Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mikhail Chtcherbinine"'
Autor:
Ilana Chefetz, Edward Grimley, Kun Yang, Linda Hong, Ekaterina V. Vinogradova, Radu Suciu, Ilya Kovalenko, David Karnak, Cynthia A. Morgan, Mikhail Chtcherbinine, Cameron Buchman, Brandt Huddle, Scott Barraza, Meredith Morgan, Kara A. Bernstein, Euisik Yoon, David B. Lombard, Andrea Bild, Geeta Mehta, Iris Romero, Chun-Yi Chiang, Charles Landen, Benjamin Cravatt, Thomas D. Hurley, Scott D. Larsen, Ronald J. Buckanovich
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3061-3075.e6 (2019)
Summary: Ovarian cancer is typified by the development of chemotherapy resistance. Chemotherapy resistance is associated with high aldehyde dehydrogenase (ALDH) enzymatic activity, increased cancer “stemness,” and expression of the stem cell mark
Externí odkaz:
https://doaj.org/article/21d10f5934934f7c8c9e8ddf07b5d168
Autor:
Vaishnavi Muralikrishnan, Fang Fang, Tyler C. Given, Ram Podicheti, Mikhail Chtcherbinine, Tara X. Metcalfe, Shruthi Sriramkumar, Heather M. O’Hagan, Thomas D. Hurley, Kenneth P. Nephew
Publikováno v:
Cancers; Volume 14; Issue 14; Pages: 3437
Ovarian cancer is a deadly disease attributed to late-stage detection as well as recurrence and the development of chemoresistance. Ovarian cancer stem cells (OCSCs) are hypothesized to be largely responsible for the emergence of chemoresistant tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4447dea889eb3723012c0b5f9cfa5df7
Autor:
Scott J. Barraza, Radu M. Suciu, Thomas D. Hurley, Mikhail Chtcherbinine, David Karnak, Euisik Yoon, Kara A. Bernstein, Ilya Kovalenko, Chun-Yi Chiang, Geeta Mehta, Ekaterina V. Vinogradova, Benjamin F. Cravatt, Brandt C. Huddle, Andrea H. Bild, Ronald J. Buckanovich, Iris L. Romero, Ilana Chefetz, Cynthia A. Morgan, Linda Hong, David B. Lombard, Edward Grimley, Scott D. Larsen, Charles N. Landen, Cameron D. Buchman, Meredith A. Morgan, Kun Yang
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3061-3075.e6 (2019)
Summary: Ovarian cancer is typified by the development of chemotherapy resistance. Chemotherapy resistance is associated with high aldehyde dehydrogenase (ALDH) enzymatic activity, increased cancer “stemness,” and expression of the stem cell mark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2cac15fa345ecc463e87abb08cc8ba
http://www.sciencedirect.com/science/article/pii/S2211124719302037
http://www.sciencedirect.com/science/article/pii/S2211124719302037
Autor:
Brandt C. Huddle, Bo Wen, Cameron D. Buchman, Bikash Debnath, Mikhail Chtcherbinine, Jeremy Felton, Cyrus Takahashi, Edward Grimley, Ronald J. Buckanovich, Scott D. Larsen, Stacy McGonigal, Nouri Neamati, Duxin Sun, Thomas D. Hurley, Shu Pan, Siwei Li, Shuai Mao
Publikováno v:
Eur J Med Chem
There is strong evidence that inhibition of one or more Aldehyde Dehydrogenase 1A (ALDH1A) isoforms may be beneficial in chemotherapy-resistant ovarian cancer and other tumor types. While many previous efforts have focused on development of ALDH1A1 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547d607c7e64542a6c0f897fe2c17150
https://pubmed.ncbi.nlm.nih.gov/33341649
https://pubmed.ncbi.nlm.nih.gov/33341649
Autor:
Cameron D. Buchman, Siwei Li, Jeremy Felton, Geeta Mehta, Bikash Debnath, Edward Grimley, Scott D. Larsen, Brandt C. Huddle, Ronald J. Buckanovich, Duxin Sun, Pooja Mehta, Mikhail Chtcherbinine, Thomas D. Hurley, Kun Yang, Cynthia A. Morgan, Nouri Neamati
Publikováno v:
Journal of medicinal chemistry. 61(19)
Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer stem-like cells and in chemoresistance; however, which isoform is prefer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035234b9aea738665d2f4f1229c340fd
https://pubmed.ncbi.nlm.nih.gov/30221940
https://pubmed.ncbi.nlm.nih.gov/30221940
Publikováno v:
Cancer Research. 77:2552-2552
Cell fusion is a physiological process utilized by a variety of biological systems during fertilization, embryogenesis, and cellular differentiation and morphogenesis. During the malignant transformation of breast and bone tissues, normal and maligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a15542ac47ccd9cd9f2d27b2a98d3846
https://doi.org/10.1158/1538-7445.am2017-2552
https://doi.org/10.1158/1538-7445.am2017-2552