf940430381aa68a387731c73
Publikováno v:
Biochemistry (Moscow). 86:338-349
One of the main goals of quantitative proteomics is molecular profiling of cellular response to stress at the protein level. To perform this profiling, statistical analysis of experimental data involves multiple testing of a hypothesis about the equa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83224d33a85a2053abe927511ea45b8b
https://doi.org/10.1134/s0006297921030093
https://doi.org/10.1134/s0006297921030093
Autor:
Lev I. Levitsky, Ksenia G. Kuznetsova, Anna A. Kliuchnikova, Irina Y. Ilina, Anton O. Goncharov, Anna A. Lobas, Mark V. Ivanov, Vassili N. Lazarev, Rustam H. Ziganshin, Mikhail V. Gorshkov, Sergei A. Moshkovskii
Publikováno v:
Journal of proteome research. 21(6)
Mass spectrometry-based proteome analysis implies matching the mass spectra of proteolytic peptides to amino acid sequences predicted from genomic sequences. Reliability of peptide variant identification in proteogenomic studies is often lacking. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2654a768d0b048bb3974c7cc6b6be82
https://pubmed.ncbi.nlm.nih.gov/35536917
https://pubmed.ncbi.nlm.nih.gov/35536917