Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mikhail L. Gishizky"'
Autor:
Pier Paolo Di Fiore, Giulio F. Draetta, Mikhail L. Gishizky, Giuseppe Viale, Francesco Pallotti, Renzo Boldorini, Manuela Nebuloni, Marco Bianchi, Micaela Quarto, Stefano Confalonieri, Paolo Giovanni Nuciforo, Maria Capra
Supplementary Table 1 from Frequent Alterations in the Expression of Serine/Threonine Kinases in Human Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626cb720f59b0c4c58cd3eaec9198a99
https://doi.org/10.1158/0008-5472.22364858
https://doi.org/10.1158/0008-5472.22364858
Autor:
Pier Paolo Di Fiore, Giulio F. Draetta, Mikhail L. Gishizky, Giuseppe Viale, Francesco Pallotti, Renzo Boldorini, Manuela Nebuloni, Marco Bianchi, Micaela Quarto, Stefano Confalonieri, Paolo Giovanni Nuciforo, Maria Capra
Protein kinases constitute a large family of regulatory enzymes involved in the homeostasis of virtually every cellular process. Subversion of protein kinases has been frequently implicated in malignant transformation. Within the family, serine/threo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e06d2bf953db0608724836457bb9760
https://doi.org/10.1158/0008-5472.c.6494402.v1
https://doi.org/10.1158/0008-5472.c.6494402.v1
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181464 (2017)
We report here the cloning of native high affinity anti-TIM-3 and anti-KIR IgG monoclonal antibodies (mAbs) from peripheral blood mononuclear cells (PBMC) of healthy human donors. The cells that express these mAbs are rare, present at a frequency of
Externí odkaz:
https://doaj.org/article/28f99844ab4645af9cf951a8f9bd6036
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 7, p e0181464 (2017)
PLoS ONE, Vol 12, Iss 7, p e0181464 (2017)
We report here the cloning of native high affinity anti-TIM-3 and anti-KIR IgG monoclonal antibodies (mAbs) from peripheral blood mononuclear cells (PBMC) of healthy human donors. The cells that express these mAbs are rare, present at a frequency of
Autor:
Marco Bianchi, Pier Paolo Di Fiore, Maria Capra, Paolo Nuciforo, Manuela Nebuloni, Giuseppe Viale, Stefano Confalonieri, Giulio Draetta, Renzo Boldorini, Francesco Pallotti, M Quarto, Mikhail L. Gishizky
Publikováno v:
Cancer Research. 66:8147-8154
Protein kinases constitute a large family of regulatory enzymes involved in the homeostasis of virtually every cellular process. Subversion of protein kinases has been frequently implicated in malignant transformation. Within the family, serine/threo
Autor:
Carrie Blanchette, Xiao-Fan Wang, Xuefang Bai, Ryan M. Anderson, Rong Shao, Tongyun Dang, Mikhail L. Gishizky, Jeffrey R. Marks, Shideng Bao
Publikováno v:
Molecular and Cellular Biology. 24:3992-4003
The development of human cancers is a multistep complex process by which cancer cells acquire the ability to overcome the restraints imposed by the surrounding normal tissue microenvironment (7). This process is believed to be driven by the intrinsic
Publikováno v:
Journal of Biological Chemistry. 278:18221-18228
The Ste20 family of serine/threonine kinases plays an important role in numerous cellular functions such as growth, apoptosis, and morphogenesis. We have identified a previously cloned but uncharacterized family member termed Stk10, which is a human
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10889-10893
Growth factor-binding protein 2 (Grb2) is an adaptor protein that links tyrosine kinases to Ras. BCR-ABL is a tyrosine kinase oncoprotein that is implicated in the pathogenesis of Philadelphia chromosome (Ph1)-positive leukemias. Grb2 forms a complex
Autor:
Da Ngyen, Angeles Estelles, Yifan Yang, Manfred Heideker, Evelene Lomongsod, Lawrence M. Kauvar, Robert A. Stephenson, Mikhail L. Gishizky, Stefan Ryser, Jianzhong Zhzng, Keyi Liu
Publikováno v:
Cancer Research. 76:594-594
The immunosurveillance/immunoediting theory postulates that tumor growth is repressed in healthy individuals through the activation of adaptive and innate immune mechanisms. The clinical success of antibodies that target inhibitory checkpoint pathway
Autor:
Ann Marie Pendergast, Andreas Batzer, Craig H. Bassing, Nanxin Li, Mikhail L. Gishizky, Channing J. Der, Joseph Schlessinger, Lawrence A. Quilliam, Kelly M. Rabun, Larry D. Cripe, Zonghan Dai
Publikováno v:
Cell. 75:175-185
Summary BCR-ABL is a chimeric oncoprotein that exhibits deregulated tyrosine kinase activity and is implicated in the pathogenesis of Philadelphia chromosome (Ph 1 )-positive human leukemias. Sequences within the first exon of BCR are required to act