Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mikhail Geyfman"'
Autor:
Hong Wang, Elyse van Spyk, Qiang Liu, Mikhail Geyfman, Michael L. Salmans, Vivek Kumar, Alexander Ihler, Ning Li, Joseph S. Takahashi, Bogi Andersen
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1061-1072 (2017)
Summary: The epidermis is a highly regenerative barrier protecting organisms from environmental insults, including UV radiation, the main cause of skin cancer and skin aging. Here, we show that time-restricted feeding (RF) shifts the phase and alters
Externí odkaz:
https://doaj.org/article/b77f90aebad144f7ba70d499a582855c
Autor:
Chiara Stringari, Hong Wang, Mikhail Geyfman, Viera Crosignani, Vivek Kumar, Joseph S. Takahashi, Bogi Andersen, Enrico Gratton
Publikováno v:
Cell Reports, Vol 10, Iss 1, Pp 1-7 (2015)
Through the use of bulk measurements in metabolic organs, the circadian clock was shown to play roles in organismal energy homeostasis. However, the relationship between metabolic and circadian oscillations has not been studied in vivo at a single-ce
Externí odkaz:
https://doaj.org/article/1f937f2e0e48456a99eef01250d5e891
Autor:
Kevin K Lin, Vivek Kumar, Mikhail Geyfman, Darya Chudova, Alexander T Ihler, Padhraic Smyth, Ralf Paus, Joseph S Takahashi, Bogi Andersen
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000573 (2009)
Hair follicles undergo recurrent cycling of controlled growth (anagen), regression (catagen), and relative quiescence (telogen) with a defined periodicity. Taking a genomics approach to study gene expression during synchronized mouse hair follicle cy
Externí odkaz:
https://doaj.org/article/a406f16a95c24a51a2b4ae7054ea2f88
Publikováno v:
Expert Opinion on Therapeutic Targets. 23:755-771
Introduction: In the past 30 years, only two drugs have received FDA approval for the treatment of androgenetic alopecia reflecting a lack of success in unraveling novel targets for pharmacological intervention. However, as our knowledge of hair biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e95667cdaa89f6b4131df6209bce23
https://doi.org/10.1080/14728222.2019.1659779
https://doi.org/10.1080/14728222.2019.1659779
Publikováno v:
Experimental Dermatology. 28:190-197
Acne remains as the most common skin disease in the United States even despite multiple approved topical and systemic medications available. These treatments available over the counter and by prescription can be classified based on comedolytic, antib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e50f2066dfadd1cbde6923557d53af
https://doi.org/10.1111/exd.13869
https://doi.org/10.1111/exd.13869
Autor:
Elyse N. Van Spyk, Kim Pham, Maksim V. Plikus, Mikhail Geyfman, Joseph S. Takahashi, Vivek Kumar, Bogi Andersen
Publikováno v:
Journal of Biological Rhythms. 30:163-182
Historically, work on peripheral circadian clocks has been focused on organs and tissues that have prominent metabolic functions, such as the liver, fat, and muscle. In recent years, skin has emerged as a model for studying circadian clock regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e0dd4fd652a9c0aa642c1bbb8b6547
https://doi.org/10.1177/0748730414563537
https://doi.org/10.1177/0748730414563537
Autor:
Mikhail Geyfman, Elyse N. Van Spyk, Bogi Andersen, Michael L. Salmans, Joseph S. Takahashi, Vivek Kumar, Ning Li, Alexander T. Ihler, Qiang Liu, Hong Wang
Publikováno v:
Wang, Hong; van Spyk, Elyse; Liu, Qiang; Geyfman, Mikhail; Salmans, Michael L; Kumar, Vivek; et al.(2017). Time-Restricted Feeding Shifts the Skin Circadian Clock and Alters UVB-Induced DNA Damage.. Cell reports, 20(5), 1061-1072. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/9183g35f
Cell Reports, Vol 20, Iss 5, Pp 1061-1072 (2017)
Cell Reports, Vol 20, Iss 5, Pp 1061-1072 (2017)
Summary: The epidermis is a highly regenerative barrier protecting organisms from environmental insults, including UV radiation, the main cause of skin cancer and skin aging. Here, we show that time-restricted feeding (RF) shifts the phase and alters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43872c924deca7cae715e279493eee4
http://www.escholarship.org/uc/item/9183g35f
http://www.escholarship.org/uc/item/9183g35f
Publikováno v:
Biological Reviews. 90:1179-1196
The hair follicle (HF) represents a prototypic ectodermal–mesodermal interaction system in which central questions of modern biology can be studied. A unique feature of these stem-cell-rich mini-organs is that they undergo life-long, cyclic transfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448305b38f47e4bea728facabcda4653
https://doi.org/10.1111/brv.12151
https://doi.org/10.1111/brv.12151