Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Mikhail Drobizhev"'
Autor:
Saaya Hario, Giang N. T. Le, Hikaru Sugimoto, Kei Takahashi-Yamashiro, Suguru Nishinami, Hirofumi Toda, Selene Li, Jonathan S. Marvin, Shinya Kuroda, Mikhail Drobizhev, Takuya Terai, Yusuke Nasu, Robert E. Campbell
Publikováno v:
ACS Central Science, Vol 10, Iss 2, Pp 402-416 (2024)
Externí odkaz:
https://doaj.org/article/ff3be682f210460cb3864cd6aa0e4fe9
Autor:
Yusuke Nasu, Abhi Aggarwal, Giang N. T. Le, Camilla Trang Vo, Yuki Kambe, Xinxing Wang, Felix R. M. Beinlich, Ashley Bomin Lee, Tina R. Ram, Fangying Wang, Kelsea A. Gorzo, Yuki Kamijo, Marc Boisvert, Suguru Nishinami, Genki Kawamura, Takeaki Ozawa, Hirofumi Toda, Grant R. Gordon, Shaoyu Ge, Hajime Hirase, Maiken Nedergaard, Marie-Eve Paquet, Mikhail Drobizhev, Kaspar Podgorski, Robert E. Campbell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract l-Lactate is increasingly appreciated as a key metabolite and signaling molecule in mammals. However, investigations of the inter- and intra-cellular dynamics of l-lactate are currently hampered by the limited selection and performance of l-
Externí odkaz:
https://doaj.org/article/92c1078698bf4a70b5ef20a844149591
Autor:
Atanu Maiti, Cosmo Z. Buffalo, Saumya Saurabh, Felipe Montecinos-Franjola, Justin S. Hachey, William J. Conlon, Geraldine N. Tran, Bakar Hassan, Kylie J. Walters, Mikhail Drobizhev, W. E. Moerner, Partho Ghosh, Hiroshi Matsuo, Roger Y. Tsien, John Y. Lin, Erik A. Rodriguez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The small Ultra-Red Fluorescent Protein (smURFP) represents a new class of fluorescent protein with exceptional photostability and brightness derived from allophycocyanin in a previous directed evolution. Here, we report the smURFP crystal s
Externí odkaz:
https://doaj.org/article/c7b97c5ea32a4f34823ce6ae4a9c9f7e
Autor:
Yusuke Nasu, Ciaran Murphy-Royal, Yurong Wen, Jordan N. Haidey, Rosana S. Molina, Abhi Aggarwal, Shuce Zhang, Yuki Kamijo, Marie-Eve Paquet, Kaspar Podgorski, Mikhail Drobizhev, Jaideep S. Bains, M. Joanne Lemieux, Grant R. Gordon, Robert E. Campbell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
l-lactate is an important intercellular energy currency. Here the authors report a genetically encoded biosensor eLACCO1.1 to monitor extracellular l-lactate; they use eLACCO1.1 to image extracellular l-lactate in cultured mammalian cells and brain t
Externí odkaz:
https://doaj.org/article/56b5eb5b8e5543099fe7a7880622d7ac
Autor:
Sheng-Yi Wu, Yurong Wen, Nelson B C Serre, Cathrine Charlotte Heiede Laursen, Andrea Grostøl Dietz, Brian R Taylor, Mikhail Drobizhev, Rosana S Molina, Abhi Aggarwal, Vladimir Rancic, Michael Becker, Klaus Ballanyi, Kaspar Podgorski, Hajime Hirase, Maiken Nedergaard, Matyáš Fendrych, M Joanne Lemieux, Daniel F Eberl, Alan R Kay, Robert E Campbell, Yi Shen
Publikováno v:
PLoS Biology, Vol 20, Iss 9, p e3001772 (2022)
Potassium ion (K+) plays a critical role as an essential electrolyte in all biological systems. Genetically-encoded fluorescent K+ biosensors are promising tools to further improve our understanding of K+-dependent processes under normal and patholog
Externí odkaz:
https://doaj.org/article/3acdec6eadb747dba6da2bd4ef33714b
Autor:
Molly J. Kirk, Brittany R. Benlian, Yifu Han, Arya Gold, Ashvin Ravi, Parker E. Deal, Rosana S. Molina, Mikhail Drobizhev, Dion Dickman, Kristin Scott, Evan W. Miller
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
We combine a chemically-synthesized, voltage-sensitive fluorophore with a genetically encoded, self-labeling enzyme to enable voltage imaging in Drosophila melanogaster. Previously, we showed that a rhodamine voltage reporter (RhoVR) combined with th
Externí odkaz:
https://doaj.org/article/8bb0c427fcf548cfaf73e51d8ca6a5f4
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/757d277d910743bda4fb2386517a5000
Autor:
Mikhail Drobizhev, Rosana S. Molina, Patrik R. Callis, J. Nathan Scott, Gerard G. Lambert, Anya Salih, Nathan C. Shaner, Thomas E. Hughes
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Genetically encoded probes with red-shifted absorption and fluorescence are highly desirable for imaging applications because they can report from deeper tissue layers with lower background and because they provide additional colors for multicolor im
Externí odkaz:
https://doaj.org/article/47722abd44bb40a78f03b99908ce6b32
Publikováno v:
Bio-Protocol, Vol 10, Iss 2 (2020)
Two-photon laser scanning microscopy (2PLSM) is a state-of-the-art technique used for non-invasive imaging deep inside the tissue, with high 3D resolution, minimal out-of-focus photodamage, and minimal autofluorescence background. For optimal applica
Externí odkaz:
https://doaj.org/article/7d88705119334194ac8a2f06f72504ab
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 770 (2022)
Red fluorescent proteins and biosensors built upon them are potentially beneficial for two-photon laser microscopy (TPLM) because they can image deeper layers of tissue, compared to green fluorescent proteins. However, some publications report on the
Externí odkaz:
https://doaj.org/article/6c75c94e67194e42b557b50650f2377a