Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Mikhail Liskovykh"'
Autor:
Nikolay V. Goncharov, Valeria A. Kovalskaia, Alexander O. Romanishin, Nikita A. Shved, Andrei S. Belousov, Vladlena S. Tiasto, Valeriia S. Gulaia, Vidushi S. Neergheen, Nawraj Rummun, Mikhail Liskovykh, Vladimir Larionov, Natalay Kouprina, Vadim V. Kumeiko
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Human artificial chromosomes (HACs) have provided a useful tool to study kinetochore structure and function, gene delivery, and gene expression. The HAC propagates and segregates properly in the cells. Recently, we have developed an experimental high
Externí odkaz:
https://doaj.org/article/939e5a9d4efb4137a2722f530ed11179
Autor:
Jung-Hyun Kim, Vladimir N. Noskov, Aleksey Y. Ogurtsov, Ramaiah Nagaraja, Nikolai Petrov, Mikhail Liskovykh, Brian P. Walenz, Hee-Sheung Lee, Natalay Kouprina, Adam M. Phillippy, Svetlana A. Shabalina, David Schlessinger, Vladimir Larionov
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units within an individual nucleolar or
Externí odkaz:
https://doaj.org/article/3fe958d0148f47c1a2f569bdf90256d7
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Microcell-mediated chromosome transfer (MMCT) technology enables individual mammalian chromosomes, megabase-sized chromosome fragments, or mammalian artificial chromosomes that include human artificial chromosomes (HACs) and mouse artificial chromoso
Externí odkaz:
https://doaj.org/article/91df6c543cec4eecbb2ad5dea49cabcb
Autor:
Mikhail Liskovykh, Ilya Chuykin, Ashish Ranjan, Dina Safina, Elena Popova, Elena Tolkunova, Valentina Mosienko, Julia M Minina, Natalia S Zhdanova, John J Mullins, Michael Bader, Natalia Alenina, Alexey Tomilin
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27345 (2011)
The rat represents an important animal model that, in many respects, is superior to the mouse for dissecting behavioral, cardiovascular and other physiological pathologies relevant to humans. Derivation of induced pluripotent stem cells from rats (ri
Externí odkaz:
https://doaj.org/article/74b1ba3a139f4c929b2668fb6f3c4ba8
Autor:
Mikhail Liskovykh, Nikolai S. Petrov, Vladimir N. Noskov, Hiroshi Masumoto, William C. Earnshaw, David Schlessinger, Svetlana A. Shabalina, Vladimir Larionov, Natalay Kouprina
Publikováno v:
Liskovykh, M, Petrov, N S, Noskov, V N, Masumoto, H, Earnshaw, W C, Schlessinger, D, Shabalina, S A, Larionov, V & Kouprina, N 2023, ' Actively transcribed rDNA and distal junction (DJ) sequence are involved in association of NORs with nucleoli ', Cellular and Molecular Life Sciences, vol. 80, no. 5, 121 . https://doi.org/10.1007/s00018-023-04770-3
Although they are organelles without a limiting membrane, nucleoli have an exclusive structure, built upon the rDNA-rich acrocentric short arms of five human chromosomes (nucleolar organizer regions or NORs). This has raised the question: what are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c6d0a17bc08a5f209032b9cf607d0c
https://hdl.handle.net/20.500.11820/bf60b92a-f13e-4419-90da-6aaf6adb3a3a
https://hdl.handle.net/20.500.11820/bf60b92a-f13e-4419-90da-6aaf6adb3a3a
Autor:
Natalay Kouprina, Vladimir Larionov, William C. Earnshaw, Yves Pommier, Marie-Paule Teulade-Fichou, Hiroshi Masumoto, Mitsuo Oshimura, Jung-Hyun Kim, Emma Peat, Mikhail Liskovykh, Mar Carmena, Hee-Sheung Lee
The targeting of telomerase and telomere maintenance mechanisms represents a promising therapeutic approach for various types of cancer. In this work, we designed a new protocol to screen for and rank the efficacy of compounds specifically targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::707a0eac29a88e45359137aadf7d18b9
https://doi.org/10.1158/0008-5472.c.6510540.v1
https://doi.org/10.1158/0008-5472.c.6510540.v1
Autor:
Natalay Kouprina, Vladimir Larionov, William C. Earnshaw, Yves Pommier, Marie-Paule Teulade-Fichou, Hiroshi Masumoto, Mitsuo Oshimura, Jung-Hyun Kim, Emma Peat, Mikhail Liskovykh, Mar Carmena, Hee-Sheung Lee
14 Supplementary Figures and 2 Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6369effd13b0cd3a51d724d4b82293
https://doi.org/10.1158/0008-5472.22420032
https://doi.org/10.1158/0008-5472.22420032
Autor:
Mikhail Liskovykh, Nikolai S. Petrov, Vladimir N. Noskov, Hiroshi Masumoto, William C. Earnshaw, David Schlessinger, Svetlana A. Shabalina, Vladimir Larionov, Natalay Kouprina
Although they are organelles without a limiting membrane, nucleoli have an exclusive structure, built upon the rDNA-rich acrocentric short arms of five human chromosomes (nucleolar organizer regions or NORs). This has raised the question: what are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7dfc9dfe2ae5b35de6e82d1ed5b407e
https://doi.org/10.21203/rs.3.rs-1801825/v1
https://doi.org/10.21203/rs.3.rs-1801825/v1
Autor:
Natalay Kouprina, Marie-Paule Teulade-Fichou, Yves Pommier, N. S. Petrov, Vladimir Larionov, Mikhail Liskovykh, William C. Earnshaw, Hee-Sheung Lee, Hiroshi Masumoto
Publikováno v:
Petrov, N S, Lee, H-S, Liskovykh, M, Teulade-Fichou, M-P, Masumoto, H, Earnshaw, W C, Pommier, Y, Larionov, V & Kouprina, N 2021, ' Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells ', Oncotarget, vol. 12, pp. 1444-1456 . https://doi.org/10.18632/oncotarget.28020
Oncotarget
Oncotarget
Background Telomerase/telomere-targeting therapy is a potentially promising approach for cancer treatment because even transient telomere dysfunction can induce chromosomal instability (CIN) and may be a barrier to tumor growth. Method: We recently d
Autor:
N. S. Petrov, Aleksey Y. Ogurtsov, Natalay Kouprina, Vladimir N. Noskov, David Schlessinger, Hee-Sheung Lee, Jung-Hyun Kim, Adam M. Phillippy, Ramaiah Nagaraja, Svetlana A. Shabalina, Vladimir Larionov, Mikhail Liskovykh, Brian P. Walenz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
The rDNA clusters and flanking sequences on human chromosomes 13, 14, 15, 21 and 22 represent large gaps in the current genomic assembly. The organization and the degree of divergence of the human rDNA units within an individual nucleolar organizer r