Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Mikhail Reibarkh"'
Autor:
Yunyi Wang, Aili Fan, Ryan D. Cohen, Guilherme Dal Poggetto, Zheng Huang, Haifeng Yang, Gary E. Martin, Edward C. Sherer, Mikhail Reibarkh, Xiao Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
The inability to distinguish two-bond from long-range HMBC correlation has historically impeded NMR structure elucidation. Here the authors developed a practical iHMBC methodology utilizing accurate isotope shift measurement to overcome this limitati
Externí odkaz:
https://doaj.org/article/4d1a5021e853492f8d7a31ff5b593c3d
Autor:
Ryan D. Cohen, Jared S. Wood, Yu-Hong Lam, Alexei V. Buevich, Edward C. Sherer, Mikhail Reibarkh, R. Thomas Williamson, Gary E. Martin
Publikováno v:
Molecules, Vol 28, Iss 6, p 2449 (2023)
Density functional theory (DFT) benchmark studies of 1H and 13C NMR chemical shifts often yield differing conclusions, likely due to non-optimal test molecules and non-standardized data acquisition. To address this issue, we carefully selected and me
Externí odkaz:
https://doaj.org/article/54ed81ada0c14c79b1a03ce3cb2aa001
Autor:
Rafael E. Luna, Haribabu Arthanari, Hiroyuki Hiraishi, Jagpreet Nanda, Pilar Martin-Marcos, Michelle A. Markus, Barak Akabayov, Alexander G. Milbradt, Lunet E. Luna, Hee-Chan Seo, Sven G. Hyberts, Amr Fahmy, Mikhail Reibarkh, David Miles, Patrick R. Hagner, Elizabeth M. O'Day, Tingfang Yi, Assen Marintchev, Alan G. Hinnebusch, Jon R. Lorsch, Katsura Asano, Gerhard Wagner
Publikováno v:
Cell Reports, Vol 1, Iss 6, Pp 689-702 (2012)
Recognition of the proper start codon on mRNAs is essential for protein synthesis, which requires scanning and involves eukaryotic initiation factors (eIFs) eIF1, eIF1A, eIF2, and eIF5. The carboxyl terminal domain (CTD) of eIF5 stimulates 43S preini
Externí odkaz:
https://doaj.org/article/6cf6f3e41f87402e85c1fa96880ae63b
Autor:
Lisa Lindqvist, Monika Oberer, Mikhail Reibarkh, Regina Cencic, Marie-Eve Bordeleau, Emily Vogt, Assen Marintchev, Junichi Tanaka, Francois Fagotto, Michael Altmann, Gerhard Wagner, Jerry Pelletier
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1583 (2008)
RNA helicases represent a large family of proteins implicated in many biological processes including ribosome biogenesis, splicing, translation and mRNA degradation. However, these proteins have little substrate specificity, making inhibition of sele
Externí odkaz:
https://doaj.org/article/aa2686c7919142e588b948d711ed23c7
Autor:
Nelo R. Rivera, Ryan D. Cohen, Si-Wei Zhang, Zachary E. X. Dance, Holst M. Halsey, Siqing Song, Xiaodong Bu, Mikhail Reibarkh, Hong Ren, Alfred Y. Lee, Darryl Chang, Sachin Lohani
Publikováno v:
Organic Process Research & Development. 27:286-294
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4808f18942b26079e70ab9fbc5687256
https://doi.org/10.1021/acs.oprd.2c00313
https://doi.org/10.1021/acs.oprd.2c00313
Publikováno v:
Journal of Medicinal Chemistry. 66:1955-1971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbcb5bf80b2c763f1e696cc744337efa
https://doi.org/10.1021/acs.jmedchem.2c01744
https://doi.org/10.1021/acs.jmedchem.2c01744
Autor:
Nadine Kuhl, Ben W. H. Turnbull, Yining Ji, Reed T. Larson, Michael Shevlin, Christopher K. Prier, Cheol K. Chung, Richard Desmond, Erik Guetschow, Cyndi Qixin He, Tetsuji Itoh, Jeffrey T. Kuethe, Justin A. Newman, Mikhail Reibarkh, Nelo R. Rivera, Gao Shang, Zhixun Wang, Daniel Zewge, David A. Thaisrivongs
Publikováno v:
Green Chemistry. 25:606-613
The development of a protecting group-free, 2-step synthesis of 5-amino-2-hydroxymethyltetrahydropyran 1a from biorenewable Cyrene™ is described which renders access to BTK-inhibitor nemtabrutinib (2) more efficient and sustainable.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76254159f72e72785c230763f61657ab
https://doi.org/10.1039/d2gc04117k
https://doi.org/10.1039/d2gc04117k
Autor:
Matthew S. Winston, Marc Poirier, Zhijian Liu, Feng Peng, Guy R. Humphrey, John A. McIntosh, Mikhail Reibarkh, Fengqiang Wang, Erik D. Guetschow, Steve Castro, Erik Hoyt, David J. Lamberto, Kevin Sirk
Publikováno v:
Organic Process Research & Development. 27:179-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc86545e85638ae22f318904489ad7f
https://doi.org/10.1021/acs.oprd.2c00327
https://doi.org/10.1021/acs.oprd.2c00327
Autor:
Ronald C. Crouch, Marius Pelmuş, Jeffrey G. Raab, Evgeny Tischenko, Michael Frey, Yunyi Wang, Mikhail Reibarkh, R. Thomas Williamson, Gary E. Martin
Publikováno v:
Magnetic Resonance in Chemistry. 61:169-179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c771ffe0eeaf68e8e08b953d7fe4a3
https://doi.org/10.1002/mrc.5324
https://doi.org/10.1002/mrc.5324
Autor:
Jared S. Wood, Guilherme Dal Poggetto, Xiao Wang, Mikhail Reibarkh, R. Thomas Williamson, Ryan D. Cohen
Publikováno v:
Magnetic Resonance in Chemistry. 61:22-31
Chloride is the most common counterion used to improve aqueous solubility and enhance stability of small molecule active pharmaceutical ingredients. While several analytical techniques, such as titration, HPLC with charged aerosol detection, and ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e2721b1f27230dee6b7ba1c4e13e1f
https://doi.org/10.1002/mrc.5316
https://doi.org/10.1002/mrc.5316