Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mikhail Ognenovski"'
Autor:
Patrick Coit, Shaylynn Miller, W. Joseph McCune, Mikhail Ognenovski, Paul Renauer, Pei-Suen Tsou, Elizabeth Gensterblum, Nathan C Kilian, Faith M. Strickland, Kathleen Maksimowicz-McKinnon, Amr H. Sawalha, Jonathan D. Wren, Emily E. Lewis, Bruce C. Richardson
Objective The goal of this study was to comprehensively characterize CD4+CD28+ T cells overexpressing CD11a and KIR genes, and examine the relationship between this T cell subset, genetic risk, and disease activity in lupus. Methods The size of the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5cd416cf6a0f6654138a3c02f7ea79
https://europepmc.org/articles/PMC5821123/
https://europepmc.org/articles/PMC5821123/
Autor:
Elizabeth Gensterblum, Haner Direskeneli, Kenneth M. Kaufman, Bruno Casali, Paul Renauer, Jörg Henes, Theodoros Xenitidis, Carlo Salvarani, Amr H. Sawalha, Ina Kötter, Mikhail Ognenovski
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 68(5)
OBJECTIVE Behcet's disease (BD) is a systemic inflammatory disease with an incompletely understood etiology. Despite the identification of multiple common genetic variants associated with BD, rare genetic variants have been less explored. We undertoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6749e9ded65da5b5e4f3ddc5cdd2616a
https://pubmed.ncbi.nlm.nih.gov/26662719
https://pubmed.ncbi.nlm.nih.gov/26662719
Autor:
Mikhail Ognenovski, Jonathan D. Wren, Srilakshmi Yalavarthi, Patrick Coit, Sarfaraz Hasni, Wenpu Zhao, Mariana J. Kaplan, Amr H. Sawalha
Publikováno v:
Journal of autoimmunity. 58
Recent evidence suggests that neutrophils play an important role in the pathogenesis of lupus. The goal of this study was to characterize the epigenetic architecture, by studying the DNA methylome, of neutrophils and low density granulocytes (LDGs) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d347f88c8f8e2e7991207a8dbeae9833
https://pubmed.ncbi.nlm.nih.gov/25687179
https://pubmed.ncbi.nlm.nih.gov/25687179
Publikováno v:
Lupus Science & Medicine
Objective Defective or inefficient DNA double-strand break (DSB) repair results in failure to preserve genomic integrity leading to apoptotic cell death, a hallmark of systemic lupus erythematosus (SLE). Compelling evidence linked environmental facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e00dbbf70a8826616d5dde7c4250d7
https://doi.org/10.1136/lupus-2016-000148
https://doi.org/10.1136/lupus-2016-000148
Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity
Autor:
Amr H. Sawalha, Elizabeth Gensterblum, Mikhail Ognenovski, Patrick Coit, Jonathan D. Wren, Kathleen Maksimowicz-McKinnon
Publikováno v:
Epigenetics & Chromatin
Background Genetic and epigenetic variability contributes to the susceptibility and pathogenesis of autoimmune diseases. T cells play an important role in several autoimmune conditions, including lupus, which is more common and more severe in people
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52db356109b42bfed1d36d6d7e419a95