Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Mikhail Gavrilin"'
1
HIV infection associated oxidation of innate immune proteins in the human lung mucosa alters the host response to Mycobacterium tuberculosis infection
Autor: Anwari Akhter, Angélica Olmo-Fontánez, Juan Moliva, Abul Azad, Holden Kelley, Julia Scordo, Mikhail Gavrilin, Mark Wewers, Jordi Torrelles
Publikováno v: The Journal of Immunology. 202:62.20-62.20
Tuberculosis (TB) is the leading killer of people with HIV infection. Limited studies have considered HIV infection associated changes to the soluble components of the innate immune system in the alveolar lining fluid (ALF) as a contributing factor t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a60546da97bd3b2d095774f36863ec79
https://doi.org/10.4049/jimmunol.202.supp.62.20
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3
Differential caspase regulation of actin dynamics during Legionella pneumophila infection (INC4P.324)
Autor: Kyle Caution, Anwari Akhter, Hoda Hassan, Mia Tazi, Amro Ahmed, Sheshadri Hoque, Mohammed Ghonime, Mikhail Gavrilin, Amal Amer
Publikováno v: The Journal of Immunology. 194:125.3-125.3
Legionella pneumophila (Legionella) is the causative agent of Legionnaires’ disease. Clearance of Legionella requires efficient phagolysosomal fusion. Regulation of the host actin cytoskeleton is crucial for proper vesicle trafficking. It has been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28bfd520bf24fa8b8143e3a792f172fc
https://doi.org/10.4049/jimmunol.194.supp.125.3
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4
Receptor interacting protein-2 plays a critical role in human lung epithelial cells survival in response to Fas-induced cell-death (IRM9P.731)
Autor: Mohd. Rahman, Kruthika Sundaram, Das Srabani, Mikhail Gavrilin, Mark Wewers
Publikováno v: The Journal of Immunology. 192:128.14-128.14
Lung epithelial cell death is critical to acute lung injury. It is known that FasL plays a prominent role in lung cell death and may work in part through activation of the receptor interacting protein-2 (RIP2). RIP2 is serine/threonine kinase with a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3bbed55eeeb6c0b0e857c602c49f514
https://doi.org/10.4049/jimmunol.192.supp.128.14
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5
Inflammatory protease, caspase-1, is secreted from monocytes in a stably active form in response to inflammasome activation (INM3P.441)
Autor: Obada Shamaa, Mohammed Ghonime, Das Srabani, Mikhail Gavrilin, Mark Wewers
Publikováno v: The Journal of Immunology. 192:57.4-57.4
Caspase-1 is an inflammatory protease which is required for activation of the pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18, in addition to a role in a form of cell death termed pyroptosis. Caspase-1 is synthesized as a zymogen which
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e72f6970ce8e3a3734779ac83fa434c
https://doi.org/10.4049/jimmunol.192.supp.57.4
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6
Critical role for extracellular-regulated kinase signaling in endotoxin priming of human monocyte NLRP3 inflammasome (IRM5P.705)
Autor: Mohammed Ghonime, Obada Shamaa, Ramadan Eldomany, Das Srabani, Mikhail Gavrilin, Mark Wewers
Publikováno v: The Journal of Immunology. 192:62.6-62.6
Inflammasomes play key roles in the innate immune response to pathogens and tissue injury. Inflammasome assembly involves two distinct steps; priming and activation, which together trigger caspase-1 to process and release IL-1β, IL-18 and in some se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::626b8e60c622a0269cc7cb2465770f51
https://doi.org/10.4049/jimmunol.192.supp.62.6
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7
Pro-inflammatory response of human bronchial epithelial cells following Burkholderia cenocepacia infection: focus on IL-1β. (P1265)
Autor: Devyn Gillette, Prexy Shah, Thomas Cremer, Mikhail Gavrilin, Beth Besecker, Anasuya Sarkar, Daren Knoell, Estelle Cormet-Boyaka, Mark Wewers, Jonathan Butchar, Susheela Tridandapani
Publikováno v: The Journal of Immunology. 190:56.15-56.15
Burkholderia cenocepacia is the causative agent of the fatal lung disease, Cepacia syndrome. Epithelial cells are the first cells challenged in airway infections, yet, their pro-inflammatory response to B. cenocepacia remains under investigated. Here
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6ad3e61616ee79abf7248ae84390980
https://doi.org/10.4049/jimmunol.190.supp.56.15
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