Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mikhail Lomonosov"'
Autor:
Mikhail Lomonosov, El Kahina Meziane, Hongtao Ye, David E Nelson, Suzanne J Randle, Heike Laman
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21165 (2011)
Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner. Here we present new evide
Externí odkaz:
https://doaj.org/article/153ac863f59348c4b49bbdc5327612de
Autor:
Anfisa Popova, Alexander Andreev-Andrievskiy, Evgeniia Lagereva, Mikhail Lomonosov, Ramiz Salimov, Pierre Clément, Dmitriy Golikov
Publikováno v:
The journal of sexual medicine. 14(3)
Introduction Low sexual desire is a frequent sexual problem in women, with only one drug for the condition approved by the Food and Drug Administration. Aim To evaluate the ability of a novel synthetic peptide, BP101, to facilitate sexual behavior af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cdbcc6c1d07c65d6e98082f1678edf
https://pubmed.ncbi.nlm.nih.gov/28189563
https://pubmed.ncbi.nlm.nih.gov/28189563
Publikováno v:
Genes & Development. 17:3017-3022
How dividing mammalian cells overcome blocks to DNA replication by DNA damage, depleted nucleotide pools, or template-bound proteins is unclear. Here, we show that the response to blocked replication requires BRCA2, a suppressor of human breast cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a112112417cc21fedd80eb78911c7c
https://doi.org/10.1101/gad.279003
https://doi.org/10.1101/gad.279003
Publikováno v:
Journal of cell science. 124(Pt 13)
Fbxo7 is an unusual F-box protein because most of its interacting proteins are not substrates for ubiquitin-mediated degradation. Fbxo7 directly binds p27 and Cdk6, enhances the level of cyclin D–Cdk6 complexes, and its overexpression causes Cdk6-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d417d63c9bd95cd2e932b1048acc0826
https://pubmed.ncbi.nlm.nih.gov/21652635
https://pubmed.ncbi.nlm.nih.gov/21652635
Autor:
Suzanne J. Randle, El Kahina Meziane, David E. Nelson, Mikhail Lomonosov, Hongtao Ye, Heike Laman
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21165 (2011)
PLoS ONE
PLoS ONE
Fbxo7 is an unusual F box protein that augments D-type cyclin complex formation with Cdk6, but not Cdk4 or Cdk2, and its over-expression has been demonstrated to transform immortalised fibroblasts in a Cdk6-dependent manner. Here we present new evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac73569775fda4498bd819f73427c243
https://www.repository.cam.ac.uk/handle/1810/278552
https://www.repository.cam.ac.uk/handle/1810/278552
Autor:
Rebecca Kirk, Judith Murray-Rust, Mikhail Lomonosov, Heike Laman, Neil Q. McDonald, Phillip P. Knowles, El Kahina Meziane
Publikováno v:
The Journal of biological chemistry. 283(32)
F-box proteins are the substrate-recognition components of the Skp1-Cul1-F box protein (SCF) E3 ubiquitin ligases. Here we report a structural relationship between Fbxo7, a component of the SCF(Fbxo7) E3 ligase, and the proteasome inhibitor PI31. SCF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827c2ed3d3604f413aad780e32fce1f4
https://pubmed.ncbi.nlm.nih.gov/18495667
https://pubmed.ncbi.nlm.nih.gov/18495667
Autor:
Norman J. Maitland, Marina Kriajevska, Klaus Hansen, Mikhail Lomonosov, Igor B. Bronstein, Eugene Lukanidin, Svetlana Tarabykina, Georgii P. Georgiev
Publikováno v:
The Journal of biological chemistry. 273(16)
Mts1 protein (S100A4 according to a new classification) has been implicated in the formation of the metastatic phenotype via regulation of cell motility and invasiveness. Previously we have demonstrated that Mts1 protein interacted with the heavy cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e10586421c420aff4bb11bd85e918b
https://pubmed.ncbi.nlm.nih.gov/9545325
https://pubmed.ncbi.nlm.nih.gov/9545325
Publikováno v:
Cancer Research. 71:LB-189
The F-box protein Fbxo7 specifically enhances the levels of cyclin D-Cdk6 complexes, the predominant G1 kinase active in hematopoietic cells, which is a commonly activated oncogenic pathway in lymphoid neoplasms. In addition, Fbxo7 is itself abundant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f0ced6a76ab01cbed06b1b1c5cfe12a
https://doi.org/10.1158/1538-7445.am2011-lb-189
https://doi.org/10.1158/1538-7445.am2011-lb-189