Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mikhail L. Vorobev"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-11 (2024)
Abstract The current focus in oncology research is the translational control of cancer cells as a major mechanism of cellular plasticity. Recent evidence has prompted a reevaluation of the role of the mTOR pathway in cancer development leading to new
Externí odkaz:
https://doaj.org/article/8dfb6c9433c740deb48558c250cf8b25
Autor:
Natalia N. Bezborodkina, Andrei V. Stepanov, Mikhail L. Vorobev, Grigory I. Stein, Sergey V. Okovityi, Boris N. Kudryavtsev
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9263 (2022)
Glycogen is an easily accessible source of energy for various processes. In hepatocytes, it can be found in the form of individual molecules (β-particles) and their agglomerates (α-particles). The glycogen content in hepatocytes depends on the phys
Externí odkaz:
https://doaj.org/article/4ef815d29b0e4fa0a674744743f7ba03
Publikováno v:
Biochemical and Biophysical Research Communications. 552:78-83
Autophagy is known to play a critical role in the early stages of embryogenesis including the formation of blastocyst. The existence of p53 protein-deficient mice may identify that p53 is not indispensable for the activation of autophagy in pluripote
Publikováno v:
Cell and Tissue Biology. 14:332-340
Embryonic stem cells (ESCs), and their artificial counterparts, induced pluripotent stem cells (iPSCs) give rise to all differentiated cell types in adult organism.Therefore, pluripotent cells are an inexhaustible cell source for regenerative medicin
Autor:
Andrei A. Karpov, Andrei V. Stepanov, Olga V. Rogoza, Mikhail L. Vorobev, G. A. Sakuta, B. N. Kudryavtsev, E. V. Baidyuk
Publikováno v:
Cytometry Part A. 95:730-736
Ischemic lesions of the heart, including myocardial infarction, are the most common pathologies of human cardiovascular system. Despite all the research and achievements of medicine in this field, the mortality from this disease remains heavy. Theref
Publikováno v:
Biochemical and biophysical research communications. 532(2)
Defective pluripotent cells are removed from embryos prior to differentiation, presumably due to upregulation of the p53 pathway. However, the mechanism underlying p53 protein activation is still unknown. Embryonic stem cells (ESCs), corresponding to
Autor:
B. N. Kudryavtsev, Anna Yu. Chestnova, Mikhail L. Vorobev, Andrei V. Stepanov, N N Bezborodkina, G.I. Stein
Publikováno v:
Journal of Molecular Structure. 1228:129770
It is currently thought that a full glycogen molecule (β-particle) has a spherical shape with 12 concentric tiers of glucose residues with glycogenin in the center and diameter of about 42 nm. However, the spatial structure of the β-particle remain
Publikováno v:
Cytometry Part A. 89:357-364
Background & aims Hepatocytes differ from one another by the degree of the ploidy, size, position in the liver lobule, and level of the DNA-synthetic processes. It is believed, that the cell size exerts substantial influence on the metabolism of the
Publikováno v:
Biochemistry. Biokhimiia. 83(5)
Glycogen is a strongly branched polymer of α-D-glucose, with glucose residues in the linear chains linked by 1→4-bonds (~93% of the total number of bonds) and with branching after every 4-8 residues formed by 1→6-glycosidic bonds (~7% of the tot
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 89(4)
Hepatocytes differ from one another by the degree of the ploidy, size, position in the liver lobule, and level of the DNA-synthetic processes. It is believed, that the cell size exerts substantial influence on the metabolism of the hepatocytes and th