Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Mikhail I . Voevoda"'
Autor:
Dinara E. Ivanoshchuk, Alla K. Ovsyannikova, Svetlana V. Mikhailova, Elena V. Shakhtshneider, Emil S. Valeev, Oksana D. Rymar, Pavel S. Orlov, Mikhail I. Voevoda
Publikováno v:
Атеросклероз, Vol 17, Iss 4, Pp 11-19 (2022)
Maturity onset diabetes of the young is a dominantly inherited form of monogenic diabetes, diagnosed mainly before the age of 35 years. Mutations in the HNF1A and HNF4A genes are associated with diabetes mellitus of the HNF1A-MODY and HNF4A-MODY subt
Externí odkaz:
https://doaj.org/article/77b9ff319d8048d7abccddba4de34473
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S3, Pp 1-23 (2019)
Abstract Background Tick-borne encephalitis (TBE) is a viral infectious disease caused by tick-borne encephalitis virus (TBEV). TBEV infection is responsible for a variety of clinical manifestations ranging from mild fever to severe neurological illn
Externí odkaz:
https://doaj.org/article/adf71291eac749b586b90c7365f3148f
Publikováno v:
BMC Medical Genetics, Vol 20, Iss S1, Pp 29-34 (2019)
Abstract Background Population structure is an important factor in the genetic association studies but often remains underexplored for many human populations. We identified exome variants in 39 Siberian Caucasian individuals from Novosibirsk, Russia
Externí odkaz:
https://doaj.org/article/2dcc42e4c28d47d391a1413886a49c3e
Autor:
Elena N. Voropaeva, Tatyana I. Pospelova, Mikhail I. Voevoda, Vladimir N. Maksimov, Yuriy L. Orlov, Olga B. Seregina
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S2, Pp 35-44 (2019)
Abstract Background The knowledge about specific mechanisms generating TP53 dysfunction in diffuse large B-cell lymphoma is limited. The aim of the current study was to comprehensively explore TP53 gene variability resulting from somatic mutations, p
Externí odkaz:
https://doaj.org/article/ea42eca0394f4c969a991de02f32b02c
Autor:
Alla K. Ovsyannikova, Oksana D. Rymar, Elena V. Shakhtshneider, Vadim V. Klimontov, Elena A. Koroleva, Mikhail I. Voevoda
Publikováno v:
Сахарный диабет, Vol 22, Iss 1, Pp 88-94 (2019)
Maturity-Onset Diabetes of the Young (MODY) is a heterogeneous group of diseases associated with genes mutations leading to dysfunction of pancreatic β-cells. Among the 14 identified MODY variants, MODY 1–5 are the most studied. The article report
Externí odkaz:
https://doaj.org/article/948b836d2f294e77b3cc083993c40b71
Autor:
Elena N. Voropaeva, Yuriy L. Orlov, Tatiana I. Pospelova, Anna A. Gurageva, Mikhail I. Voevoda, Vladimir N. Maksimov, Olga B. Seregina, Maria I. Churkina
Publikováno v:
PeerJ, Vol 8, p e10335 (2020)
Background Rare single nucleotide polymorphisms (SNPs) are likely to be a crucial genetic factor for human diseases, including cancer. rs78378222 is rare SNP in 3′-untranslated region (UTR) of TP53 gene leading to disturbance of 3′-end mRNA proce
Externí odkaz:
https://doaj.org/article/c1a93b0d6aa0467ea22b4ae993435667
Autor:
Igor V. Maiborodin, Roman V. Maslov, Maxim E. Ryaguzov, Vitalina I. Maiborodina, Mikhail I. Voevoda
Publikováno v:
Annals of the Russian academy of medical sciences. 77:336-344
The therapeutic effect of multipotent stem cells (MSCs) is largely mediated by the secretion of exosomes/extracellular vesicles (EMSCs), which reflect the biophysical characteristics of MSC-producers and are considered more effective. The use of EMSC
Autor:
Tatiana V. Kirichenko, Yulia I. Ragino, Mikhail I. Voevoda, Saule J. Urazalina, Zukhra B. Khasanova, Varvara A. Orekhova, Vasily V. Sinyov, Margarita A. Sazonova, Alexander N. Orekhov, Igor A. Sobenin
Publikováno v:
Data in Brief, Vol 29, Iss , Pp - (2020)
The search for variants of mitochondrial genome associated with atherosclerosis, in particular, with carotid intima-media thickness (cIMT), is necessary to understand the role of the damage of mitochondrial genome in the development of atherosclerosi
Externí odkaz:
https://doaj.org/article/8a793a461870495f8c83bdc2f2ce0abe
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Dispersal of Homo sapiens across the globe during the last 200,000 years was accompanied by adaptation to local climatic conditions, with severe winter temperatures being probably one of the most significant selective forces. The TRPM8 gene codes for
Externí odkaz:
https://doaj.org/article/9c9b2b0c022941759eab56e333d63246
Autor:
Lyubomir I. Aftanas, Maksim S. Anisimenko, Darya A. Berdyugina, Aleksandr Yu. Garanin, Vladimir N. Maximov, Mikhail I. Voevoda, Natalya M. Vyalova, Nikolay A. Bokhan, Svetlana A. Ivanova, Konstantin V. Danilenko, Sergei P. Kovalenko
Publikováno v:
Frontiers in Genetics, Vol 9 (2019)
Depressive disorder (DD) is a widespread mental disorder. Although DD is to some extent inherited, the genes contributing to the risk of this disorder and its genetic mechanisms remain poorly understood. A recent large-scale genome-wide association C
Externí odkaz:
https://doaj.org/article/79bb92b97a8449f8abc3e13a09d5a214