Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies

Autor: Mikhail M. Zaripov, Albert A. Rizvanov, Regina Mirgayazova, Emil Bulatov, Ekaterina Zmievskaya, Raniya Khadiullina, Irina Ganeeva, V. V. Chasov, Aigul Valiullina

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)

Transcription factor and oncosuppressor protein p53 is considered as one of the most promising molecular targets that remains a high-hanging fruit in cancer therapy. TP53 gene encoding the p53 protein is known to be the most frequently mutated gene i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef5e150a6c58a244bb578e79003f9ff
http://europepmc.org/articles/PMC8411701

Fluorescent tagging the NS1 protein in yellow fever virus: Replication-capable viruses which produce the secretory GFP-NS1 fusion protein

Autor: Alexandr Shevtsov, Shustov Av, Laura R. Syzdykova, Stephan Binke, Erlan Ramanculov, Assylbek Zhylkibayev, Viktoriya V. Keyer, Mikhail M. Zaripov

Publikováno v: Virus Research. 294:198291

Yellow fever virus, the prototype in the genus Flavivirus, was used to develop viruses in which the nonstructural protein NS1 is genetically fused to GFP in the context of viruses capable of autonomous replication. The GFP-tagging of NS1 at the amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c507566b8e31c531f2974bf383ffe3
https://doi.org/10.1016/j.virusres.2020.198291

Promising New Tools for Targeting p53 Mutant Cancers: Humoral and Cell-Based Immunotherapies.

Autor: Chasov V; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Zaripov M; Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Russia., Mirgayazova R; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Khadiullina R; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Zmievskaya E; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Ganeeva I; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Valiullina A; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Rizvanov A; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia., Bulatov E; Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Aug 13; Vol. 12, pp. 707734. Date of Electronic Publication: 2021 Aug 13 (Print Publication: 2021).