Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Mikhail KA"'
Autor:
Yasmine Nahal, Janosch Menke, Julien Martinelli, Markus Heinonen, Mikhail Kabeshov, Jon Paul Janet, Eva Nittinger, Ola Engkvist, Samuel Kaski
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-24 (2024)
Abstract Machine learning (ML) systems have enabled the modelling of quantitative structure–property relationships (QSPR) and structure-activity relationships (QSAR) using existing experimental data to predict target properties for new molecules. T
Externí odkaz:
https://doaj.org/article/f323574a1df848b7b1dac1ab4505639a
Autor:
Xiaoran Liu, Jong-Woo Kim, Yao Wang, Michael Terilli, Xun Jia, Mikhail Kareev, Shiyu Peng, Fangdi Wen, Tsung-Chi Wu, Huyongqing Chen, Wanzheng Hu, Mary H. Upton, Jungho Kim, Yongseong Choi, Daniel Haskel, Hongming Weng, Philip J. Ryan, Yue Cao, Yang Qi, Jiandong Guo, Jak Chakhalian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract The pyrochlore iridates have become ideal platforms to unravel fascinating correlated and topological phenomena that stem from the intricate interplay among strong spin-orbit coupling, electronic correlations, lattice with geometric frustrat
Externí odkaz:
https://doaj.org/article/b3fca8f31ee9476495941c33102e5661
Autor:
Majd Mardini, Mikhail Kazancev, Elina Ivoilova, Victoria Utkina, Anastasia Vlasova, Yakov Demurin, Alexander Soloviev, Ilya Kirov
Publikováno v:
Plant Methods, Vol 20, Iss 1, Pp 1-13 (2024)
Abstract Virus-Induced Gene Silencing (VIGS) is a versatile tool in plant science, yet its application to non-model species like sunflower demands extensive optimization due to transformation challenges. In this study, we aimed to elucidate the facto
Externí odkaz:
https://doaj.org/article/88d85f44f96d46feacf88b1e2a3b9862
Autor:
Janosch Menke, Yasmine Nahal, Esben Jannik Bjerrum, Mikhail Kabeshov, Samuel Kaski, Ola Engkvist
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract One challenge that current de novo drug design models face is a disparity between the user’s expectations and the actual output of the model in practical applications. Tailoring models to better align with chemists’ implicit knowledge, e
Externí odkaz:
https://doaj.org/article/ad1a3b4ac528469290d1aca82bde37c2
Autor:
Melissa Ward Jones, Joachim Otto Habeck, Mathias Ulrich, Susan Crate, Glenna Gannon, Tobias Schwoerer, Benjamin Jones, Mikhail Kanevskiy, Prashant Baral, Amina Maharjan, Jakob Steiner, Andrew Spring, Mindy Jewell Price, David Bysouth, Bruce C. Forbes, Mariana Verdonen, Timo Kumpula, Jens Strauss, Torben Windirsch, Christopher Poeplau, Yuri Shur, Benjamin Gaglioti, Nicholas Parlato, Fulu Tao, Merritt Turetsky, Stephanie Grand, Adrian Unc, Nils Borchard
Publikováno v:
Arctic, Antarctic, and Alpine Research, Vol 56, Iss 1 (2024)
Permafrost-agroecosystems include all cultivation and pastoral activities in areas underlain by permafrost. These systems support local livelihoods and food production and are rarely considered in global agricultural studies but may become more relev
Externí odkaz:
https://doaj.org/article/03e2cc3627984c7999d780e557ca1393
Autor:
Mikhail Kanarskii, Julia Nekrasova, Ekaterina Kondratieva, Ilya Borisov, Elena Simenel, Yurii Sviryaev, Pranil Pradhan, Kirill Gorshkov, Alexander Shestopalov, Marina Petrova
Publikováno v:
Sleep Medicine: X, Vol 7, Iss , Pp 100101- (2024)
Annotation (Abstract): Aim: The aim of our study is to assess circadian rhythms in patients with chronic critical illness due to severe brain injury in intensive care unit by establishing the relation between melatonin and cortisol secretion, conside
Externí odkaz:
https://doaj.org/article/7eebc68b57e142608ef880450c14f4a1
Autor:
Mikhail Karpov, Nicolai Strizhov, Ludmila Novikova, Tatyana Lobastova, Sergey Khomutov, Andrei Shutov, Alexey Kazantsev, Marina Donova
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Pregnenolone and progesterone are the life-important steroid hormones regulating essential vital functions in mammals, and widely used in different fields of medicine. Microbiological production of these compounds from sterols is
Externí odkaz:
https://doaj.org/article/f373070722e34c05aafea9f4a7557cfe
Autor:
Iuliia Y. Nekrasova, Andrey V. Grechko, Mikhail Kanarskii, Ilya V. Borisov, Pranil Pradhan, Aleksey V. Mukhin, Dmitry S. Yankevich, Marina V. Petrova
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 3, Pp 31-40 (2023)
Introduction. There is a worldwide lack of statistical data about the patients with chronic disorders of consciousness (DOC). In Russia, there are no such data at all. Objective: to perform the first study in Russia to assess the survival rate and
Externí odkaz:
https://doaj.org/article/c50355fe2b8f4b8b95739280c8792134
Autor:
Christine Howard, Emma-Liina Marjakangas, Alejandra Morán-Ordóñez, Pietro Milanesi, Aleksandre Abuladze, Karen Aghababyan, Vitalie Ajder, Volen Arkumarev, Dawn E. Balmer, Hans-Günther Bauer, Colin M. Beale, Taulant Bino, Kerem Ali Boyla, Ian J. Burfield, Brian Burke, Brian Caffrey, Tomasz Chodkiewicz, Juan Carlos Del Moral, Vlatka Dumbovic Mazal, Néstor Fernández, Lorenzo Fornasari, Bettina Gerlach, Carlos Godinho, Sergi Herrando, Christina Ieronymidou, Alison Johnston, Mihailo Jovicevic, Mikhail Kalyakin, Verena Keller, Peter Knaus, Dražen Kotrošan, Tatiana Kuzmenko, Domingos Leitão, Åke Lindström, Qenan Maxhuni, Tomaž Mihelič, Tibor Mikuska, Blas Molina, Károly Nagy, David Noble, Ingar Jostein Øien, Jean-Yves Paquet, Clara Pladevall, Danae Portolou, Dimitrije Radišić, Saša Rajkov, Draženko Z. Rajković, Liutauras Raudonikis, Thomas Sattler, Darko Saveljić, Paul Shimmings, Jovica Sjenicic, Karel Šťastný, Stoycho Stoychev, Iurii Strus, Christoph Sudfeldt, Elchin Sultanov, Tibor Szép, Norbert Teufelbauer, Danka Uzunova, Chris A. M. van Turnhout, Metodija Velevski, Thomas Vikstrøm, Alexandre Vintchevski, Olga Voltzit, Petr Voříšek, Tomasz Wilk, Damaris Zurell, Lluís Brotons, Aleksi Lehikoinen, Stephen G. Willis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Climate change has been associated with both latitudinal and elevational shifts in species’ ranges. The extent, however, to which climate change has driven recent range shifts alongside other putative drivers remains uncertain. Here, we us
Externí odkaz:
https://doaj.org/article/451d648b350e49c094829238fa090dfc
Autor:
Vincent Martin, Denis Carre, Heloise Bilbault, Sebastien Oster, Lorenzo Limana, Florian Sebal, Christine Favre-Guilmard, Mikhail Kalinichev, Christian Leveque, Virginie Boulifard, Catherine George, Stephane Lezmi
Publikováno v:
Toxins, Vol 16, Iss 5, p 225 (2024)
Botulinum neurotoxins E (BoNT/E) and A (BoNT/A) act by cleaving Synaptosome-Associated Protein 25 (SNAP25) at two different C-terminal sites, but they display very distinct durations of action, BoNT/E being short acting and BoNT/A long acting. We inv
Externí odkaz:
https://doaj.org/article/da39eda0c3fa4bd69e626c7a3f507400